Building Blocks

Versatile small molecule scaffold

1,2,5,6,7,8-Hexahydroquinoxalin-2-one is a stimulant that has been shown to be effective for the prophylaxis and/or treatment of diabetes. It is also a prophylactic agent for the prevention of pyrazinone. This drug has been shown to stimulate insulin secretion from pancreatic beta cells in vitro. 1,2,5,6,7,8-Hexahydroquinoxalin-2-one stimulates the release of insulin by stimulating exocytosis and inhibiting vesicle fusion in response to glucose. It can also inhibit or stimulate the release of insulin in response to other stimuli such as amino acids and fatty acids.

Versatile small molecule scaffold

Tributyl(methoxymethyl)stannane is a synthetic organo-tin compound that has antifungal, antiviral, and antibacterial properties. It is also used in the treatment of idiopathic pulmonary fibrosis, hepatitis, cirrhosis, heart disease, and scleroderma. Tributyl(methoxymethyl)stannane inhibits the synthesis of proteins by binding to the 30S ribosomal subunit through a number of mechanisms. It has been shown to inhibit the growth of many fungi including those that cause athlete's foot and ringworm. Tributyl(methoxymethyl)stannane also shows some promise as an anti-inflammatory agent.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Bromo-4-isopropylpyrimidine is an alkylating agent that forms a C–N bond with acylation reactions. This compound can be used as a substrate for acylation reactions and is catalyzed by copper or silver salts. 5-Bromo-4-isopropylpyrimidine reacts with carboxylic acids to form esters, which are useful for the synthesis of compounds such as corticosteroids. 5-Bromo-4-isopropylpyrimidine is also used in biomolecular chemistry to form acetal bonds with alcohols and other organic compounds.

Versatile small molecule scaffold

2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid is a molecule that binds to tropomyosin, a protein that is involved in the contraction of skeletal and cardiac muscles. This drug has been shown to inhibit the growth of viruses by binding to their nucleic acids and preventing them from replicating. It also inhibits chloride ion channels, leading to an increase in intracellular calcium levels. 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid is used as a cytotoxic agent against tumor cells in cell culture experiments and transgenic animals. The drug can be used for the treatment of prostate cancer, breast cancer, and colon cancer.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold