Building Blocks

2-Hydroxy-2-phenylbutanoic acid is a ligand that can bind to metal ions. It has a molecular electrostatic potential of -0.07 and a low vibrational frequency of 0.01. It has been shown that this ligand can be immobilized on surfaces where it can be used for the determination of amino acids, expressed proteins, and chiral compounds. This ligand has been shown to have good binding affinity for metal ions which makes it a useful tool in immobilization studies. 2-Hydroxy-2-phenylbutanoic acid is an amide that contains two hydroxy groups, one phenyl group, and one carboxylic acid group. It is also chiral due to its asymmetric carbon atom which means that there are two different forms of the molecule, one being levorotary (R) and the other being dextrorotary (S). The functional theory shows that 2-hydroxy-2

Versatile small molecule scaffold

Versatile small molecule scaffold

Tris(hydroxymethyl)propane is a diphenyl ether that has been shown to have an electrochemical impedance spectroscopy (EIS) spectrum in the human serum that is similar to those of other known antioxidants. Tris(hydroxymethyl)propane has been shown to protect against light-induced damage in human skin cells, and it also has radiation protective effects. Tris(hydroxymethyl)propane has also been shown to interact with trimethylolpropane, which is another antioxidant, and this interaction may affect the effectiveness of each agent. Tris(hydroxymethyl)propane inhibits lipid peroxidation by inhibiting the oxidation of fatty acids and hydroxyl groups on proteins.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Chloro-4-(iodomethyl)benzene (1CI) is a chlorinating agent that is used to produce aliphatic chlorinated compounds. It can be used for the alkylation of alcohols, as well as the chlorination of halides. 1CI has been shown to react with benzene in a synergistic manner when irradiated. In addition, it can be used for the preparation of iodides by reacting with sodium or potassium iodide in the presence of an alcohol and a catalyst. 1CI reacts with chloride ions to produce cyclic compounds in the microwave region. The reaction requires an electron transfer agent, such as copper chloride or silver nitrate, and yields are dependent on the type of alcohol used, which can be either aliphatic or cyclic.

Versatile small molecule scaffold

Versatile small molecule scaffold

2,4-Dibromo-1,3-oxazole is a nitro compound and an important intermediate in the synthesis of herbicides. It is also used to produce coatings and as a reagent for organic synthesis. The compound can be synthesized by the palladium-catalyzed coupling of phenyl bromides with 2,4-dichloro-1,3-oxazole. 2,4-Dibromo-1,3-oxazole has been shown to have potent horticultural activity against plant diseases caused by anions such as fusarium oxysporum. This compound has a pharmacokinetic profile that is favourable for oral administration in humans. The lysine analogues are converted into picolinic acid and then to 2,4-dibromo-1,3-oxazole in the body. The dialkylamino substituents on the molecule are believed to be responsible

3-Hydroxy-4-nitrobenzaldehyde is a ternary complex, which consists of three molecules that are bound to each other in a specific way. It has been observed in the nmr spectra and it has been proposed as a fluorescence probe for the detection of hydrogen bonds. 3-Hydroxy-4-nitrobenzaldehyde catalyzes the reaction by forming a covalent bond with the pbr322 dna, which is an important DNA molecule in bacteria. The enzyme mechanism is not fully understood, but it has been shown that it can bind to Toll-like receptor 4 (TLR4), which is an innate immune system protein. This binding event activates TLR4, leading to the inflammatory response. 3-Hydroxy-4-nitrobenzaldehyde has shown efficacy against microglia cells and animal experiments have shown that this compound may be useful for reducing pain after surgery or injury.