Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Methanesulfinyl-3-methylbenzene is a white crystalline solid that belongs to the class of aromatic compounds. It has a melting point of 134° C and a boiling point of 350° C. 1-Methanesulfinyl-3-methylbenzene has been shown to have an x-ray crystal structure with four asymmetric units. This compound has also been analyzed by elemental analyses, which showed it contains hydrogen (H), carbon (C), sulfur (S), and oxygen (O) elements. 1-Methanesulfinyl-3-methylbenzene is soluble in organic solvents such as ethyl acetate, but insoluble in water or alcohols. It can be recrystallized from solvents such as ethyl acetate or diethyl ether. 1-Methanesulfinyl-3-methylbenzene is used for the synthesis of other organic compounds and for research purposes.

Versatile small molecule scaffold

Versatile small molecule scaffold

4,4,4-Trichloro-3-hydroxybutanoic acid is a benzyl ester of the fatty acid 4,4,4-trichloro-3-hydroxybutanoic acid. The molecule has an optical isomer that can be synthesized from the corresponding symmetrical compound. The synthesis of 4,4,4-trichloro-3-hydroxybutanoic acid involves the reaction of benzyl alcohol with trichloromethyl chloride in the presence of an acid catalyst. This reaction yields two isomers: one of which has the same configuration as the starting material and one that is an optical isomer. The latter can be converted to its antipode by hydrogenation or by heating with sodium methoxide in methanol.

Versatile small molecule scaffold

2-Bromohexanamide is a receptor binding molecule that binds to the 5-HT2A receptor. 2-Bromohexanamide has been shown to be effective in treating autoimmune diseases, including psoriasis and rheumatoid arthritis. It is also used for the treatment of cancer, specifically for the prevention of chemotherapy-induced nausea and vomiting. 2-Bromohexanamide has been shown to bind to the 5-HT7 receptor, which is involved in regulating mood and appetite. The drug has a hydroxyl group that reacts with nucleophilic attack at the amide bond to form an acid complex. This reaction mechanism results in a molecule that can bind to receptors and cause receptor activity.

Versatile small molecule scaffold

The chemical name for 1,2,3,4,5-Pentamethyl-6-nitrobenzene is 6-Nitroso-1,1′-(3,3′-dimethylpropyl)-1,2,3,-4,5-pentamethylbenzene. It is a colorless liquid that has a boiling point of 190 °C and density of 1.0 g/mL. 6NMN is soluble in acetone and ethanol but insoluble in water. This compound has been shown to be an effective antihypertensive agent with reversible vasodilator properties. Clinical development of 6NMN has been hindered by the lack of a suitable animal model for congestive heart failure (CHF). There are no known functional groups on this molecule; however it does have a phenolic group at the para position and hydroxyl group at the meta position on the benzene ring. The compound also has two nitro groups that

Versatile small molecule scaffold

Tetrafluoropyrazine is a fluorinated electrophilic compound that serves as an oxygen nucleophile. It reacts with hydrochloric acid and chlorine to form hydrogen chloride and tetrafluoropyrazine hydrochloride, respectively. Tetrafluoropyrazine has been shown to bind to the 5-HT7 receptor in rat brains, which may be due to its chemical similarity to serotonin. Magnetic resonance spectroscopy revealed that tetrafluoropyrazine contains nitrogen atoms in its structure. The polymer film structure of this molecule was determined by X-ray crystallography. Tetrafluoropyrazine also has the ability to oxidize polyethylene glycols and polypropylene glycols, which may be due to its ability to act as an electron acceptor.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold