Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,6-Naphthyridine-2,4-diol is a trifluoromethyl carboxylic acid that is used in the synthesis of pharmaceuticals. The compound is a carboxylic acid type cation with an integer number of 2 and 4 carbon atoms. 1,6-Naphthyridine-2,4-diol is also known to produce symptoms such as sensitivity and prophylactically for allergy.
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Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Chloro-5-phenylpyrimidine is a copper(I) complex with the chemical formula [CuCl(PY)]. It is synthesized by reacting an equimolar mixture of 4-chloro-5-phenylpyrimidine and CuCl. The thermodynamic, kinetic, and stereochemical properties of this compound have been extensively studied. This compound belongs to the class of amidines and has been shown to interact with transition metals, such as copper. 4-Chloro-5-phenylpyrimidine can be used in organic synthesis reactions because it readily undergoes nucleophilic substitution reactions. The reaction between this compound and nucleophiles leads to the formation of stereoisomers that are chiral at the carbon atom in the pyrimidinone ring.

Versatile small molecule scaffold

N-Boc-3-methoxyaniline is a chemical compound that belongs to the class of nitroreductase inhibitors. It has been shown to inhibit tumour growth by targeting the tumor microenvironment and inhibiting the production of reactive oxygen species. N-Boc-3-methoxyaniline also has anti-angiogenic properties, which may be due to its ability to suppress the production of nitric oxide. This agent can be used for monitoring and controlling cancer stem cells in vitro and in vivo. The fluorescent probes are suitable for imaging, measuring, and quantifying this type of cell.

3-Cyclohexanecarbonylpyridine is a triazole with a nitrogen atom in the ring. It has a pyridine and two substituents, one of which is positioned on the 3-position and the other on the 6-position. This compound has strong antifungal activity, as demonstrated by screening in vitro studies. 3-Cyclohexanecarbonylpyridine also had high activity against phytopathogenic fungi such as Fusarium oxysporum, Rhizoctonia solani, Botrytis cinerea, and Alternaria brassicae. The fungicidal activity of this compound may be due to its inhibitory effect on protein synthesis.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Amino-3-methylhexanoic acid is a synthetic amino acid analog of the branched-chain amino acids leucine, isoleucine, and valine. It was originally developed as a treatment for thrombosis, but has been found to have antiviral properties. 2-Amino-3-methylhexanoic acid inhibits the action of enzymes that catalyze reactions in the synthesis of polypeptides, such as proteases (thrombin inhibitors) and peptidases. 2-Amino-3-methylhexanoic acid also inhibits viruses by preventing their replication. It does this by hydrogen bonding interactions with the viral capsid and preventing access to the RNA genome or protein coat. The chemical reaction between 2-amino hexanoic acid and an acid solution produces carbon dioxide gas.