Amines

<p>1-(3-Aminopropyl)-2-pyrrolidinone is a chemical compound that has been used as a chemotherapeutic treatment for heart disease and polyamine oxidase deficiency. The compound has also been shown to have a direct effect on the synthesis of fatty acids in the body, which may lead to the development of new treatments for diabetes. 1-(3-Aminopropyl)-2-pyrrolidinone can be formulated into conjugates with other molecules, such as chloride ions or fatty acids, in order to target specific cells or tissues. This method of delivery is efficient and has been shown to be able to cross the blood-brain barrier. 1-(3-Aminopropyl)-2-pyrrolidinone is an amino acid derivative that contains an aminoguanidine functional group. Aminoguanidine inhibits polyamine oxidase activity in vitro by reacting with the carbonyl group at position C</p>

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<p>1-Aminononadecane is a monolayer, which is a type of thin film that consists of two layers of molecules. It consists of fatty acids, which are long-chain carboxylic acid molecules, and particle, which is the smallest part of a substance. 1-Aminononadecane has been shown to be biocompatible with cells when mixed with amines, such as amino acids and proteins. The film also has phase transition temperature between -20°C and +100°C, viscosity values that range from 10-6 to 10-1 Pa·s for polymer films (10 Pa·s for pure 1-aminononadecane), reaction vessel where it is made in an organic solvent or water at neutral pH, and chemical structures that include both aromatic hydrocarbons and unsaturated alkyl chains.</p>

<p>Please enquire for more information about Biotinyl-epsilon-aminocaproyl-D-Phe-Pro-Arg-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Amino-2-methoxy-4-methylpyridine is a small molecule that inhibits bromodomains. Bromodomains are protein domains that bind to acetylated lysine residues on histones. 5-Amino-2-methoxy-4-methylpyridine binds to the bromodomain, preventing the acetylated lysine residues from binding with other proteins and inhibiting transcription. This drug has been shown to be effective in treating prostate cancer by interacting with the androgen receptor. 5-Amino-2-methoxy-4-methylpyridine also interacts with ATPase, which may lead to increased levels of ATP production, and has been shown to have antitumor effects in vitro.</p>

<p>Please enquire for more information about (Nle 35)-Amyloid b-Protein (1-40) ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>4-Aminobutyrophenone is a butyrophenone, a nitro compound that is the amine derivative of 4-aminobutyric acid. This product is used as a control agent in pest control and as an intermediate for pharmaceuticals and dyes. It has been used to produce methemoglobin, which is used to treat nitrate poisoning. 4-Aminobutyrophenone undergoes acylation reactions with chloride or sulfoxide groups to form chlorohydrins and thiohydrins respectively. These products are bioisosteres of the carbonyl group, which can be hydrolyzed with acid or alkali to produce carboxylic acids or alcohols respectively. Friedel-Crafts acylation with phenol gives benzoylphenylhydroxylamine, which can be oxidized by hydrogen peroxide to give the corresponding nitro compound.</p>

<p>Desmethyl sibutramine hydrochloride salt is a pharmaceutical preparation that has been used in the treatment of depression and chronic pain. It is a synthetic drug that increases the level of dopamine in the brain by inhibiting its reuptake. In addition, it has been shown to be effective in the treatment of hyperactivity, diabetic neuropathy, and other amines. Desmethyl sibutramine hydrochloride salt also has an antidepressant effect by decreasing serotonin reuptake.</p>

<p>Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 is a peptide hormone that is involved in the regulation of water balance and blood pressure. It is a vasoconstrictor and has been shown to have an inhibitory effect on cellular targets such as soluble guanylate cyclase, which are involved in the synthesis of cGMP. Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys Pro D Arg Gly NH2 also binds to the oxytocin receptor, which may be responsible for its vasodilatory effect.</p>

<p>Tetrabutylammonium nitrite is a tosylate salt. It reversibly binds to copper ions, forming a copper complex that is activated by the presence of nitroalkanes. The binding of tetrabutylammonium nitrite to glycosidic bonds in sugar residues, such as the hemoglobin molecule, leads to the formation of reactive oxygen species (ROS), which are responsible for cell damage. Tetrabutylammonium nitrite has been shown to reduce infarct size and improve cardiac function in animal models following ischemic reperfusion injury. Tetrabutylammonium nitrite also has antioxidant properties due to its ability to scavenge ROS and protect against oxidative stress.</p>

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<p>4-Methylaminophenol sulfate is an enzyme substrate that is used in the analytical method for determining the concentration of potassium dichromate. It is prepared by reacting 4-methylaminophenol with sulfuric acid, and its optimum concentration is 0.2 mM. The linear calibration curve was obtained at a pH range of 2 to 5.4 and a temperature range of 25 to 37°C. The analytical method can be applied to human serum samples and has been shown to be applicable for studies on autoimmune diseases and anthelmintics.</p>

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<p>Undecafluorohexanoic acid is a perfluoroalkyl carboxylic acid that has been shown to disrupt steroidogenesis in vitro. It may be able to inhibit the transport of cholesterol, fats, and other lipids in cells, which causes disruption in steroidogenesis. This compound also has anti-cancer properties due to its ability to induce apoptosis and arrest cancer cell proliferation. Undecafluorohexanoic acid may also have developmental effects on animals because it can bind to estrogen receptors and disrupt the normal process of estrogen-mediated signaling pathways.</p>

<p>Tetrapropylammonium perruthenate is a polymeric matrix that contains a chelate ligand and can be used as an oxygen sensor. The polymer is synthesized in the presence of trifluoroacetic acid (TFA) using tetrapropylammonium chloride (TPACl) and perruthenate. Tetrapropylammonium perruthenate forms a polymeric matrix with TPACl, which contains a chelate ligand. The polymer is sensitive to changes in the environment such as pH, temperature, and oxidation-reduction potential. The polymeric matrix can be used for sensing the concentration of oxygen in liquid or gas phase by measuring fluorescence intensity at various wavelengths. These measurements are correlated with the concentration of oxygen in the environment.</p>

<p>TES, also known as N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid, is a buffering agent that is used in protein assays and forms complexes with DNA and copper ions. The optimal pH range of this zwitterionic buffer is 6.8-8.2 and its pKa is 7.4.</p>

<p>6-Amino-4-(4-phenoxyphenylethylamino)quinazoline is a potential anticancer drug that has been shown to inhibit the polymerase chain reaction in human osteosarcoma cells. It also inhibits the signaling pathway of nuclear factor-κB (NF-κB), which is involved in cell death and tumorigenesis. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has shown significant cytotoxicity against murine hepatoma cells and bowel disease cells, but not against normal tissue. This drug is also an inhibitor of the drug transporter Pgp. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has been shown to be effective in experimental models for cancer, AIDS, and other infectious diseases.</p>

<p>Propylamine is a colorless, volatile liquid with a boiling point of -26.3°C. It has been shown to have the ability to react with sephadex g-100, which is a chromatographic material that separates proteins according to their size and charge. Propylamine has also been shown to undergo transfer reactions in the presence of hydroxyl groups and disulfide bonds. The chemical properties of propylamine have been studied using analytical methods such as nuclear DNA analysis, as well as biological studies involving the use of trifluoroacetic acid and nitrogen atoms for hydrogen bonding interactions.</p>

<p>Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.</p>

<p>Dextroamphetamine saccharate is a pharmaceutical drug that belongs to the group of amphetamine derivatives. It is used in the treatment of conditions such as narcolepsy and attention-deficit disorder (ADD). The epidermal growth factor receptor (EGFR) is an important target for the effects of this drug, which has been shown to stimulate growth and proliferation in vitro. Dextroamphetamine saccharate has a complex pharmacokinetic profile and is metabolized by hydrolysis into dextroamphetamine. This drug also binds to voltage-dependent calcium channels, which regulate neurotransmitter release at nerve terminals. The pain relief associated with dextroamphetamine saccharate may be due to its ability to block pro-inflammatory cytokines or inhibit trigeminal nerve activity.</p>

<p>Boc-4-aminopiperidine is a molecule that is used as a substrate in chemical reactions. It reacts with sodium hydroxide solution to form an imine, which is hydrogenated by reducing agents such as NaBH4. This reaction yields the products 4-aminopiperidine and acetaldehyde. Boc-4-aminopiperidine is also utilized as a cholinesterase inhibitor, which inhibits the breakdown of acetylcholine at nerve endings. The inhibitory activity of Boc-4-aminopiperidine can be determined using diagnostic techniques and it can be used to inhibit viruses such as HIV and influenza A virus.</p>

<p>EDTA ferric ammonium is a metal complex that is used in the manufacture of textile dyes. EDTA ferric ammonium is an oxidizing agent that can be used as a reducing agent by adding an oxidizing agent such as potassium permanganate. The solution form of this compound has a particle size distribution with a median particle size of about 0.5 micrometers and a polydispersity index of about 2. In addition, it has been shown to have surfactant properties, which may be due to its ability to interact with the surface tension of water molecules. EDTA ferric ammonium has also been shown to react with silver ions to form silver ethylene diamine tetraacetic acid (AgEDTA), which can then be used for patterning purposes in textiles.</p>

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<p>4-Aminopyrene is an aromatic amine that contains a nitro group. It has been used in biological studies to study the metabolism of amines, and chromatographic and mass spectrometric detection methods have been developed for its determination. 4-Aminopyrene also has the ability to form isomers through substitution on the N atom. The activation energy for this process is 14.3 kcal/mol. 4-Aminopyrene has been shown to be cytotoxic and mutagenic in vitro, and it can inhibit protein synthesis in bacteria by inhibiting RNA synthesis at the ribosome level. It has also been shown to induce changes in cell morphology and stimulate morphological differentiation of human promyelocytic leukemia cells (HL-60).</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>2-(4-Morpholinophenyl)ethylamine is a fine chemical that is a versatile building block, useful intermediate, and research chemical. It is used in the synthesis of complex compounds, useful building blocks, and high quality reagents. The CAS registry number for 2-(4-morpholinophenyl)ethylamine is 930779-56-9.</p>

<p>Please enquire for more information about 3-[2-Amino-3-(2-tert-butoxycarbonyl-ethoxy)-2-(2-tert-butoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R)(−)-DOI hydrochloride is a synthetic compound classified as a selective serotonin receptor agonist. It is primarily sourced from chemical synthesis processes designed to explore potential interactions within serotonergic pathways. The compound’s mode of action involves the activation of 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors, which play crucial roles in modulating neurotransmission and signaling pathways within the central nervous system.In research and experimental contexts, (R)(−)-DOI hydrochloride is utilized to investigate the molecular mechanisms of serotonin receptors, contributing to a deeper understanding of their role in neurophysiology and potential implications in neuropsychiatric disorders. Studies often explore its effects on cognition, perception, and mood regulation. Despite its promising role in scientific exploration, (R)(−)-DOI hydrochloride is not intended for therapeutic use and remains predominantly a tool for advancing the field of neuropharmacology through controlled experimental settings.</p>

<p>Please enquire for more information about 2-[(Ethylamino)methyl]-4-aminophenol dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Acetyl-6-(perfluoropropan-2-yl)-3-((pyridin-3-ylmethyl)amino)-3,4-dihydroquinazolin-2(1H)-one (PAFQ) is a mitochondrial cytochrome P450 inhibitor that inhibits the function of the ryanodine receptor and interacts with the piperonyl butoxide synergistically. PAFQ has been shown to be effective against animal pests such as termites, ants, and cockroaches. It also inhibits population growth in these populations by interfering with their ability to synthesize proteins. The effective dose for PAFQ varies depending on whether it is applied topically or orally.</p>

<p>8-Fluoro-Quinazoline-2,4-Diamine is an organic compound with the formula CHClN. It is a yellow solid that is soluble in organic solvents such as chloroform and toluene. The compound is used to produce dyes and pharmaceuticals. 8-Fluoro-Quinazoline-2,4-Diamine can be obtained by nitrating 2,4-diaminoquinazoline with nitric acid and hydrochloric acid in the presence of carbonate or stannous chloride. This reaction produces two isomers: 8-fluoroquinazoline (8FQ) and 6-fluoroquinazoline (6FQ). The 8FQ isomer has been shown to have a nuclear magnetic resonance spectrum at 300 MHz that contains four signals at 1.3 ppm, 3.5 ppm, 5.6 ppm, and 7.0 ppm, which are assigned to</p>

<p>2-[(2,3-Dimethylphenyl)amino]nicotinic acid is an arylpropionic acid that has been designed for the treatment of cancer. It is a neutral compound that can be crystallized or sterilized and then injected or implanted into tissues. The compound can be used as a diagnostic tool to target specific tissues in the body by using iontophoresis or organic solvents. 2-[(2,3-Dimethylphenyl)amino]nicotinic acid interacts with chlorine ions to form a chloride derivative, which is then transported through the tissue. This process can be reversed by adding an acid solution to the tissue, which will cause the chloride ions to break down into hydrogen and chloride ions.</p>

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<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

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<p>7-[(2S,3R)-3-Amino-2-methyl-azetidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-quinoline-3-carboxylic acid (ABT) is a drug that binds to bacterial enzymes and inhibits their ability to synthesize proteins. ABT is a conjugate of fluoroquinolone and an amino acid. As the drug is degradable by hydrolysis, it has been shown to be less toxic in Sprague Dawley rats than other fluoroquinolones. This drug has been used in diagnostic tests as a ligand for affinity ligands, but has not been approved for human use. The drug also possesses functional groups that are important for binding to reconstituted enzymes.br&gt;br&gt;ABT's ester linkages are degradable by hydrolysis and can be</p>

<p>[[4-[[2-(4-Cyclohexylphenoxy)ethyl]ethylamino]-2-methylphenyl]methylene]malononitrile (CAS #: 68436-91-7) is a reactive chemical species that has been used as a crosslinking agent and an uv absorption dye. CEM is a styryl dye that absorbs radiation in the uv range, with a maximum absorption at about 275 nm. It is a substrate film for light emission and can be used to measure viscosity. CEM is also chemically related to aromatic hydrocarbons and fatty acids, and can be synthesized from hydroxyl groups.</p>

<p>Benzydamine N-oxide is a polymorphic, michaelis-menten kinetics and pharmacological treatments drug. It has been shown to have anti-inflammatory effects in humans and animals. The main pharmacological targets of benzydamine are the human liver and alveolar type II cells. This drug has low bioavailability but is metabolized by the liver cells into benzydamine n-oxide which can be excreted through urine or bile. The formation rate of benzydamine n-oxide in the human body is about 2% per hour, which is dependent on the enzyme catalysis.</p>

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<p>Aminogenistein is a molecule that has been shown to inhibit the growth of cancer cells. It has been shown to have a reactive functional group, which can be used as a diagnostic and prognostic tool for kidney disease and cancers. Aminogenistein has also been shown to inhibit epidermal growth factor (EGF) in rat kidneys, which may be due to its ability to bind EGF with high affinity. In addition, it has been shown to inhibit cellular physiology by blocking the transport properties of proximal tubules in rat kidneys. Aminogenistein is thought to induce apoptosis through the death protein pathway in cancer cells, but not normal cells.</p>

<p>(+)(1S,2S,4R)-Bicyclo[2.2.1]heptane-2-amine is a heterocyclic compound that contains a nitrogen atom and an amine group. It has been shown to be a potent inhibitor of the enzyme activities of malonic acid decarboxylase and acetylcholinesterase. This compound can be used as a diagnostic tool for chronic kidney disease, specifically in cases of renal failure and polycystic kidney disease. The palladium complexes can be used for the synthesis of (+)(1S,2S,4R)-bicyclo[2.2.1]heptane-2-amine in high yield from malonic acid and ammonia.</p>

<p>2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline (2HAIQ) is a reactive compound that binds to DNA. It has been shown to be a potent inhibitor of the enzyme cytosolic protein kinase C, which plays an important role in regulating cellular metabolism. 2HAIQ also inhibits the activity of enzymes such as hydroxylases and polymerases. The binding of 2HAIQ to DNA is thought to inhibit transcription by preventing RNA polymerase from transcribing DNA. 2HAIQ may also inhibit replication by binding to the dinucleotide phosphate molecule, which is essential for DNA synthesis.</p>