Building Blocks

<p>Applications 4-Pyridinecarboxaldehyde, is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.<br>References Ulloora, Sh., et al.: Ehro. J. Med. Chem., 70, 341 (2013);<br></p>

<p>Applications α-Chlorophenylacetyl Chloride is a reagent used for dehydrohalogenation of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brady, W.T., et al.: J. Org. Chem., 45, 3525 (1980); Brady, W.T., et al.: J. Org. Chem., 45, 2025 (1980);<br></p>

<p>Applications 4,5-Dimethyl-3-isoxazolamine is an isoxazole derivative used in the preparation of a varitey of biologically active compounds such as selective ETA receptor antagonists.<br>References Murugesan, N. et al.: J. Med. Chem., 46, 125 (2003);<br></p>

<p>Applications 1,2-Dimethylisothiourea-HI (cas# 41306-45-0) is a useful research chemical.<br></p>

<p>Applications (±)-3-Heptanol, is a volatile components of various plants, and can be used as flavor and fragrance ingredients. It is also used as building block used for the synthesis of various chemicals. It is used for the preparation of biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, I., et al.: Bioorg. Med. Chem. Lett., 55 (18), 5889 (2012); Gibka, J., et al.: Zeszyty Naukowe - Politechnika Lodzka, 60, 65 (1998);<br></p>

<p>Applications 3,4,5-Trimethoxytoluene is a reagent for oxadiazolylindazole sodium channel modulators which are neuroprotective toward hippocampal neurons.<br>References Clutterbuck, L. A., et al.: J. Med. Chem., 52, 2694 (2009);<br></p>

<p>Applications 3,4,5-Trimethoxybenzoyl Chloride is used as a reagent in the synthesis of 2-methyl-8-(3,4,5-trimethoxybenzamido)-1,2,3,4-tetrahydroisoquinoline and its analogs which display great antihypertensive activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathison, I.W., et al.: J. Med. Chem., 16, 332 (1973)<br></p>

<p>Applications 2-Formylphenylboronic acid (cas# 40138-16-7) is a useful research chemical.<br></p>

<p>Applications Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.<br>References Ahmad, I. et al.: Bioorg. Med. Chem. Lett., 23, 1322 (2013); Rhee, H. et al.: Bull. Kor. Chem. Soc., 32, 2391 (2011);<br></p>

<p>Applications A useful synthetic intermediate. It is used as a reactant in synthetic preparation of chiral 2-carboxy cyclic ethers.<br>References Zhu, S., et al.: J. Am. Chem. Soc., 132, 16374 (2010);<br></p>

<p>Applications Diisopropyl Malonate is a disinfection byproduct of Isoprothiolane (I874300); a dithiolane pesticide commonly used in agriculture as a fungicide to control planthoppers and blast disease in rice plants.<br>References Chin, K.M.: Malay. Agric. J., 50, 221 (1975); Ikeda, Y. et al.: Biosci. Biotech. Biochem., 57, 288 (1993); Nakamura, H.: Rev. Plant Prot. Res., 10, 1 (1977); Reddy, A.P.K. et al.: Pesticide, 22, 21 (1988); Jinno, H., et al.: Arch. Toxicol., 71, 550 (1997)<br></p>

<p>Applications 2-Aminoimidazole Sulfate (cas# 1450-93-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications A phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori, et al.: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications 6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid γ-Lactone is an intermediate in the synthesis of neuraminidase inhibitors.<br>References Kunstmann, M.P., et al.: J. Am. Chem. Soc., 84, 4115 (1962);<br></p>

<p>Applications 1-​Bromododecane (n-Lauryl Bromide) is a reagent used in the synthesis of porous organic polymers.<br>References Zhao, Y. et al.: ACS Macro. Lett., 7, 300 (2018);<br></p>

<p>Applications 3-Ethylsalicylaldehyde is an intermediate in the synthesis of thiosemicarbazones, inhibitors of lysophosphatidic acid acyltransferase.<br>References PCT Int. Appl. (2015), WO 2015157242 A1 20151015. Johnston, E V., et al.: J. Org. Chem., 75, 4596 (2010);<br></p>

<p>Applications Cinnamyl Bromide acts as a reagent in the synthesis of Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keller, M., et al.: Eur. J. Med. Chem., 109, 13 (2016)<br></p>

<p>Applications 4-Bromophenylacetic Acid (cas# 1878-68-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Thiophenecarbonyl Chloride is used in the synthesis of substituted pyridines as selective and highly effective GPR119 agonists. It is also seen in the preparation of diuretics.<br>References Wu, Y. et al.: Bioorg. Med. Chem. Lett., 20, 2577 (2010); Plattner, J. et al.: J. Med. Chem., 27, 1016 (1984)<br></p>

<p>Applications 2-Butynoic Acid is used as a reagent in the synthesis of BMS 911543 (B596075); a potent JAK2 inhibitor used as a potential treatment for myeloproliferative disorders. 2-Butynoic Acid is also used in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs as anti-cancer agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fitzgerald, M.A., et al.: J. Org. Chem., 80, 6001 (2015); Ramanivas, T., et al.: Eur. J. Med. Chem., 92, 608 (2015)<br></p>