Cétones

<p>Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.<br></p>

<p>Applications 5-[(4-Fluorobenzylidene]-2,4-thiazolidinedione (cas# 262601-87-6) is a compound useful in organic synthesis.<br></p>

<p>Applications (E)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.<br>References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)<br></p>

<p>Applications 1-​(3-​Hydroxyphenyl)​-​1-​propanone is a reactant used to synthesize tricyclic fused pyridines, a family of alkaloids with antimalarial activity.<br>References Zheng, L., et al.: J. Org. Chem., 81, 8911-8919 (2016)<br></p>

<p>Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).<br>References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);<br></p>

<p>Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.<br>References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);<br></p>

<p>Applications (2E)-2-Hexylidenecyclopentanone, is a compound that is found in fragrance.<br>References Scognamiglio, J., et al.: Food Chem. Tox., 3, S577 (2012)<br></p>

<p>Applications 4-Hydroxyphenylacetone (cas# 770-39-8) is a useful research chemical.<br></p>

<p>Applications (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.<br>References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981); Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987)<br></p>

<p>Applications 1-(2,5-Dihydroxyphenyl)ethanone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.<br>References Zhao, W., et al.: Bioorg. Med. Chem., 19, 3192 (2011); Jayashree, B.S., et al.: Asian. J. Chem., 22, 1055 (2010); Benites, J., et al.: Bioorg. Med. Chem., 16, 862 (2008);<br></p>

<p>Applications 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE (cas# 2892-51-5) is a useful research chemical.<br></p>

<p>Applications 1-(2-AMINO-5-HYDROXYPHENYL)ETHANONE (cas# 30954-71-3) is a useful research chemical.<br></p>

<p>Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.<br>References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)<br></p>

<p>Applications Cyclododecanone is a general chemical reagent used in organic synthesis.<br>References Hu, Y. et al.: Org. Biomol. Chem., 14, 3022 (2016);<br></p>

<p>Applications 1-Cyclohexylethanone is used in the synthesis of thiosemicarbazide derivatives which exhibits biological activity.<br>References Venkatesh, K., et al.: J. Chem. Pharm. Res., 7, 437-445 (2015)<br></p>

<p>Please enquire for more information about 1-Benzyl-4-methylpiperidin-3-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 17-Oxapentacyclo[6.6.5.0-2,7-.0-9,14-.0-15,19-]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 17-Hydroxy-19-nor-17alpha-pregna-4,6-dien-20-yn-3-one acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(Hydroxymethyl)pyrrolidin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Aminothiophen-3-yl)(4-bromophenyl)methanone is a new compound that is being developed as a potential antiviral agent. Covid-19, the trade name for 2-aminothiophen-3-yl)(4-bromophenyl)methanone, prevents the replication of viruses by binding to their nucleic acids and blocking their ability to produce proteins. Covid-19 has been shown to be effective against both influenza A and B viruses in cellular and animal models. The antiviral activity of Covid-19 is due to its ability to bind to viral nucleic acid, preventing the production of proteins vital for viral replication. This compound has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of amyloid plaques in mice with Alzheimer's disease.</p>

<p>1-Methyl-1,3-dihydro-2H-imidazol-2-one is a chemical compound with the formula CHN. It has been used as a precursor to other compounds and can be prepared by reaction of methanol with chlorine or chloramine. 1,3-Dihydroimidazole reacts with UV light to generate photoproducts that contain pyrimidine or pyridinium rings. It is also reactive with chloride ion and can be used as a raw material for organic synthesis. 1,3-Dihydroimidazole can also be synthesized from chlorinated methanesulfonate esters.</p>

Please enquire for more information about 9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>3-Amino-2-methylquinazolin-4(3H)-one is a bidentate ligand that has been shown to have antibacterial and anticancer activity. The functional theory of the compound is based on its ability to form an imine nitrogen with metal ions such as Fe(II) or Cu(II). 3-Amino-2-methylquinazolin-4(3H)-one is not active against Staphylococcus aureus, but inhibits the growth of other bacteria by binding to their ribosomes and inhibiting protein synthesis. 3-Amino-2-methylquinazolin-4(3H)-one also has in vitro anticancer activity, which may be due to its ability to inhibit DNA synthesis and cell division.</p>

<p>Tris(dibenzylideneacetone)dipalladium(0) (Pd2(dba)) is a monoclonal antibody that is used to treat infectious diseases. The metal complex binds to the fatty acid and inhibits the synthesis of membrane lipids, which leads to an inhibition of virus replication. Tris(dibenzylideneacetone)dipalladium(0) has been shown to have potent antitumor activity in animal models, with cytotoxic effects on mutant melanoma cells and hydrochloric acid. This drug also has potent pro-apoptotic properties, inducing apoptosis by binding to pro-apoptotic proteins. Tris(dibenzylideneacetone)dipalladium(0) has been shown to be a potent inhibitor of x-ray crystal structures at high temperatures, where it competes with water for the labile hydrogen atoms on the surface of hydroxyl groups.</p>

<p>Please enquire for more information about [4-[2-(Diethylamino)ethoxy]-3-iodophenyl][2-(1-hydroxybutyl)-3-benzofuranyl]-methanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Fmoc-4-(3-carboxymethyl-2-keto-one-benzimidazolyl)piperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 5-Chloro-2-hydroxy-2-methoxycarbonyl-1-indanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(4-Chloro-benzyl)-2H-phthalazin-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride is a racemic mixture of two enantiomers. It is a prodrug that is hydrolyzed to its active form, diltiazem. The drug has been shown to be effective in the treatment of hypertension and angina pectoris. (2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride has been shown to inhibit the activity of the enzyme phosphodiesterase which breaks down cyclic AMP. This inhibition results in an increase in levels of</p>

<p>1-Amino-2,4-imidazolidinedione-13C3 is an antibiotic that belongs to the group of nitrofurans. It is used for the treatment of infections caused by bacteria that are resistant to other antibiotics. The LC-MS/MS analysis showed that 1-aminohydantoin was formed as a degradation product of chloramphenicol and that this metabolite had been detected in urine samples from patients treated with chloramphenicol. Nitrofuran is also a possible degradation product. A reaction monitoring experiment using ionization monitoring and monitoring on the precursor ion at m/z 287 confirmed the presence of 1-aminohydantoin in a sample containing both chloramphenicol and nitrofuran. Quantification was performed using calibration curves obtained from pure standards.</p>

<p>The 1-benzhydrylazetidin-3-one molecule has an ionizing potential of 29.6 eV, which is the amount of energy required to remove one electron from the outermost shell of a hydrogen atom. The molecule is photoelectron reactive, with a reaction yield of 0.5%. It reacts with ultraviolet radiation and interacts with other molecules such as azetidine (2-methylaziridine). The 1-benzhydrylazetidin-3-one molecule has an ionization potential of 29.6 eV, which is the amount of energy required to remove one electron from the outermost shell of a hydrogen atom. The molecule is photoelectron reactive, with a reaction yield of 0.5%. It reacts with ultraviolet radiation and interacts with other molecules such as azetidine (2-methylaziridine).</p>

<p>Fidovirsen is a nucleoside analogue that is an inhibitor of the NS3 protease of hepatitis C virus (HCV). Fidovirsen binds to the active site of the NS3 protease and prevents cleavage at the NS3/4A interface, thus inhibiting viral replication. It has been shown to be effective in clinical studies involving human liver samples. Fidovirsen has also been shown to have antiviral activity against other RNA viruses, including HIV-1 and influenza A virus. Fidovirsen has a low toxicity profile and does not exhibit cross-resistance with other antiviral drugs. The drug is being developed as a potential therapy for chronic HCV infection.</p>

<p>Please enquire for more information about (1-Methyl-1H-imidazol-2-yl)(4-methylphenyl)methanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about 1-(1-Benzyl-1H-indol-3-yl)ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 3-Amino-6,7-dimethoxy-2-methylquinazolin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Amino-6-bromo-2-methylquinazolin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 6-Bromo-3-(4-chlorophenyl)quinazoline-2,4(1H,3H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about 3-(Dimethylamino)-1-(1-methyl-1H-indol-2-yl)prop-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Piperidine-2,5-dione is a synthetic compound that is used for the synthesis of benzyl esters, stereospecific chiral compounds, and amides. It can be used as a building block in the synthesis of natural products. Piperidine-2,5-dione has been shown to inhibit the activity of enzymes such as lactamases and amidases. The mechanism by which piperidine-2,5-dione inhibits these enzymes is not yet known. This compound also can react with potassium hydride to form radical species or alkylate boronic acids to form stereochemically pure products.</p>

<p>Please enquire for more information about 2-Methyl-6,7-dihydro-2H-indazol-4(5H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one is a cholinergic drug that is used as a research tool in vitro. It has been shown to increase the concentration of acetylcholine in the synapse. It is also known as cytisine and varenicline. 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one binds to nicotinic receptors and stimulates them. This increased activity of nicotinic receptors leads to the release of acetylcholine (ACh), which is an important neurotransmitter in the brain. 1,2,3,4 5 6 hexahydro - 1 5</p>