Building Blocks

<p>Versatile small molecule scaffold</p>

<p>1-Allyl-2-bromobenzene is an organic solvent that is used in the synthesis of fatty acids and bromophenols. It is a gaseous liquid at room temperature and pressure, but it can be condensed to liquid form by cooling. 1-Allyl-2-bromobenzene reacts with polydimethylsiloxane to produce amides or chlorides. The reaction proceeds under conditions where there are no competing reactions such as alkylation or biomolecular oxidation. It has been used extensively in the synthesis of fatty acid esters, amides, and nitriles. This organic solvent is volatile at room temperature and pressure and its boiling point is below 100 degrees Celsius. 1-Allyl-2-bromobenzene has a low viscosity and high surface tension which make it useful for certain types of chemical reactions on surfaces such as in the production of reaction products from naphthalene.br&gt;br&gt;</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Ethyl 2-methoxyethanecarboximidate hydrochloride is an amido amide with antibacterial activity. It is a carboxylic acid compound and an isomer of ethyl 2-methylpropanoate. This active form has been shown to inhibit bacterial growth by binding to the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. The antimicrobial activity of this agent has been demonstrated in vitro against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, Streptococcus pyogenes, and Enterobacter cloacae. Ethyl 2-methoxyethanecarboximidate hydrochloride also inhibits the production of bacterial endotoxin and has shown antibiotic activity against Gram-positive organisms.

<p>9-Oxo-9,10-dihydroacridine-2-carboxylic acid is a fatty acid oxidation product that has been shown to induce apoptosis in the mitochondria of tumor cells. This process is mediated by the release of cytochrome c from the mitochondria into the cytosol. It also binds to antigens in the extracellular matrix and induces autoantibodies against these antigens. 9-Oxo-9,10-dihydroacridine-2-carboxylic acid has been found to bind to caspase family members and potentiate their activity. 9oxoacridine 2 carboxylic acid is also a potential antitumor agent that shows histological evidence of tumor regression in rats injected with sarcoma 180 cells.<br> 9oxoacridine 2 carboxylic acid also binds to DNA and inhibits protein synthesis by blocking transcriptional initiation at G</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-nitronicotinic acid is an inhibitor of HIV-1 reverse transcriptase. It binds reversibly to the active site of the enzyme and blocks its ability to synthesize DNA, thus inhibiting HIV replication. 2-Chloro-5-nitronicotinic acid also inhibits the activity of wild type and mutant forms of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with high potency. This drug has been shown to be effective against nevirapine resistant HIV strains. The molecular modeling studies suggest that 2-chloro-5 nitronicotinic acid binds to a hydrophobic pocket in the active site of HIV reverse transcriptase, which is different from other inhibitors such as AZT, ddI, and ddC.</p>

<p>2-Chloro-5-hydroxynicotinic acid is a chemical compound that has been isolated from the bark of the plant Cinchona officinalis. It is an intermediate in the biosynthesis of quinine and other cinchona alkaloids. 2-Chloro-5-hydroxynicotinic acid is also used as an intermediate in the synthesis of other compounds, including herbicides and pesticides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzofuran-2-carbohydrazide (1BFC) is an antibacterial agent that belongs to the class of nitrogenous compounds. It is a member of the benzofuran derivatives and has been shown to have significant antifungal activity against flavus, cleavage activity against s. aureus and staphylococcus, and hypoglycemic activity in mice. 1BFC has been found to be more active than fluconazole against Candida albicans, but less active than fluconazole against Saccharomyces cerevisiae.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>