Cyano-, Nitrile-

<p>Stability Light Sensitive, Moisture Sensitive<br>Applications (S)-2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile is used as a reagent in the synthesis of Fluvalinate (F601100) and its related analogs which exhibit insecticidal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, R.J., et al.: J. Agr. Food Chem., 33, 508 (1985)<br></p>

<p>Applications Isocyanobenzene is used in the study of the inhibition mechanism of reconstituted cytochrome p-450scc-linked monooxygenase system by antimycotic reagent and other inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kurokohchi K., et al.: J. Steroid Biochem. Mol. Biol., 42, 287 (1992)<br></p>

<p>Stability Light Sensitive<br>Applications Dibromoacetonitrile is a carcinogenic nitrogenous disinfection byproduct. Dibromoacetonitrile in drinking water was linked to oral cavity cancer in rats and forestomach cancer in mice. In addition, Dibromoacetonitrile may cause oxidative damage in rat brain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, Z., et al.: Chem. Eng. J. 306, 1180 (2016); Krasner, S. W., et al.: Environ. Sci. Technol. 50, 9583 (2016); Natl Toxicol Program Tech Rep Ser. 544, 1 (2010); Klattisaksiri, P., et al.: Water Res 98, 160 (2016); Sayed, R. H., et al.: Environ Toxicol Pharmacol. 34, 849 (2012)<br></p>

<p>Applications 1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists.<br>References Sarges, R. et al.: J. Med. Chem., 31, 230 (1988); Mann, A. et al.: J. Med. Chem., 34, 1307 (1991);<br></p>

<p>Applications Reagent used in labelled pyrimidine and purine synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Das, S., et al.: J. Med. Chem., 52, 5937 (2009), Kim, K., et al.: Bioorg. Med. Chem. Lett., 19, 5225 (2009),<br></p>