Building Blocks

Versatile small molecule scaffold

8-Bromonaphthalene-1-carboxylic acid is an organic compound with the chemical formula C6H4BrO2. It is a white solid that is soluble in water, methanol, and ethanol. 8-Bromonaphthalene-1-carboxylic acid can be synthesized by hydrolysis of ethyl esters of naphthalene with alkali or sulphonation. The yields are usually low (25%). The product can also be made via the diazotization of naphthalenes in the presence of sodium azide to form naphthamide, which then reacts with bromine to form 8-bromonaphthalene-1-carboxylic acid. 8-Bromonaphthalene carboxylic acid has been used as a nucleophile in organic synthesis for conjugate addition reactions.

Versatile small molecule scaffold

3-Iodo-2-propynol is a microbicidal agent, which belongs to the group of phenyl substituted alkylthio compounds. It is active against acarids and reactive with metal ions and organic solvents. 3-Iodo-2-propynol has been shown to have a high microbicidal activity against microorganisms such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The chemical structure of 3-iodo-2-propynol can be described as a chlorinated derivative of 2-propenal.
3-Iodo-2-propynol is an ester hydrochloride with the molecular formula CHClNO that was synthesized in 1885 by A. Wurtz and C. Perkin. The chemical properties of this compound are similar to those of phenylethyl alcohol (PEA).

Cyclododecanol is a non-polar solvent that has been used in pharmaceutical preparations. Cyclododecanol is produced by the reaction of cyclododecanone with dodecanedioic acid, fatty acids, and hydrogen fluoride. The hydroxyl group of cyclododecanol reacts with piperazine to form a solid catalyst. This reaction solution can then be separated into two layers using a section: the lower layer contains cyclohexane and the upper layer contains cyclododecanol. Cyclododecanol has a hydrophobic effect due to its lack of polar functional groups.
Molecular Weight: 150
Boiling Point:
Melting Point: -156°C
Solubility: Soluble (0.1 g/100 mL) in water
Flash Point:
Vapor Pressure:
Density: 0.988 g/mL at 25°C

1-(2-Methylpyridin-3-yl)ethanone is a ketone that can be synthesized using the reaction of methyl sulfone, benzyl sulfone, and sulphone. It has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis and has been used as a nonsteroidal anti-inflammatory drug (NSAID). 1-(2-Methylpyridin-3-yl)ethanone has also been shown to have analgesic effects in mice. This synthetic compound may be useful in treating inflammation, pain, and fever.

4-Thioureidobenzenesulfonamide (4-TBS) is a biochemical that interacts with β-catenin and inhibits the proliferation of cardiac and cancer cells. 4-TBS has been shown to have anticancer activity in vitro, but clinical studies have not yet been conducted. 4-TBS has been shown to inhibit the growth of testicular cancer cells in whole-cell patch-clamp assays. 4-TBS also has an inhibition potential for heart disease, which may be due to its ability to reduce carbonic anhydrase 2 levels.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(2-Hydroxyethoxy)benzenecarboxylic acid is a polyester that has been shown to have heat resistance, high mechanical properties, and biologic activity. It is prepared by the polymerization of benzoic acid with titanium and a catalyst. This polyester can be used as a structural material for implants or as a polymerization catalyst for polycondensation reactions. 4-(2-Hydroxyethoxy)benzenecarboxylic acid has an aliphatic group with 2 aliphatic groups and an aliphatic substance. It also exhibits catalytic activity in promoting the formation of polyesters from diols and diacids.

Versatile small molecule scaffold

2-[2-(Dimethylamino)ethoxy]ethanol (DMAEE) is a chemical that belongs to the group of amines. It is used as a surfactant in the form of ethylene diamine or metal hydroxides and has been shown to have transport properties. DMAEE's protonated form has been shown to adsorb on metal oxides, such as iron oxide, aluminum oxide, and titanium dioxide. This adsorption mechanism may be due to its cationic nature. DMAEE also reacts with nitrous acid in water to form an intermediate which can be oxidized by atmospheric oxygen. The reaction mechanism for this oxidation is not yet well understood.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(Dimethylamino)benzyl Alcohol is a chemical compound with the formula CH3(CH2)3NH2. It is used as an antibiotic drug and has been shown to have an average particle diameter of 80 nanometers, bulk polymerization, hydroxy group, and polymerization initiator. 4-(Dimethylamino)benzyl Alcohol has been shown to be effective against bacteria that are resistant to penicillin, ampicillin, erythromycin, or tetracycline. This chemical compound has FTIR spectra in the range of 400-4000 cm-1 and can be used for the synthesis of polymeric matrices in many applications.

Versatile small molecule scaffold

Versatile small molecule scaffold