Réactifs synthétiques

Applications 6-Bromopurine is a brominated derivative of purine used in various organic syntheses. Used in the synthesis of several benzo-fused scaffolds with purine or pyrimidine moietes which display antitumor and anticancer properties.
References Morales, F. et al.: Eur, J. Med. Chem., 76, 118 (2014); Cushing, T. et al.: J. Med. Chem., 58, 480 (2015); Jansen, R., et al.: Clin. Biochem., 38, 362 (2005),

Applications 15-Crown-5 is a catalyst used in the synthesis of organic molecules and lanthanide complexes. It can induce cytotoxicity and oxidative stress markers in WI38 cells. Studies show that 15-Crown-5 is also an effective chelating agent used for removing cesium in cesium-exposed mice.
References Li, L. et al.: J. Organometal. Chem., 794, 231 (2015); Gonzalez-Bello, C. et al.: J. Am Chem. Soc., 137, 9333 (2015); Llobet, J.M., et al.: Metal Ions Biol. Med., 4, 487 (1996)

Applications Scandium Triflate is an important catalyst used in Friedel-Crafts acylation, Baylis-Hillman reaction and other carbon-carbon bond forming reactions.
References Kawada, A., et al.: Synlett, 7, 545 (1994); Aggarwal, V., et al.: J. Org. Chem., 63, 7183 (1998);

Applications Methyl (R)-3-Hydroxybutyrate, a derivative of 3-hydroxybutyric acid, has inhibitory effects on cell apoptosis which is mediated by signaling pathways related to the elevation of cytosolic Ca2+ concentration. Also a potential effective neutral protective agent.
References Xiao, X.Q., et al.: Biomaterials, 28, 3608 (2007)

Applications Foretinib (GSK1363089) is an ATP-competitive inhibitor of hepatocyte growth factor (HGF) and Vascular endothelial growth factor (VEGF) Receptor Tyrosine Kinases.
References Qian, F., et al.: Cancer Res., 69, 8009 (2009); Eder, J., et al.: Clin. Cancer Res., 16, 3507 (2010)

Stability Moisture Sensitive
Applications Zinc Di[bis(trifluoromethylsulfonyl)imide] is a reactant used in the assembly of pyrene-based Schiff base MII4L6 architectures.
References Ronson, T. et al.: J. Am. Chem. Soc., 137, 14502 (2015); Riddell, I. et al.: Chem. Sci., 6, 3533 (2015);

Stability Hygroscopic
Applications A potent and discriminating antagonist for AMPA binding sites.
References HonorÈ, T., et al.: Science, 241, 701 (1988), Gill, et al.: Brain Res., 580, 35 (1992), Pook, et al.: Br. J. Pharmacol., 108, 179 (1993)

Applications An Aurora kinase inhibitor, used to treat patients with chromic myeloid leukemia. It is a COVID19-related research product.
References Fancelli, D., et al.: J. Med. Chem., 49, 7247 (2006), Carpinelli, P., et al.: Mol. Canc. Ther., 6, 3158 (2007), Coumar, M., et al.: J. Med. Chem., 52, 1050 (2009),

Applications 5-Chloro-2-methylaminopyridine is used in the preparation of aminosulfuranes with N-heterocyclic groups.
References Pashinnik, V.E. et al.: Ukr. Khim. Zhur., 73, 45 (2007);

Applications 4-Iodophenol is used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients. Also it is used in the synthesis of agonists towards the estrogen β receptor.
References Bi, S. et al.: Chem. Comm., 49, 3452 (2013); Demkowicz, S. et al.: RSC, Adv., 3, 3697 (2013);

Applications Magnesium Bromide Hexahydrate is an inorganic salt used in the synthesis of superconductors and nanowires. Also present in polymer nanocomposites to improve conductivity.
References Alam, M. et al.: Polym. Int., 63, 1465 (2014); McDonald, T. et al.: J. Am. Chem. Soc., 135, 7056 (2012);

Applications 4-Nitro-benzeneethanol is a useful synthetic intermediate. It can be used to synthesize N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptor. It can also be used to prepare 2-aza-2'-deoxyinosine-containing oligodeoxyribonucleotide duplexes.
References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012); Acedo, M., et al.: J. Org. Chem., 60, 6262 (1995)

Applications Zinc Acetate is used in biological studies and pharmacological activity of motexafin gadolinium disruptions of zinc metabolism in human cancer cell lines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Magda, D., et al.: Cancer Res., 65, 3837 (2005);

Applications 3-Ethylpentane (cas# 617-78-7) is a useful research chemical.

Applications 1,2,4,5-BENZENETETRACARBOXYLIC ACID (cas# 89-05-4) is a useful research chemical.