Building Blocks

<p>Applications Cyclopentyl chloride (cas# 930-28-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Hydroxymandelic Acid (cas# 17119-15-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-hydroxy-5-iodobenzoic Acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labelled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.<br>References Tu, Z. et al.: J. Med. Chem., 50, 3194 (2007); Sellarajah, S. et al.: J. Med. Chem., 47, 5515 (2004);<br></p>

<p>Stability Volatile<br>Applications N-Isopropyl-N-methylamine (cas# 4747-21-1) is a compound useful in organic synthesis.<br> E0<br></p>

<p>Applications 4-Hexen-1-ol, (4E)- (cas# 928-92-7) is a useful research chemical.<br></p>

<p>Applications β-Hydroxyisovaleric Acid is a metabolite of the essential amino acid Leucine and is synthesized in the human body. Studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nissen, S. et al.: J. Appl. Physiol., 81, 2095 (1996); Wilson, G.J. et al.: Nutrit. Metab., 5, 1 (2008); Mock, D.M. et al.: Am. J. Clin. Nutrit., 76, 1061 (2002);<br></p>

<p>Applications 5-Chloro-2-methylphenol can be used in the preparation of dichlorotoluqinones.<br>References James, C., et al.: J. Org. Chem., 16, 328 (1951)<br></p>

<p>Applications Monobenzyl Malonate is a useful synthetic intermediate. It was used to synthesize constrained cyclic agonists of the cholecystokinin CCK-B receptor. It was also used to prepare aspartate transcarbamoylase inhibitors.<br>References Blommaert, A., et al.: J. Med. Chem., 40, 647 (1997); Coudray, L., et al.: Bioorg. Med. Chem., 17, 7680 (2009)<br></p>

<p>Applications 1-(4-Hydroxyisoxazole)-carboxylic Acid (cas# 178316-77-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Dowex® 1X4 Chloride Form is an adsorbent material, strongly basic (type I) anion exchange resin used in pharmaceuticals.<br></p>

<p>Applications 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.<br>References Yamazaki, Y. et al.: Zeitsch. Naturforsch. C: J. Biosci., 65, 49 (2010); Kay, W.W. et al.: Gen. Pharmacol., 8, 201 (1977); Ghebregzabher, M. et al.: J. Chrom. Biomed. Appl., 222, 191 (1981);<br></p>

<p>Applications 1-(Bromoacetyl)pyrene is a novel photoinitiator.<br></p>

<p>Stability Moisture Sensitive<br>Applications 5-Bromoacetyl-2-hydroxybenzamide is a reagent used in the synthesis of bisthiazole derivatives and novel 7-methylguanine derivatives targeting influenza polymerase binding domains.<br>References Pautus, S. et al.: J. Med. Chem., 56, 8915 (2013); Araniciu, C. et al.: Revista. Chim., 64, 1067 (2013);<br></p>

<p>Applications bis(2,2,2-trifluoroethyl) carbonate (cas# 1513-87-7) is a useful research chemical.<br></p>

<p>Applications 2,4,5-trichlorobenzoic acid (cas# 50-82-8) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>