Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

1H-Benz[g]indazole, 4,5-dihydro- is a research chemical that has various applications in the field of biochemistry and pharmaceutical research. It is commonly used as a precursor for the synthesis of fatty acids and cytidine derivatives. This compound has shown potential therapeutic effects in the treatment of thrombocytopenia, a condition characterized by low platelet count. Additionally, 1H-Benz[g]indazole, 4,5-dihydro- is often utilized as a reactant in the production of other chemicals such as anhydrous citric acid, choline derivatives, larotaxel, nintedanib, and saccharin sodium. Its reactivity with hydrogen ions and chloride ions makes it suitable for various chemical reactions and processes. Researchers and scientists rely on this compound for its versatility and reliability in their experiments and studies.

4-Allyl-3-thiosemicarbazide is a copper complex that inhibits the growth of cancer cells. Copper chloride is an important catalyst for this reaction. The coordination geometry of the copper ion and the structure of the product are key factors in determining its cytotoxicity. This compound has been shown to have significant cytotoxicity against a variety of cancer cell lines, including leukemia, lymphoma, breast, prostate, lung, pancreatic and colon cancer cells. 4-Allyl-3-thiosemicarbazide is also able to inhibit kinesin by binding to its ATPase site and preventing it from transporting cargo along microtubules.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

6-Aminohexanoic acid hydrochloride is a serine protease inhibitor that is used as a medicinal preparation. It is an amino acid with a carbonyl group, which in the presence of metal ions can act as a nucleophile. 6-Aminohexanoic acid hydrochloride has been shown to inhibit the activity of HIV and other viruses, which may be due to its ability to bind viral proteins and inhibit their function. This drug also inhibits the activity of serine proteases, including chymotrypsin and trypsin.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-2-methylpropan-2-yl)benzene is an organic solvent that has a hydrogen bond. It is used in the synthesis of malonic acid and kinetic studies. This solvent has been shown to react with chloride to form 1,2-dibromochloromethane. The reaction rate for this reaction is affected by the presence of other halides, such as iodine and bromine. 1-Bromo-2-methylpropan-2-yl)benzene can also be used as a polymerization inhibitor.

2,5-Dioxopyrrolidine-1-carbonitrile is a ligand that binds to boronic acids and is used in the synthesis of drug molecules. The synthesis of 2,5-dioxopyrrolidine-1-carbonitrile requires the reaction of a pyridine ring with an aryl boronic acid, followed by hydrolysis to release the lactam. This synthetic process can be modified to produce amines.