Cétones

<p>SNB1750 - bis(2,4-Pentanedionato)dichlorotin</p>

<p>Applications Methyl Pentadecafluoroheptyl Ketone 754-85-8 (cas# 754-85-8) is a useful research chemical.<br></p>

<p>Applications Reagent used in the preparation of carbazole derivatives<br>References Dong, Y., et al.: J. Med. Chem., 48, 4953 (2005),<br></p>

<p>Applications 8-Didemethyl Baquiloprim-2,4-dione is an intermediate used in the synthesis of Baquiloprim (B118000), which is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim.<br>References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)<br></p>

<p>Applications 1,4-Cyclohexanedione Monoethylene Acetal is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.<br>References Linders, J. et al.: J. Lab. Comp. Radiopharm., 31, 671 (1992); Lednicer, D. et al.: J. Med. Chem., 22, 1157 (1979);<br></p>

<p>Applications Intermediate in the synthesis of protein kinase inhibitors<br>References Pruehs, C., et al.: Bioorg. Med. Chem. Lett., 17, 1850 (2007), Stukenbrock, H., et al.: J. Med. Chem., 51, 2196 (2008),<br></p>

<p>Applications Diphenyl-methanone Hydrazone is an intermediate used to synthesize Pseudobenztropine (P840155), an analog of Benzotropine (B207575, Mesylate salt) which is used as an antiparkinsonian.. It can also be used to prepare chiral [2.2]paracyclophane-substituted triazolium salts as precursors for copper-triazolylidene-catalyzed asymmetrical boration of unsaturated N-acyloxazolidinones.<br>References Hai, N., et al.: Int. J. Pharm., 357, 55 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009); Zhan, M., et al.: Org. Lett., 15, 4182 (2013)<br></p>

<p>Applications Hexachloropropanone is a useful synthetic intermediate. It is a reagent used for the conversion of nucleoside-3′-phosphonates to the corresponding phosphates and for the polymerization of vinyl compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Garegg, P., et al.: J. Chem. Soc. Perkin Trans. I, 6, 1269 (1972); Deming, T., et al.: 26, 7089 (1993)<br></p>

<p>Applications 3,3,5,5-Tetramethylcyclohexanone (cas# 14376-79-5) is a useful research chemical and a pharmaceutical intermediate.<br>References Ebrahimi, H. P., et al.: Spectrochim. Acta A: Mol. Biomol. Spectrosc., 137, 1067 (2015); Bishop, A. C., et al.: Bioorg. Med. Chem. Lett., 16, 4002 (2006)<br></p>

<p>Applications 2-(Dimethylaminomethylene)cyclohexanone is an intermediate in the synthesis of 2-Pentylidenecyclohexanone (P280255), a fragrance chemical. It can also be used in the synthesis of dialkylphenols in the presence of zirconium catalyst.<br>References Tetsuo, B. et al.: Kenkyu Hokoku - Asahi Garasu Zaidan, 58, 201 (1991); Hostynek, J. J., et al.: Toxicology in Vitro, 11, 377 (1997);<br></p>

<p>Applications 3-(Dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.<br>References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);<br></p>

<p>Applications 1-(3,4-Dimethoxyphenyl)-2-butanone (cas# 884-06-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Benzyl 4-Fluorophenyl Ketone is used in the preparation and evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors.<br>References Singh, S. et al.: Bioorg. Med. Chem., 12, 1881 (2004);<br></p>

<p>Applications 5-Bromo-1-(2-fluorophenyl)-2-pentanone is an intermediate in the synthesis of Prasugrel (P701150). Prasugrel is a novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome.<br>References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),<br></p>

<p>Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications 1-(4-Benzylphenyl)ethanone is used in the preparation of di- and triarylmethanes through palladium-catalyzed reductive coupling of N-tosylhydrazones and aryl bromides.<br>References Xia, Y., et al.: Synthesis., 49, 1073-1086 (2017)<br></p>

<p>Applications 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>

<p>Covid-19 is a synthetic compound that has been shown to have antiviral activity. Covid-19 is a carotenoid derivative that is hydrophobic and does not dissolve in water. It is oxidized to produce an isomeric mixture of products, which are characterized by vibrational spectroscopy. Covid-19 has synergistic effects with ethyl bromoacetate, which is a solvent with low energy. Covid-19 can be extracted from the sample using solid phase microextraction (SPME).</p>

<p>2-Indanone is a molecule with the chemical formula C6H2O. It belongs to the class of methyl ketones and has the chemical structure as shown on the right. 2-Indanone can be synthesized by coupling a sodium carbonate and an analog of curcumin. A covid-19 pandemic amination reaction is used to produce this compound. The synthesis starts with a zirconium dichloride and triethyl orthoformate, which are then oxidized to form naphthalene and carbonyl group, respectively. The enolate group is then formed by adding an alkoxide ion or base to the ketone.</p>

<p>Boc-(3S)-3-amino-4-phenyl-2-butanone is a chemical intermediate that is useful as a building block in organic synthesis. It has been used as a reaction component, reagent and high quality research chemical. Boc-(3S)-3-amino-4-phenyl-2-butanone is also a versatile building block and useful intermediate for the preparation of complex compounds. This chemical has shown to have speciality applications in fine chemicals such as pharmaceuticals and agrochemicals.</p>

2-Chlorophenylacetone is an organic chemical compound that is a substrate for enzymes. It can be used as a reagent in the synthesis of phenylacetone and other substituted phenylacetic acids, which are chiral starting materials used in the production of pharmaceuticals, pesticides, dyes, and plastics. 2-Chlorophenylacetone binds to the active site on enzymes that catalyze reactions involving ethylene, nitroethane, chloride and phenylacetone. The binding site is defined by amino acid residues at positions corresponding to glycine (G), alanine (A), and aspartic acid (D) in the enzyme's active site. 2-Chlorophenylacetone has been shown to be a powerful inhibitor of dehydrogenase activity with IC50 values of 1.5 mM for acetaldehyde dehydrogenase from yeast cells and 3.2 mM for alcohol dehydrogenase from rat liver mitochondria. In addition, it

<p>Iprodione is an ester hydrochloride that belongs to the class of fungicides. It has been shown to have high resistance and is used in vitro assays to detect mutants with a high degree of resistance. Iprodione inhibits the growth of wild-type strains, but not resistant mutants, by inhibiting protein synthesis at the ribosome level, blocking the polymerase chain reaction and DNA replication. This prevents transcription and replication of genetic material. Iprodione also inhibits nitrite ion production in wild-type strains and has genotoxic effects on cultured human cells. The drug is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>5-Ethoxy-2(5H)-furanone is an oxidation product of 5-ethoxy-2(5H)-furanone. It has an isomeric, stereospecific, regiospecifically, and a tautomeric relationship with furfural. 5-Ethoxy-2(5H)-furanone can be produced by the oxidation of furfural with boron trifluoride etherate in the presence of iodosobenzene. The reaction mechanism involves the addition of hydrogen peroxide to the boron trifluoride etherate to form hydroperoxydiborane. This compound then reacts with iodosobenzene to produce 5-ethoxy-2(5H)-furanone and 2,5-dihydroxybenzaldehyde. The reaction produces a mixture of diastereomers that contain different numbers of carbon atoms due to the regiospecific</p>

<p>2,4-Dien-1-one is a cyclic dienone that is used in the preparation of various pharmaceutical drugs. It has been reported to be an excellent building block for the synthesis of complex compounds. This compound has shown antimicrobial activity against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis.<br>2,4-Dien-1-one is a versatile intermediate that can be used as a speciality chemical or research chemicals. It is also a useful scaffold for the synthesis of various pharmaceutical drugs and can be used as a reaction component for various reactions.</p>

<p>Cyclohexylacetone is a colorless liquid that is used as a solvent for the production of pharmaceutical preparations. It has been used to produce methyl ketones, which are intermediates in the synthesis of polymers and plastics. Cyclohexylacetone has also been shown to be an optimal reaction intermediate for the preparation of zirconium oxide. This compound is used as a polymerization initiator and as a fluorine-containing reagent in organic synthesis. Cyclohexylacetone can react with divalent hydrocarbons to form esters and cyclooctyl compounds.</p>

<p>3-Ethoxy-4-hydroxyphenylacetone is a fine chemical that can be used as a versatile building block and useful intermediate. It has a CAS number of 88659-82-9. 3-Ethoxy-4-hydroxyphenylacetone is a complex compound with many uses, such as research chemicals, reaction component, or speciality chemical. It is water soluble and has been shown to be non toxic. The purity of the product is high quality.</p>

<p>Diacetone acrylamide is a chemical compound that has the molecular formula C3H6O2N2. It is a colorless liquid with a low boiling point and an unpleasant odor. Diacetone acrylamide has been used as an intermediate in the production of polyvinyl acetate. It can also be used as an additive to rubber, plastics, and other materials. The thermal expansion coefficient of diacetone acrylamide is similar to that of polyvinyl chloride and polystyrene, making it a useful material for constructing models of those substances.</p>

1-Benzofuran-2-yl(phenyl)methanone (1BFPM) is a benzofuran derivative. It has been shown to have significant cytotoxicity and anticancer activity, as well as radical scavenging activities. 1BFPM has been shown to inhibit glycogen synthase kinase-3, which is an enzyme that regulates the cell cycle and plays a role in tumorigenesis. This compound also inhibits the uptake of 1BFPM by cells, which may be due to its reaction with linkers in the plasma membrane or other cellular membranes.

<p>2-Undecanone is a fatty acid that has been isolated from the leaves of Melaleuca alternifolia. It has been shown to have anti-inflammatory and antifungal properties and can inhibit the production of cytokines, such as tumor necrosis factor (TNF) and interleukin (IL)-1β. 2-Undecanone also inhibits the Toll-like receptor 4 signaling pathway. This compound is an effective inhibitor of fungal growth in vitro, with activity against Candida albicans, Saccharomyces cerevisiae, Cryptococcus neoformans, Aspergillus niger, Penicillium chrysogenum, and other fungi. The analytical method for 2-undecanone includes gas chromatography/mass spectrometry using a capillary column and electron impact ionization with chemical ionization at 70 eV.</p>

<p>1-(3-Chlorophenyl)-2-hydroxy-1-propanone is an optically active intermediate that is used in the synthesis of pharmaceuticals. It has been shown to be an enantioselective transesterification agent, and can be used in the preparation of esters such as hexane, butanoate and vinyl. The substrate concentration affects the yield of this compound, which may be due to its chiral nature. 1-(3-Chlorophenyl)-2-hydroxy-1-propanone is soluble in organic solvents such as hexane, dichloromethane, benzene and acetone.</p>

<p>5alpha-Pregnane-3,20-dione is a naturally occurring sex steroid hormone. It is produced by the ovaries and testes in humans and other mammals, as well as by the adrenal glands in small amounts. 5alpha-Pregnane-3,20-dione has been shown to inhibit the enzyme activity of hepatic microsomes that are responsible for the conversion of progesterone to 17beta-hydroxyprogesterone (17betaOHP). This inhibition is due to its ability to bind to glucocorticoid receptors. 5alpha-Pregnane-3,20-dione also inhibits fatty acid synthesis in liver cells. The drug's antiproliferative effects on ovarian cells are mediated through a number of mechanisms including transcriptional repression of progesterone receptors and estradiol benzoate binding sites on DNA. 5alpha-Pregnane-3,20-dione has been shown to have an optimal</p>

(3-Bromo-4,5-dimethoxyphenyl)acetone is a reagent that is used as an intermediate in the synthesis of a variety of compounds. It also has potential use as a building block for the synthesis of a wide range of complex compounds. (3-Bromo-4,5-dimethoxyphenyl)acetone can be used as a building block for chemical reactions and research chemicals. This compound has been shown to have versatile applications and is useful in the synthesis of fine chemicals, speciality chemicals, and research chemicals.

<p>(3,4-Dimethoxy-5-hydroxyphenyl)acetone is a fine chemical that belongs to the class of compounds known as reagents. It has been used in research and development as a building block or intermediate for the synthesis of other chemicals. It is also used as a versatile building block in complex organic syntheses, such as pharmaceuticals. The chemical is soluble in organic solvents and reacts with many other chemicals, making it useful for synthetic chemistry. This compound has been shown to be high quality and can be used to synthesize other chemicals with diverse properties.</p>

<p>4-Aminopyridazin-3(2H)-one is an antiplatelet drug that has been shown to have a pharmacological effect on the central nervous system. It is also used as a chemotherapeutic agent for the treatment of certain types of cancer. 4-Aminopyridazin-3(2H)-one contains two nitrogen atoms that are substituted with methyl groups, which can be hydrolyzed by liver enzymes to form pyridazine and 4-aminopyridine. 4-Aminopyridazin-3(2H)-one inhibits bacterial growth by inhibiting protein synthesis and cell division at the ribosome level. This drug also has antimicrobial activity against Gram-positive bacteria and fungi, but is not active against Gram-negative bacteria such as Escherichia coli.</p>

<p>This is a quinoline derivative that has been shown to have inotropic and cardioprotective effects. It has been shown to increase the duration of action potentials and contractions in isolated heart muscle, as well as to improve the function of the heart by reducing the rate of myocardial oxygen consumption. 6-Hydroxy-3,4-dihydro-1H-quinoline-2-one has been shown to have anti-inflammatory properties and may be useful for treating respiratory diseases such as asthma. This compound is also used as a precursor for some pharmaceutical drugs, including chloroquine, mefloquine, amodiaquine, and primaquine. The compound is metabolized into conjugates that are recycled back into the body or excreted in human urine; this process is regulated by the balance between conjugation reactions and hydrolysis reactions.</p>

Tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct is a catalyst that is used in cross-coupling reactions. It is an efficient method for the preparation of β-unsaturated ketones, which are important intermediates in organic synthesis. The catalytic cycle involves hydrolysis and condensation reactions. Tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct can be prepared by reacting chloroform with a palladium compound in the presence of silver trifluoromethanesulfonate and a diphosphine ligand. The product contains a chloroform molecule that can be replaced by other functional groups such as chloride, fatty acid, or imine nitrogen. Tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct has been characterized by x-ray crystal structures to identify

<p>1,5-Bis(4-Methyl-naphthalene-1-yl)-pentane-1,5-dione is a high quality chemical that is used as an intermediate in the production of various complex compounds. It has been shown to be a useful scaffold for the synthesis of novel compounds with a variety of properties and uses. This compound can be used as a building block in reactions to produce speciality chemicals, research chemicals, and versatile building blocks. 1,5-Bis(4-Methyl-naphthalene-1-yl)-pentane-1,5-dione is also a reaction component that is used in the synthesis of various other compounds.</p>

<p>Dantrolene is an experimental model for malignant hyperthermia, a rare genetic condition that can cause muscle rigidity and death. Dantrolene has been shown to inhibit the activity of the dinucleotide phosphate (NADH) dehydrogenase enzyme in muscle cells. In addition, it inhibits calcium release from the sarcoplasmic reticulum and activates ryanodine receptors. Dantrolene also inhibits muscle contractions and prevents neuronal death by inhibiting the release of glutamate.</p>

<p>1-(4-Bromophenyl)propan-1-one is a sulfonation product of propiophenone. It has been found to have anticancer activity in cervical cancer, and is currently being studied as a potential treatment for cancer. 1-(4-Bromophenyl)propan-1-one can be synthesized by treating propiophenone with hydrochloric acid and sodium hydroxide solution. It can also be synthesized using polyvinyl chloride as the starting material. 1-(4-Bromophenyl)propan-1-one can be isolated from the reaction mixture by adding hydrochloric acid to the reaction mixture, forming a salt that precipitates from solution. This salt is then dissolved in water and neutralized with an alkali such as sodium hydroxide or potassium carbonate, yielding 1-(4-bromophenyl)propan-1-one hydrochloride.</p>

<p>1-Phenyl-3-aminopyrazol-5-one is a solvent that can be used in elemental analysis. It has a molecular weight of 137.12 and is soluble in water, methanol, ethanol, acetone, ether, benzene and chloroform. 1-Phenyl-3-aminopyrazol-5-one has been shown to react with amines and form tautomers with different chemical properties. The spectral data for this compound are presented as the absorption spectra of substituted 1-phenyl-3-aminopyrazol-5-ones with acetyl groups at C2 and C4 (1), the nuclear magnetic resonance spectrum of 1-(dimethylamino)ethyl 3-[2-(N,N'-dimethylamino)ethyl]pyrazole (2), the NMR spectrum of 2-(dimethylamino)ethyl 3-[2-(N,N'-dimethylamino)ethyl]</p>

<p>(2-Hydroxy-5-methoxyphenyl)acetone is a fine chemical that belongs to the group of complex compounds. It can be used as an intermediate for research chemicals, as well as a useful scaffold or building block. This compound can be converted into other useful compounds through reactions with alcohols, amines, or ketones. (2-Hydroxy-5-methoxyphenyl)acetone is also used in the synthesis of speciality chemicals and reaction components for pharmaceuticals.</p>

<p>3-Ethyl-4-methyl-3-pyrrolin-2-one is a sulfonated dione that can be synthesized from chloroformates. The product yields are high and the compound is stable to heat, light, and hydrolysis. The compound crystallizes in a single pure form and does not contain any impurities. 3-Ethyl-4-methyl-3-pyrrolin-2-one has been used as a precursor for the synthesis of various other organic compounds. It can also be used to synthesize dimers with an aryl group at the end of the molecule.</p>