Réactifs synthétiques

<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>

<p>Applications L-2-Aminobutanol has potential application as an inhibitor of L-Fucosidases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blaser, A. et al.: Org. Lett., 2, 1733 (2000);<br></p>

<p>Applications A caffeine metabolite which showed high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>

<p>Applications tert-Butyl (R)-3-Aminopiperidine-1-carboxylate, is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Aβ42 production in both in vitro and in vivo.<br>References Kobayashi, T., et al.: Bioorg. Med. Chem. Lett., 24, 378 (2014);<br></p>

<p>Applications Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.<br>References Walker, D., et al.: Pediatr. Blood Cancer 60,616 (2013); Kang, M., et al.: J. Chemother., 24, 292 (2012); Lipshultz, S., et al.: New England J. Med., 35, 145 (2004)<br></p>

<p>Applications o-Chloranil is used as a reagent in the synthesis of fused triazolotriazines and triazolotriazepines which exhibit antibacterial activity. Also used as a reagent in the synthesis of nickel diimine catecholate charge-transfer complexes.<br>References Aly, A.A., et al.: J. Chem. Res., 35, 169 (2011); Kramer, W.W., et al.: Inorg. Chem., 53, 8825 (2014)<br></p>

<p>Stability Hygroscopic<br>Applications Cerivastatin is a competitive inhibitor of HMG-CoA reductase.<br>References Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996), Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996),<br></p>

<p>Applications Cytidine derivative.<br>References Ueda, T., et al.: Chem. Pharmaceut. Bull., 22, 2377 (1974),<br></p>

<p>Applications Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic.<br>References Harland, S.J., et al.: Cancer Res., 44, 1693 (1984), Smith, I.E., et al.: Cancer Treat. Rep., 69, 43 (1985), Lygidakis, N.J., et al.: Interferon Cytokine Res., 15, 467 (1995),<br></p>

<p>Applications N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.<br></p>

<p>Applications 1-(4-Methoxyphenyl)piperazine (cas# 38212-30-5) is a useful research chemical.<br></p>

<p>Applications Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.<br>References Moilanen, et al.: Eicosanoids, 1, 35 (1988), Kirchner, et al.: J. Pharmacol. Exp. Ther., 282, 1094 (1997), Liu, et al.: Eur. J. Pharmacol., 435, 153 (2002),<br></p>

<p>Applications Ammonium Tetrathiomolybdate is a classic building block for transition metal sulfide cluster compounds.<br></p>

<p>Applications Pregnenolone (P712200) derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>

<p>Applications (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol is proven to have amphetamine-like effects and is being used for recreational drug use. It is one of a new class of synthetic stimulants known as pipradol derivatives. It inibits neurite growth in PC12 cells which contributes to its neurotoxic effects. It is used as a reagent in the synthesis of (S)-duloxetine which is an antidepressant drug. It is used to prepare chiral Corey-Bakshi-Shibata catalyst which is used in organic synthesis.<br>References Coppola, M., et al.: Toxicol. Lett., 212, 57 (2012); Lee, S., et al.: B. Kor. Chem. Soc., 35, 1894 (2014); Kaizaki, A., J. Toxicol. Sci., 35, 375 (2010); Corey, E., et al.: J. Am Chem. Soc., 109, 5551 (1987);<br></p>

<p>Stability Very Hygroscopic<br>Applications EDTA calcium disodium salt (cas# 62-33-9) is a useful research chemical.<br></p>

<p>Applications Ulipristal acetate is a selective progesterone receptor modulator. Ulipristal acetate is used during pregnancy.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>

<p>Applications 2,3-Dihydrofuran is a dehydration product of tetrahydrofuran (THF). 2,3-Dihydrofuran is also used in the preparation of niologically active compounds such as antitumor agents.<br>References Kohlweyer, U. et al.: FEMS Microbiol. Lett., 186, 301 (2000); Li, J. et al.: Lett. Drug Design Disc., 9, 379 (2012);<br></p>

<p>Applications Cesium Carbonate is used in the preparation of prodrugs based upon phosphonooxymethyl as HIV-1 attachment inhibitors. Also used in the synthesis of dodecahedral nanocrystals as effective antibacterial agents.<br>References Leahy, D. et al.: Org. Proc. Res. Dev., 17, 1440 (2013); He, J. et al.: Dalton Trans., 42, 15637 (2013);<br></p>

<p>Applications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)<br></p>

<p>Applications 1,4-Dihydropyridine calcium antagonist with antihypertensive and diuretic effects. A potential candidate in the treatment of patients with renal parenchymal hypertension.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ohya, Y. et al.: Int. J. Clin. Pharmacol. Therap., 38, 304 (2000); Huh, W. S. et al.: Curr. Therap. Res., 61, 395 (2000); Katoh, M. et al.: Eur. J. Clin. Pharmacol., 55, 843 (2000);<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Furanone is a heterocyclic organic compound that is used widely in the synthetic preparation of pharmaceutical goods.<br>References Kim, H.K., et al.: Plant. Pathol. J., 28, 259 (2012); Nam, S., et al.: J. Agr. Food. Chem., 60, 9097 (2012); Durchschein, K., et al.: Eur. J. Org. Chem., 2012, 4963 (2012);<br></p>

<p>Applications Hydrobromic acid is a strong acid that is used in conjunction with Phenol (P318005) to carry out rapid cleavage of sulfonamides. Hydrobromic acid is primarily used in chemistry to produce inorganic bromides, and is also used in isomerization reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aida, T., et al.: Tetrahedron Lett., 14, 39 (1973); Elliott, J., et al.: J. Agr. Food Chem., 8, 111 (1960); Nozaki, K. &amp; Ogg Jr., R.: J. Am. Chem. Soc., 63, 2583 (1941); Snyder, H. &amp; Geller, H.: J. Am. Chem. Soc., 74, 4864 (1952)<br></p>

<p>Applications Mitoquinol is an antioxidant mitochondrial-targeted coenzyme Q analog with neuroprotective effects.<br>References Fink, B.D., et. al.: J. Pharmacol. Exp. Ther., 342, 709 (2012); Hobbs, C.E., et. al.: Pediatr. Int., 50, 481 (2008)<br></p>

<p>Stability Hygroscopic<br>Applications Bafilomycin A1 is a specific inhibitor of vacuolar type H+-ATPase (V-ATPase) in animal cells, plant cells and microorganisms.<br>References Bownman, E., et al.: PNAS, 85, 7972 (1988); Umata, T., et al.: J. Biol. Chem., 265, 21940 (1990); Saurin, A., et al.: Biochem.<br></p>

<p>Applications YM155 is a novel small-molecule survivin suppressant that suppressed expression of survivin and induced apoptosis in PC-3 and PPC-1 human HRPC. cell lines. Potent Survivin Inhibitor.<br>References Takhito, N., et al.: Cancer. Res., 67, 8014 (2007); Kita, A., et al.: J. Pharmacol. Exper. Therap., 343, 178 (2012); Kumar, B., et al.: Molec. Cancer. Therap., 11, 1988 (2012);<br></p>

<p>Applications Copper Dipropanoate is a reagent in the preparation of superconductors and semiconductors.<br>References PCT Int. Appl. (2015), WO 2015071709 A1 20150521;<br></p>

<p>Applications (+)-Sparteine (cas# 492-08-0) is a useful research chemical.<br></p>

<p>Applications Cilastatin prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. It is an antibacterial adjunct.<br>References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983); Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983); Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983);<br></p>

<p>Stability Light Sensitive<br>Applications α-Methacrylic acid is used in chemistry as a stabilizing agent, forming a thin capping layer on the surface of nanoparticles. α-Methacrylic acid is also used as a surfactant, so that control is maintained during nanocrystal growth. α-Methacrylic acid is also used as a chelating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peng, W., et al.: J. Cryst. Growth, 279, 454 (2005); Qu, S., et al.: Appl. Phys. Lett., 80, 3605 (2002); Zhao, G., et al.: Phys. C: Supercond., 468, 2317 (2008)<br></p>

<p>Applications Calcium Oxide is an exothermic reagent used in the synthesis of polymers and ceramics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lee, S. et al.: Mat. Lett., 175, 135 (2016); Dae, J. et al.: J. App. Polym. Sci., 133, (2016);<br></p>

<p>Applications A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>

<p>Applications Potassium Ferrocyanide Trihydrate functions in the DNA-binding, cytotoxicity, cellular uptake, apoptosis and photocleavage studies of ruthenium(II) complexes.<br>References Deepika, N., et al.: J. Photochem. Photobiol., B: Biol., 160, 142 (2016)<br></p>

<p>Applications Potassium Hydroxide is inorganic compound and strong base with many applications. It is used in the production of biodiesel. Potassium Hydroxide is also used in the manufacture of soaps.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nadarajan, R., Ismail, R.: J. Surfactants Deterg., 14, 463 (2011); Hajek, M., et al.: Fuel, 96, 85 (2012);<br></p>

<p>Applications PYR-41 is the cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.<br>References Yang, Y., et al.; Cancer Res., 67, 9472 (2007); Ungermannova, D., et al.: J. Biomol. Screening, 17, 421 (2012)<br></p>

<p>Stability Moisture Sensitive<br>Applications 3-Glycidoxypropyltrimethoxysilane (cas# 2530-83-8) is a useful research chemical.<br></p>

<p>Applications 3-Acetopropanol is a substrate for alcohol dehydrogenase and is an intermediate in the synthesis of Didesethyl Chloroquine (D440960), a metabolite of Chloroquine.<br>References Ohkuma, S., et al.: J. Cell. Biol., 90, 656 (1981); Araki, N., et al.: J. Biol. Chem., 267, 10211 (1992); Projean, D., et al.: Drug Metab. Dispos., 31, 748 (2003); Traebert, M., et al.: Eur. J. Pharmacol., 484, 41 (2004)<br></p>

<p>Applications Amiloride Monohydrochloride Dihydrate is used as an inhibitor of 11β-hydroxysteroid dehydrogenases (11β-HSD) for treating alcohol use disorders.<br>References Sanna, P. et al.: PCT Int. Appl. (2017)<br></p>

<p>Applications Icatibant Acetate is a bradykinin B2 receptor antagonist that has been recently approved for treatment of acute attacks of hereditary angioedema (HAE).<br>References Greve, J., et al.: Int. J. Dermatol., 50, 1294 (2011); Cole, S.W., et al.: Ann. Pharmacother., 47, 49 (2013)<br></p>

<p>Applications (-)-α-Kainic Acid Monohydrate is the monohydrated form of (-)-α-Kainic Acid (K135010); a naturally occurring neuroexcitatory chemical that is a selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.<br>References Wacker, D.A., et al.: Synlett, 503 (1997); Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Ampicillin. Orally active, semi-synthetic antibiotic; structurally related to penicillin. Antibacterial.<br>References Ivashkiv, E., et al.: Anal. Profiles Drug Subs., 2, 1 (1973), Campoli-Richards, D.M., et al.: Drugs, 33, 577 (1987), Sill, M. L., et al.: Antimicrob. Agents Chemother., 52, 1551 (2008),<br></p>

<p>Applications (S)-α,α-Bis[3,5-di(trifluoromethyl)phenyl]-O-(trimethylsilyl)pyrrolidine-2-methanol, is a diarylprolinol silyl ether organocatalyst. It is able to catalyze a variety of bond-forming reactions such as C-C, C-N, C-O, C-S, and C-Hal in high yields and excellent levels of enantiocontrol.<br>References Jensen KL, et al. Accounts of Chemical Research 45(2), 248-264, (2011);<br></p>

<p>Applications (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine is a Josiphos ligand.<br>References MacQueen, P., et al.: Chemistry - A European Journal, 21, 11006 (2015);<br></p>

<p>Applications (R)-2-Hydroxybutanoic acid (cas# 20016-85-7) is a useful research chemical.<br></p>

<p>Applications 4-Pyridylthioacetic Acid (cas# 10351-19-6) is a compound useful in organic synthesis.<br></p>

<p>Applications o-Acetyltoluene can be used as a reagent to prepare diaryl dihydropyrazoles as inhibitors of mitotic kinesin spindle protein (1). It is also used to synthesize aryl- and indolyl-cyanoaminopyridines with anti-inflammatory, analgesic, and antipyretic activities (2).<br>References (1) Cox, C., et al.: Bioorg. Med. Chem. Lett. (2005) 15, 2041 (2) Manna, F., et al.: Eur. J. Med. Chem. (1999) 34, 245-54<br></p>

<p>Stability Hygroscopic<br>Applications (R,R)-Labetalol Hydrochloride is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol Hydrochloride is also used as an antihypertensive.<br>References Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),<br></p>

<p>Applications Sodium selenite is used in reducing carcinogenesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Used for preparation of antidiabetic agents comprising antiinflammatory or analgesic drugs.<br>References Nemoto, H., et al.: J. Med. Chem., 38, 1673 (1995),<br></p>

<p>Stability Unstable in Solution, Air Sensitive<br>Applications An antirheumatic agent.<br>References Masutani, K., et al.: Clin. Nephrol., 70, 464 (2008), Kobata, Y., et al.: Modern Rheumatol., 19, 629 (2009), Oki, K., et al.: Inflam. Res., 58, 571 (2009),<br></p>

<p>Applications 1-(Bromomethyl)-2-nitrobenzene is a reagent used in the synthesis of 1,3,4-oxadiazole derivatives possessing a benzotriazole moiety leading to anticancer activity. Also used in the preparation of antifungal triazole derivatives.<br>References Zhang, S. et al.: Bioorg. Med. Chem., 21, 3723 (2013); Yu, S. et al.: Arch. Pharm. Res., 36, 1215 (2013);<br></p>

<p>Applications MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption.<br>References Arns, S., et al.: Bioorg. Medn. Chem., 20, 2131 (2012); Cusick, T., et al., J. Bone. Mineral. Rsch., 27, 524 (2013);<br></p>

<p>Applications Larotrectinib Sulfate is a potent and selective oral ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).<br>References Anon.: Cancer Discovery, 6, 4 (2016); Passiglia, F., et al.: Expert Opin. Investig. Drugs, 25, 385 (2016)<br></p>

<p>Applications A minor antimicrobial used in veterinary medicine.<br>References Dowling, P.M., et al.: Antimicrob. Ther. Vet. Med., 285 (2006), 4th Edition,<br></p>

<p>Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990), McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997), Pitt, B., et al.: Lancet, 355, 1582 (2000);<br></p>

<p>Applications Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis at 50-100µM.[Blebbistatin:a]D= -103 (c= 1.21 CHCl3)(-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-oneBlebbistatin is a selective inhibitor of nonmuscle myosin II; Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.<br>References Straight, A.F., et al.: Science, 299, 1743 (2003), Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2004), Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)<br></p>

<p>Applications Girard’s reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents.<br>References Mirzaei, H., et al.: J. Chrom. A, 1134, 122 (2007); Kanofsky, J.R., et al.: Photochem. Photobiol., 73, 349 (2001);<br></p>

<p>Applications It is an Olefin Metathesis Catalyst for cis-selective ring-opening metathesis polymerization and Z-Selective Olefin Metathesis.<br></p>

<p>Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)<br></p>

<p>Applications Antilipemic.<br>References Fuccella, L.M., et al.: Clin. Pharmacol. Ther., 28, 790 (1980), Lovisolo, P.P., et al.: Pharmacol. Res. Commun., 13, 151 (1981), Aktories, K., et al.: Arzneim.-Forsch., 33, 1525 (1983), Boatman, P., et al.: J. Med. Chem., 51, 7653 (2008), Rigazio, S., et al.: Am. J. Physiol., 295, E413 (2008),<br></p>

<p>Applications Gonadorelin Acetate is used in various agricultural and biological studies. It was used in the study of ovulation synchronization in dairy cows.<br>References Pursley, J., et al.: Theriogenology, 44, 915 (1995).<br></p>

<p>Stability Air Sensitive, Hygroscopic<br>Applications N-1-Naphthylethylenediamine Dihydrochloride, is an organic building block used for the chemical synthesis. It can also be used as highly selective organic fluorescent probe for azide ion.<br>References Sahana, A., et al.: Analyst , 137, 1544 (2012);<br></p>

<p>Impurity Atomoxetine EP Impurity E<br>Applications (S)-(+)-Mandelic Acid (Atomoxetine EP Impurity E) is an antiseptic (urinary).<br>References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007), Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009),<br></p>

<p>Applications Synthetic keto-derivative of Petromyzonol (P293500), a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). May be used to study the biochemical characteristics of these and other compounds containing the allocholic acid ring nucleus.<br>References Haslewood, G., et al.: Biochem. J., 114, 179 (1969); Sorensen, P.W., et al.: J. Gen. Physiol., 105, 569 (1995), Krasowski, M., et al.: Mol. Endocrinol., 19, 1720 (2005),<br></p>

<p>Applications 3-Mercaptopropionic Acid (cas# 107-96-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Diammonium salt of Phosphoric Acid, used in various chemical processes as a phosphorylating compound. Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties.<br>References Ezhova, Z. et al.: Russ. J. Inorg. Chem., 58, 1177 (2013); Wu, Y. et al.: Asian J. Chem., 25, 5881 (2013);<br></p>

<p>Applications Lead(II) Nitrate, is toxic, an oxidising agent, and is categorized as probably carcinogenic to humans . It is shown to inhibit bacterial oxidation of ferrous iron in sulfate-rich systems. Other Lead(II) Nitrate applications include use as a heat stabilizer in nylon and polyesters, as a coating for photothermographic paper, and in rodenticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hongmei, w., et al.: J Hazard. Mat., 244, 718 (2013); Greenwoos, N. N., et al.: 388 (1997); Pauley, J. L., et al.: J. Amer. Chem. Soci., 76 (16), 4220 (1954);<br></p>

<p>Applications Reagent used in the preparation of carbonic anhydrase inhibitors.<br></p>

<p>Applications 2-Methylisoborneol solution - (CAS# 2371-42-8) is a useful research chemical compound.<br></p>

<p>Applications Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.<br>References Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)<br></p>

<p>Applications Vasodilator, used in treatments for angina.<br>References Miyamoto, S., et al.: Toxicol. Mech. Method., 19, 477 (2009), Perez-Reyes, E., et al.: J. Pharmacol. Exper. Ther., 328, 621(2009), Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009),<br></p>

<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>

<p>Applications N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.<br></p>

<p>Applications Chiral derivative of 3-Hydroxyisobutyrate.<br>References Waldmann, H., et al.: Bioorg. Med. Chem., 2, 477 (1994), Vonstein, V., et al.: J. Bacteriol., 177, 4540 (1995),<br></p>

<p>Applications A product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>

<p>Applications 2-Chloroethyl isocyanate is used as a reagent and building block in chemical synthesis. In particular, it is used in the preparation of functionalized aminobenzoboroxoles which are potential anti-cancer agents and also the synthesis of 3-(2-chloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one which also exhibit antiproliferative activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Suman, P., et al.: J. Organomet. Chem., Ahead of Print (2015); Maggio, B., et al.: Eur. J. Med. Chem., 96, 98 (2015)<br></p>

<p>Applications Isotope labelled 1,3-Propanediol, a common organic reagent used in the synthesis of polymers and used in industrial organic chemistry for the synthesis of lubricants, foods, medicines and cosmetics.<br>References Sun, Y. et al.: Bioproc. Renew. Res. Commod. Bioprod., 289 (2014);<br></p>

<p>Applications (1R,3S)-Camphoric Acid is used primarily as a reagent in syntheses of crystalline structures. It is used in the preparation of polymeric transition metal dipyridylamine D-camphorate complexes.<br>References Blake, K. et al.: Crys. Growth Des., 12, 5215 (2012);<br></p>