Alcools

<p>Applications Glycerol formal is used as a dye emulsifier and as a cosolvent for drug delivery.<br>References Sun, M., et al.: Drug Devel. Ind. Pharm., 37, 986 (2011); Greenbaum, L., et al.: Cancer Res., 43, 2584 (1983)<br></p>

<p>Applications cis-4-Decen-1-ol is a reactant in the synthesis of epoxyisoprostanes as antiinflammatory agents.<br>References Egger, J., et. al.: Angew. Chem. Int. Edit., 52, 5382 (2013)<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Stability Air Sensitive<br>Applications Thiol-PEG2-acid (cas# 1379649-73-6) is a useful research chemical.<br></p>

<p>Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.<br>References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);<br></p>

<p>Applications 1-(hydroxymethyl)cyclopentan-1-ol (cas# 74397-18-5) is a useful research chemical.<br></p>

<p>Applications 4-Pentyn-1-ol is an alkyne alcohol that is used as an initiator in ring-opening polymerization reactions. 4-Pentyn-1-ol is capable of undergoing cyclosisomerization, and is also used as a reactant in the synthesis of (+)-Serinolamide A, a cannabinoid CB1 receptor agonist.<br>References Gao, Y., et al.: Tetrahedron Lett., 54, 6511 (2013); Liao, R., et al.: Proc. Nat. Acad. Sci., 107, 22523 (2010); Miranda, P., et al.: Org. Lett., 5, 1979 (2003); Xu, N., et al.: Macromol. Chem. Phys., 208, 730 (2007)<br></p>

<p>Applications 1-Nonanol is an chain fatty acid alcohol that naturally occurs in oil of orange. 1-Nonanol is used in the manufacture of artificial lemon oil.<br>References Tabilio, M.R., et al.: Food Chem., 140, 375 (2013); Thomas, C., et al.: Food. Chem., 139, 432 (2013);<br></p>

<p>Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. &amp; Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)<br></p>

<p>Applications 2,5-Dimethoxythiophenol is a thiophenol derivative used in the preparation of dihydrofolate reductase inhibitors and potential antitumor agents.<br>References Gangjee, A. et al.: J. Med. Chem., 52, 4892 (2009); Gangjee, A. et al.: Biiorg. Med. Chem., 18, 953 (2010);<br></p>

<p>Stability Light Sensitive<br>Applications 9-Decen-1-ol can be used to synthesize terminal olefins or generate epoxides.<br>References Blackwell, H. E., et al., J. Am. Chem. Soc. 122, 58 (2000); Coperet, C., et al.: Chem. Commun 16, 1565 (1997)<br></p>

<p>Applications (±)-3-tert-Butoxy-1,2-propanediol is a diesel fuel additive.<br>References Frusteri, F., et al.: Appl. Catal., 367, 77 (2009)<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>

<p>Applications 3-Hydroxybenzyl Alcohol, is shown to have antioxidant and free radical scavenging activity.<br>References Dhiman, S., et al.: Chemi-Bio. Interac., 182, 119 (2009); Alfaro, C., et al.: Mutation Res., 539(1-2), 187 (2003);<br></p>

<p>Applications 1-Adamantanemethanol is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.<br>References Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013); Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012); Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)<br></p>

<p>Applications 3-(Nitroamino)propanol is an analog of 2-(Nitroamino)ethanol (N491750), which is used in the preparation of N-alkylnitratoethyl nitramines as energetic plasticizers for explosives and propellants.<br></p>

<p>Applications 3-(2-Pyridyl)-2-propen-1-ol (cas# 131610-03-2) is a useful research chemical.<br></p>

<p>Applications 1-Nonadecanol (cas# 1454-84-8) is a useful research chemical.<br></p>

<p>Applications 2-(Tetrahydro-2H-pyran-3-yl)ethanol (cas# 1050493-77-0) is a useful research chemical.<br></p>

<p>Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.<br>References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976)<br></p>

<p>Applications (S,S)-2,3-Butanediol is the (S,S)-isomer of 2,3-Butanediol (B690020), a naturally occurring compound found in cocoa butter.<br>References Wang, Yu., et al.: J. Biological. Chem., 289, 6080 (2014); Cheng, C., et al.: J. Org. Chem., 78, 8562 (2013);<br></p>

<p>Applications 4-(phenylsulfanyl)phenol (cas# 5633-55-6) is a useful research chemical.<br></p>

<p>Applications 4-Amino-2-isopropylphenol is a building block used in the preparation of benzoate and benzamide derivatives as FXR antagonists.<br>References Song, K., et al.: Bioorg. Med. Chem., 23, 6427 (2015);<br></p>

<p>Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)<br></p>

<p>Applications 4-​Bromo-​3-​methyl-2-buten-1-ol is an intermediate in the synthesis of 2-[(4-Bromo-3-methyl-2-buten-1-yl)oxy]tetrahydro-2H-pyran (B681855), which is a tetrahydropyran protected intermediate used in the synthesis of L-Cysteine derivatives.<br></p>

<p>Applications 1-Butanol is a common chemical reagent used in biodiesel production. Also it has been used in the study the polarization of vapor-deposited 1-butanol films (1) as well as in the preparation of bioavailable CB1 antagonists (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gavra, I. et al.: J. Chem. Phys. 2017 Mar 14;146(10):104701.2. Röver, S. et al.: J. Med. Chem. 2013 Dec 27;56(24):9874-96.<br></p>

<p>Stability Dimerizes Readily - Store Under Inert Atmosphere<br>Applications 4-Mercaptobenzyl Alcohol, 90% (cas# 53339-53-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-(2-Pyridylazo)resorcinol (cas# 1141-59-9) is a useful research chemical. Dyes and metabolites.<br></p>

<p>Applications Di-sec-butylphenol, mixture of isomers, predom. 2,6-isomer (cas# 5510-99-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methoxy4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzenemethanol, is prepared synthetically from vanillin (V097500) with an intermediate of methoxy-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzaldehyde (M269710).<br>References Gowravarm, S. et al.: Adv. Synth. Catal., 343, 169 (2001)<br></p>

<p>Applications 2-(3-Aminophenyl)ethanol is a useful compound for the synthesis of indolines and dihydrobenzofurans via iron and copper-catalyzed iodination and cyclization.<br>References Henry, M. C., et al.: J. Org. Chem., 84, 346 (2019)<br></p>

<p>Applications (2R)-2-(dimethylamino)propan-1-ol (cas# 55197-05-2) is a useful research chemical.<br></p>

<p>Applications 1-(3,5-Bis(benzyloxy)phenyl)pentan-2-ol is an intermediate for the synthesis of 2''-Hydroxycannabidiol (H824820), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 2''-Hydroxycannabidiol can be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Applications N-(2-Hydroxyethyl)tetracosanamide acts as a crude oil emulsifier.<br>References Zhiqiang, J., et al.: Fami Zhu Shen., 5 (2016)<br></p>

<p>Applications 2,5-Dimethoxybenzyl Alcohol can be used as a self-indicating standard for the determination of organolithium reagents<br>References Winkle, M.R. et al.: J. Chem. Soc. Chem. Comm., 3, 1980 (1980):<br></p>

<p>Applications cis-3-Octen-1-ol (cas# 20125-84-2) is a useful research chemical.<br></p>

<p>Applications 1,1,2,2-tetraphenylethane-1,2-diol (cas# 464-72-2) is a useful research chemical.<br></p>

<p>Applications 3-Furanmethanol (cas# 4412-91-3) is a useful research chemical.<br></p>

<p>Applications Methanol-d is an isotope labelled version of Methanol (M276585). Methanol (M276585) is a common chemical reagent in organic synthesis participating in a variety of reactions. Methanol is a bioactive component with antimicrobial activities.<br>References Keskin, D., et al.: Fresenius Env. Bull.., 27, 7991 (2018)<br></p>

<p>Applications 3,​7-​Dimethyl-​1-​octanol is a useful organic reactant/reagent.<br>References Dantignana, V., et al.: ACS Cent Sci., 3, 1350-58 (2017); Jana, S., et al.: Org, Lett., 19, 746-49 (2017);<br></p>

<p>Applications 4,4-dimethylpentan-2-ol (cas# 6144-93-0) is a useful research chemical.<br></p>

<p>Applications 1-Propanethiol-SD (CAS# 64071-73-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-(Decyloxy)phenol is used as a reactant in the preparation of liquid crystal halogen-bond dimers with substituted pyridines.<br>References Bruce, D., et al.: Chem-Eur J., 16, 9511 (2010)<br></p>

<p>Applications (1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP<br>References Kündig, E., et al.: Helv. Chim. Acta, 77, 421 (1994); Aramoto, H., et al.: J. Org. Chem., 74, 628 (2009)<br></p>

<p>Applications Asenapine Phenol is a research reagent used to study effect on DNA oxidation<br>References Bao, L.L., et al.: ChemMedChem, 11, 1617 (2016)<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 2-(Ethylthio)ethanol is used to prepare aryldihydropyrimidinones as inhibitors of fatty acid transporter FATP4.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blackburn, C., et al.: Bioorg. Med. Chem. Lett., 16, 3504 (2006)<br></p>

<p>Applications 2-Amino cyclopentanol<br></p>

<p>Applications (2R)-1-(9H-Purin-6-ylamino)-2-propanol is a reagent for the synthesis of tenofovir disoproxil fumarate, a medication for the treatment of hepatitis B and to prevent and treat HIV/AIDS.<br>References Yan, N., et al.: Jingxi Huagong, 31, 983 (2014); Ripin, D. H. B., et al.: Org. Process Res. Dev., 14, 1194 (2010)<br></p>

<p>Applications 4-Aminophenethyl Alcohol, is a building block that can be used in the synthesis of various compounds, such as in synthesis of 4-aminostyrene, and in functionalization of graphene nanoplatelets.<br>References Li L, et al.Polymer Journal 33(4), 364-370; Hagiwara T, et al. Macromolecules 24(26), 6856-6858, (1991);<br></p>

<p>Applications 2,3-Dimethoxyphenol (cas# 5150-42-5) is a useful research chemical.<br></p>

<p>Applications 2-{[2-(Dimethylamino)ethyl]methylamino}ethanol is a reagent in the preparation of diamino(aminoalkoxy)quinazolines.<br>References Liu, F., et al.: J. Med. Chem., 53, 5844 (2010);<br></p>

<p>Applications 2-Tributyltin-allyl-1-ol (cas# 84666-30-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Cyclopropylethanol is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, 2-Cyclopropylethanol is also used to synthesize potent 15-Hydroxyprostaglandin dehydrogenase inhibitors, which ultimately minimize excessive scarring of wounds.<br>References Choi, D., et al.: Bioorg. Med. Chem., 21, 4477 (2013); Chorvat, R., et al.: J. Med. Chem., 28, 194 (1985);<br></p>

<p>Applications 2-Ethyl-3-butyn-1-ol is used as an additive in the synthesis of liquid crystal display adhesive.<br>References Ding, A., et al.: Faming Zhuanli Shenqing 5pp. Patent 2015 CODEN:CNXXEV;<br></p>

<p>Stability Unstable in aqueous media<br>Applications 1H-indazol-1-ylmethanol (cas# 1006-29-7) is a useful research chemical.<br></p>

<p>Applications 2-(2-Cyclopenten-1-yl)-phenol is an intermediate used in the synthesis of (S)-Penbutolol Sulfate (P220505), which is an isomer of Penbutolol (P220500), a β-adrenoceptor antagonist. Antihypertensive.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>

<p>Applications 2-Cyclohexen-1-Ol (cas# 822-67-3) is a useful research chemical.<br></p>

<p>Applications (S)​-​(-​)​-​1-​Phenyl-​1-​propanol is a building block used in the synthesis of inhibitors of steroid 11-β hydroxylation in the adrenal cortex related to androgen production in the fetus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zolle, I. et al.: J. med. Chem., 51, 2244 (2008);<br></p>

<p>Applications 4-(2,4,4-trimethylpentan-2-yl)benzene-1,2-diol (cas# 1139-46-4) is a useful research chemical.<br></p>

<p>Applications Cyclohexane is a general organic chemical solvent. It is also used as a precursor to the synthesis of nylon.<br>References Hiroshi O. et al.: J. Memb. Sci., 105, 51 (1995); Rekharsky, M.V. et al.: J. Am. Chem. Soc., 124, 12361 (2002);<br></p>

<p>Applications (S)-3-Aminobutan-1-ol can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity.<br>References Johns, B. et al.: J. Med. Chem., 56, 5901 (2013);<br></p>

<p>Applications 4-Hexadecyloxyphenol is used as a reactant in the enzyme-mediated two-dimensional polymerization of aromatic derivatives on a Langmuir Trough.<br>References Bruno, F., et al.: Ind. Eng. Chem. Res., 34, 4009 (1995)<br></p>

<p>Stability Volatile<br>Applications 3-Butyn-1-ol is an unsaturated alcohol that is used as a reagent to synthesize Kainic acid (K135000), a neuroexcitatory and neurotoxic analogue of glutamate that is utilized as a means to selectively lesion neuronal cell bodies. 3-Butyn-1-ol is also an important intermediate to prepare a variety of natural products in food and cosmetic industries.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, J. &amp; Whiting, M.: J. Org. Chem., 68, 6160 (2003); Ben-Ari, Y., et al.: Brain Res., 165, 3362 (1979); Olney, J., et al.: Brain Res., 77, 507 (1974); Yu, X., et al.: Org. Prep. Proc. Int., 38, 467 (2006)<br></p>

<p>Applications 1,8-Octanediol is used in the synthesis of polymers polyesters and polyurethane.<br>References David, F., et al.: Biomacromolecules, 11, 690 (2010)<br></p>

<p>Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.<br></p>