Building Blocks

D-Leucine-d10-N-Fmoc is a cox-2 inhibitor that inhibits the activity of cyclooxygenase enzymes, which are involved in the formation of prostaglandins from arachidonic acid. It has been shown to have an anticancer effect against cells in culture and also inhibits the growth of tumors in mice. D-Leucine-d10-N-Fmoc is a molecule with a structure similar to celecoxib, a selective COX 2 inhibitor that is currently used for treatment of arthritis. However, unlike celecoxib, D-Leucine-d10-N-Fmoc does not inhibit any other isoforms of cyclooxygenase.END>>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,3-dihydro-1H-indene-4-carbaldehyde is an antibacterial agent that has been shown to be active against bacteria and yeast. It is used in the preparation of samples for analysis using solid phase microextraction (SPME). The extraction procedure involves the use of a non-polar solvent to extract analytes from a solid matrix. The sample preparation technique can be used when the analytes are not soluble in water. 2,3-Dihydro-1H-indene-4-carbaldehyde inhibits β-glucosidase activity and fatty acid synthesis. This compound also has antiinflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis by inhibiting β-glucosidase activity.
2,3-Dihydro-1H-indene 4 carbaldehyde is an isomer of dimethyl fumarate and can be converted into this form by hydrogenation

Versatile small molecule scaffold

2-(Furan-2-yl)-1,3-thiazolidine is a chemical compound that is used as a reagent in organic synthesis. It has been shown to be an efficient sulfur-promoted atom transfer agent for the aerobic oxidation of thiols, such as cysteine. 2-(Furan-2-yl)-1,3-thiazolidine has also been studied as a catalyst in the formation of microemulsions. The catalytic activity of this molecule may be enhanced by its ability to form structured intermediates at the interface between water and oil phases. This reaction product is stable enough to withstand repeated phase changes and can be used for the production of glycols from diols.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Amphetamine is a psychostimulant and sympathomimetic that is used to treat attention-deficit hyperactivity disorder, narcolepsy, and obesity. Amphetamine is structurally similar to phenylethylamine, a naturally occurring trace amine found in humans. Amphetamine has been shown to bind with high affinity to tissues in the heart, lungs, stomach, and intestines. It also binds with moderate affinity to the liver. Amphetamine can be detected by analyses of chemical structures using diode-array detection or mass spectrometry. In addition, amphetamine can be detected in urine using liquid chromatography or gas chromatography/mass spectrometry. Amphetamines are addictive and have been shown to cause long-term damage in animal models of addiction. Cathinones are related compounds that have been found in human urine samples and have been shown to be toxicologically similar to amphetamines.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold