Building Blocks

Versatile small molecule scaffold

7-Methoxy-1,2-dihydronaphthalene is a cyclic compound that has been synthesized from 7-methoxy-1,2,3,4-tetrahydronaphthalene. It is a crystalline form that is soluble in organic solvents. The chemical structure of the compound is similar to the naphthalenes and it has been used as an intermediate for the synthesis of ferulic acid and other compounds. 7-Methoxy-1,2-dihydronaphthalene has also been used in treatments for organisms such as fungi and bacteria. This compound has been investigated for its chiral properties and radical coupling with biphenyl.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Amino-2-methoxyphenol is a phenolic compound that is found in the human body. It has been shown to have significant anti-inflammatory activity and can be used as an analgesic. The mechanism of action of 4-Amino-2-methoxyphenol is not fully understood, but it may inhibit the production of reactive oxygen species and promote the synthesis of prostaglandins. The drug also inhibits lipoprotein lipase and increases serum cholesterol levels in rats.

Versatile small molecule scaffold

4-Propylcyclohexan-1-ol is a liquid crystal that has been shown to be an activator of eugenol. It is a reactive intermediate in the reaction with bond cleavage. It has been shown to have a kinetic rate that is dependent on the number of carbon walls and metal ions. 4-Propylcyclohexan-1-ol can cause dehydration (loss of water) and detergent compositions can be made using it as a functional group. The hydroxyl group present in this molecule, combined with its functional groups, makes this liquid crystal useful for the production of polymers and plastics. This monomer can also polymerize into polyesters, polyamides, or polyurethanes.

2,3-Dihydro-1H-indole-5-sulfonic acid amide (DAS) is a receptor agonist. It has been shown to be selective for the alpha adrenergic receptor and has agonist activity in human tissue. DAS has n-substituted phenyl groups that are important for binding to the alpha adrenergic receptor, which are substituted at positions adjacent to the sulfonamide group. The pharmacophore of this compound is an aromatic ring with a sulphonamide group on one side and two n-substituted phenyl groups on the other side.

1-Pyridin-4-yl-imidazolidin-2-one is a potent inhibitor of the growth hormone receptor, which in turn prevents the activation of the insulin receptor and glycogenolysis. It has been shown to attenuate cachexia in mice by reducing their weight loss. 1Pyridin-4-yl-imidazolidin-2-one also exerts an antihypertensive effect on congestive heart failure by inhibiting alpha 2 adrenergic receptors. This drug has been shown to have a stimulatory effect on premarin production and to be an effective insecticide against aphids, mites, and caterpillars.

Versatile small molecule scaffold

2,6-Dimethyl-3-pyridinecarboxylic acid methyl ester is a ketone with the chemical formula C5H8O2. It is a polysubstituted vinyl compound that contains two methyl groups. This chemical can be synthesized by the dehydrogenation of 2,6-dimethyl-3-pyridinecarboxylic acid with diels-alder and tetrahydropyridine catalysts. The synthesis of this compound was first reported in 1887 by Diels and Alder. 2,6-Dimethyl-3-pyridinecarboxylic acid methyl ester is an important intermediate in the preparation of pyridines, as well as cycloaddition reactions that form vinyl ketones or dienes from ethylenic compounds.

Versatile small molecule scaffold

Sodium 2-fluorobenzene-1-sulfinate is an arylation agent that can be used to synthesize substituted phenols. It is a regioselective reagent, which means it only reacts at the para position of the aromatic ring. The carbonate group can be removed by treatment with tripotassium phosphate in acidic solution, yielding the corresponding n-oxide. Sodium 2-fluorobenzene-1-sulfinate can also be used for palladium-catalyzed arylating reactions. This reaction requires a stoichiometric amount of triphenylphosphine and yields excellent yields. It reacts with diphenylphosphine to form the corresponding oxide in high yield. Sodium 2-fluorobenzene-1-sulfinate is commercially available and synlett has been reported.

5-Chloroisoindoline is a compound that can be synthesized from amines. It is a cyclic compound with a high yield. 5-Chloroisoindoline can be used to synthesize other compounds, including pharmaceuticals and dyestuffs.

4-Bromoisoindoline is an industrial chemical that belongs to the group of medicines. It is synthesized by a reaction of 2,4-dichlorobenzoyl chloride with 4-aminoindoline. The synthesis process is not yet known.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold