Building Blocks

3-(2,5-Dimethylphenyl)propionic acid is a cytotoxic agent that belongs to the group of carboxamides. It is lipophilic and has been shown to be effective against colon tumor cells in vivo. 3-(2,5-Dimethylphenyl)propionic acid binds to DNA chains and inhibits cellular proliferation by inhibiting the synthesis of nucleic acids. This agent also inhibits the activity of topoisomerases I and II, which are enzymes that are necessary for DNA replication and transcription. 3-(2,5-Dimethylphenyl)propionic acid has been shown to have a high cytotoxic potency in vitro but low potency against cultured human cells.

Versatile small molecule scaffold

3-(2',3'-Dimethylphenyl)propionic acid is a prostaglandin compound that inhibits the production of vasoconstricting and vasodilating substances. It belongs to the class of amide, benzoic acid, and azacyclic compounds. The structural formula is CHCOOH. 3-(2',3'-Dimethylphenyl)propionic acid inhibits the response of cells to agonists such as histamine, serotonin, and bradykinin by binding to specific receptors on cell surfaces called integrins. This compound has been shown to have vasospastic effects in patients with Raynaud's phenomenon or other diseases involving vasospasm. 3-(2',3'-Dimethylphenyl)propionic acid also has thrombotic effects due to its inhibition of blood coagulation factors IIa and Xa.

Versatile small molecule scaffold

1,1,4,4-Tetraphenyl-1,3-butadiene is a chemical compound that is stable in air and water. It has been shown to be active against pluripotent cells which are the precursor of all cells in the body. 1,1,4,4-Tetraphenyl-1,3-butadiene has been used for a number of biochemical research studies and has been shown to have electrochemical properties as an electrode material. This compound also has high values for toxicological studies. It can be found in the atmosphere at low levels but can also be released into the environment from industrial sources such as electric arc furnaces or coal burning plants.

Versatile small molecule scaffold

2-Iso-butylcyclopentanone is a ketone that has triplet and singlet states with rate constants of 8.9x10 M/s and 0.003 M/s, respectively. It has been shown to undergo photoelimination reactions in the presence of acyclic or cyclic triplet sensitizers. 2-Iso-butylcyclopentanone also undergoes a rate-limiting step in the formation of an excited state, which is called the S1 state or triplet. This reaction can be followed by measuring the fluorescence spectrum of the compound using a spectrofluorimeter, which shows that it emits light at wavelengths of 333 nm and 395 nm.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold