Amides

<p>Applications Pivalimidamide Hydrochloride is used as a reagent in the preparation of 2-alkyl-4-aryltetrahydropyridopyrimidines and 2-alkyl-4-aryl-tetrahydropyrimidoazepines as selective 5-HT2A antagonists.<br>References Shireman, B. T., et al.: Bioorg. Med. Chem. Lett., 18, 2103 (2008);<br></p>

<p>Applications N,N-Diisopropylformamide (cas# 2700-30-3) is a useful research chemical.<br></p>

<p>Applications N-(2-Hydroxyethyl)pentadecanamide could acts as an inhibitor of hydrogen sulfide corrosion of steel in the system petroleum-​electrolyte.<br>References Mamedov, I. A., et al.: Korroziya i Zashchita v Neftegazovoi Promyshlennosti, 11-14 (1971)<br></p>

<p>Applications N-Cyclopropyl 5-bromonicotinamide<br></p>

<p>Applications 3,8-Diimino-4,7-dimethyl-2,4,7,9-tetraazadecanediimidamide is a useful research chemical.<br></p>

<p>Applications N-Butyl-3-hydroxybenzamide<br></p>

<p>Applications tert-Butylsulfinamide can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. tert-Butylsulfinamide is also used as a reagent in the synthetic preparation of amide series as BACE1 inhibitor and potential anti-Alzheimer’s drug.<br>References Szallasi, A., et al.: Pharmacol. Rev., 51, 159 (1999), Montell, C., et al.: Mol. Cell., 9, 229 (2002), Ryu, C., et al.: Bioorg. Med. Chem. Lett., 14, 1751 (2004), Suh, Y., et al.: J. Med. Chem., 48, 5823 (2005); Woltering, T. J., et al.: Bioorg. Med. Chem. Lett., 23, 4239 (2013)<br></p>

<p>Applications N-(4-Hydroxymethylbenzyl)trifluoroacetamide (cas# 171723-95-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-{2-[(4-Hydroxyphenyl)sulfanyl]ethyl}acetamide (cas# 91281-32-2) is a useful compound for use as a skin-lightening agent; cosmetic applications.<br>References Parvez, S., et al.: Phytother. Res., 20, 921 (2006)<br></p>

<p>Applications 3,5-Di-tert-butyl-4-hydroxybenzamide is used in the preparation of 2-(3,5-di-tert-butyl-4-hydroxyphenyl)oxazoles as anti-atherosclerotic agents.<br>References Steinberg, et al.: Am. J. Cardiology, 57, 16 (1986), Reaven, et al.: Arteriosclerosis and Thrombosis, 12, 318 (1992),<br></p>

<p>Applications N-Dimethyl-(furan-3-ylmethyl)carbamothioyl)methanethioamide is an intermediate used in the synthesis of 3-((Furan-2-ylmethyl)imino]-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine Hydrobromide (F864125), which is an insect chemosterilant and an agrochemical.<br></p>

<p>Impurity Atenolol EP Impurity A<br>Applications 4-(Hydroxyphenyl)acetamide (Atenolol EP Impurity A) is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)<br>References Inkum, R., et al.: Maejo Int. J. Sci. Tech., 6, 372 (2012); Pai, N.R., et al.: J. Chem. Pharma. Rsch., 4, 375 (2012); Moon, J.T., et al.: Bio-org. Medn. Chem., 20, 734 (2012);<br></p>

<p>Applications 4-(2-Hydroxy-1,1-dimethylethyl)benzenesulfonamide (cas# 374067-96-6) is a compound useful in organic synthesis.<br>References Morimoto, H., et al.: J. Med. Chem., 44, 3369 (2001),<br></p>

<p>Applications 2,3-Dihydroxybenzamide is a disubstituted benzamide used in the preparation of a catechol metabolite of dilevalol. 2,3-Dihydroxybenzamide is also used in the preparation of iron chelating agents.<br>References Tulshian, D.D. et al.: Bioorg. Med. Chem. Lett., 3, 2073 (1993); White, G.P. et al.: Brit. J. Haematol., 33, 487 (1976);<br></p>

<p>Applications 2-Hydroxy-5-nitrobenzamide is used in the synthesis of salicylamides and its nitro derivatives.<br>References Gupta, G. L.: J. Proc. Inst. Chem., 38, 165 (1966)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-isothiocyanatoacetamide (cas# 145518-36-1) is a useful research chemical.<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Stability Not stable in Strong Base<br>Applications 3-Hydroxyisothiazole-5-carboxylate (cas# 62020-63-7) is a compound useful in organic synthesis.<br></p>

<p>Applications N,N-Diethyl-p-toluamide, is a buildig block used in the synthesis of phthalocyanines. It can also be used in preparation of new insect repellents.<br>References Liang, J., et al.: Nongyaoxue Xuebao, Vol. 16,P: 644-650 (2014);<br></p>

<p>Applications N-(2,4-dimethylphenyl)acetamide (cas# 2050-43-3) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of antifungal agents.<br>References Del Poeta, M. et al.; Antimicrob. Agents Ch., 42, 2495 (1998)<br></p>

<p>Applications Reproduction of Sindbis virus strains sensitive and resistant to 1-adamantanecarboxamide.<br>References Erice, A., et al.: N. Engl. J. Med., 320, 289 (1989), Andronova, V.L., et al.: Bull. Exper. Bio. Med., 129, 74 (2000).<br></p>

<p>Applications N-BENZYLBENZAMIDE (cas# 1485-70-7) is a useful research chemical.<br></p>

<p>Applications Methacrylamide (cas# 79-39-0) is a useful research chemical.<br></p>

<p>Applications N-Benzylpropanamide is an intermediate in the synthesis of N-Ethyl-N-nitroso-1-propanamine-d4 (E817997) and isotope labelled version of N-Ethyl-N-nitroso-1-propanamine. N-Ethyl-N-nitroso-1-propanamine is a derivative of N-Nitrosodiethylamine (N525465),a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.<br>References Shirakami, Y., et al.: Bitamin, 87, 156 (2013); Fujii, Y., et al.: Toxicol., 305, 30 (2013); Uehara, T., et al.: Toxicol. Sci., 132, 53 (2013);<br></p>

<p>Applications 5-Fluoronicotinamide<br></p>

<p>Applications 6-chloro-imidazo[2,1-b]thiazole-5-sulfonic acid amide (cas# 112582-89-5) is a useful research chemical.<br></p>

<p>Applications Intermediate in the preparation of nitro substituted quinazolones.<br>References Tobe, M., et al.: Bioorg. Med. Chem., 11, 3869 (2003), Chinigo, G., et al.: J. Med. Chem., 51, 4620 (2008),<br></p>

<p>Applications N-(2-(1,3-Dioxoisoindolin-2-yl)ethoxy)benzamide is an intermediate in the synthesis of Fluvoxamine Maleate (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.<br>References Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977); Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996); Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997); Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)<br></p>

<p>Applications N-(3,4-dimethylphenyl)acetamide (cas# 2198-54-1) is a useful research chemical.<br></p>

<p>Applications Tosyl Brinzolamide is a derivative of Brinzolamide (B677601) which is a carbonic anhydrase inhibitor and an antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998);Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000); Stave, J., et al.: Ophthalmologe, 99, 276 (2002);<br></p>

<p>Stability Moisture Sensitive<br>Applications N-Phenylbis(trifluoromethanesulfonamide) is used in the enantioselective synthesis of β-amino acids via the Mannich reaction. Used in the synthesis of sphingosine 1-phosphate-1 receptor agonists useful in pharmaceutical application.<br>References Asano, M. et al.: Tetra. Asymm., 24, 449 (2013);<br></p>

<p>Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide (E/Z mixture) is an intermediate for the synthesis of pyrrole derivatives, which are useful compounds to develop antimicrobial agents (1).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Mohamed, M. S., et al.: Acta Pharm. 59, 145 (2009)<br></p>

<p>Applications N-(3-Morpholinopropyl)-2-(p-tolyl)benzo[d]imidazo[2,1-b]thiazole-7-carboxamide is a useful synthetic intermediate in organic synthesis and pharmaceuticals.<br></p>

<p>Applications 2-Amino-N,N-dimethylbenzenesulfonamide is an intermediate used to prepare LDK378 as potent and selective anaplastic lymphoma kinase inhibitor.<br>References Marsilje, T., et al.: J. Med. Chem., 56, 5675 (2013)<br></p>

<p>Applications N-allyl-2-chloro-acetamide (cas# 13269-97-1) is a useful research chemical.<br></p>

<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>

<p>Applications N-Acetyl-N-(phenylmethyl)-propanamide is an intermediate in the synthesis of N-Ethyl-N-nitroso-1-propanamine-d4 (E817997) and isotope labelled version of N-Ethyl-N-nitroso-1-propanamine. N-Ethyl-N-nitroso-1-propanamine is a derivative of N-Nitrosodiethylamine (N525465),a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.<br>References Shirakami, Y., et al.: Bitamin, 87, 156 (2013); Fujii, Y., et al.: Toxicol., 305, 30 (2013); Uehara, T., et al.: Toxicol. Sci., 132, 53 (2013);<br></p>

<p>Applications N-Benzylformamide is a useful synthetic intermediate. It is used to prepare thiadiazolidinone derivatives as possible glycogen synthase kinase 3 inhibitors. It can also be used to synthesize selective antitubercular agents.<br>References Martinez, A., et al.: J. Med. Chem., 48, 7103 (2005); Karabanovichi, G., et al.: Eur. J. Med. Chem., 82, 324 (2014)<br></p>

<p>Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxopropanamide (cas# 87310-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N,N-Diethyl-2-bromobenzamide (cas# 76041-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(2-Hydroxyethyl)tetracosanamide acts as a crude oil emulsifier.<br>References Zhiqiang, J., et al.: Fami Zhu Shen., 5 (2016)<br></p>

<p>Applications N-Isopropylbenzenesulfonamide (cas# 5339-69-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications N-(p-Tolylsulfonylmethyl)formamide (cas# 36635-56-0) is a useful research chemical.<br></p>

<p>Applications N-(3-Aminopropyl)acetamide Hydrochloride salt is a salt form of N-Acetyl-1,3-propanediamine (A165390), which is an protected intermediate in the synthesis of analogs of Spermidine (S680400), an antineoplastic agent.<br>References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);<br></p>

<p>Applications 2-(methylamino)benzene-1-sulfonamide (cas# 21639-28-1) is a useful research chemical.<br></p>

<p>Applications N-Isobutylsorbamide shows antitubercular activity towards mycobacterium strains. It is a derivative of Sorbic Acid (S676890), a naturally occurring organic compound first isolated from unripe berries and used as a food preservative and as an inhibitor of Clostridium Botulinum bacteria in meat products.<br>References Gupta, O. et al.: Bull. Med. Ethno-Bot. Res., 1, 99 (1980); Van, M.C., et al.: Int. J. Food. Microbiol., 160, 124 (2012); Li, J., et al.: J. Am. Soc. Mass. Spec., 23, 1625 (2012);<br></p>

<p>Applications N-​(3-​Dibenzofuranyl)-​5-​nitro-2-​furancarboxamide is synthesized from Dibenzo[b,d]furan-3-amine (D418205), which is a building block used as a reactant in the preparation of dibenzofuryl(phosphonomethyl)alanines as endothelin converting enzyme inhibitors.<br>References De Lombaert, S., et al.: J. Med. Chem., 43, 488 (2000);<br></p>

<p>Applications N,N-Dibenzylformamide (cas# 5464-77-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Nitrobenzenesulfonamide (cas# 6325-93-5) is a useful research chemical.<br></p>

<p>Applications N-(2-aminoethyl)benzamide (cas# 1009-17-2) is a useful research chemical.<br></p>

<p>Applications 4-Formyl-n-isopropylbenzamide is an metabolite from the oxidation of the anti-neoplastic agent in aqueous solutions.<br>References Swaffar, D., et al.: Drug Metab. Dispos., 20, 632-642 (1992)<br></p>

<p>Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.<br>References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);<br></p>

<p>Applications 3-Bromo-benzenebutanoic Acid is a reactant used in the preparation of pyrrolo-(di)-benzazocinones via an intramolecular cyclization of N-acyliminium ions formed from 4,4-diethyoxybutyl amides (Erratum)<br>References King, F.D., et al.: Org. Biomol. Chem., 7, 5271 (2009); King, F.D., et al.: Org. Biomol. Chem., 7, 167 (2009)<br></p>

<p>Applications N-(4-Chlorophenyl)-2,6-Difluorobenzamide (cas# 122987-01-3) is a useful research chemical.<br></p>

<p>Applications N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.<br>References Lee, D. H., et al.: PCT Int. Appl. 23 pp. (2019)<br></p>

<p>Applications 4-cyano-N,N-dimethylbenzamide (cas# 24167-50-8) is a useful research chemical.<br></p>

<p>Applications N,N-Diphenyl Sulfamide is used in the preparation of aryl-substituted sulfamides.<br>References Muniz, K. et al.: Synlett 1, 149 (2005);<br></p>

<p>Applications N1,N2-Bis(4-hydroxy-2,6-dimethylphenyl)ethanediamide is an intermediate used in the synthesis of 1-Naphthol-d7 (d6 Major) (N367993), which is the isotope labelled analog of 1-Naphthol (N367990), a compound commonly used in the manufacturing of dyes, intermediates, synthetic perfumes.<br></p>

<p>Applications N-Phenyl 2-Bromo-5-Fluorobenzamide (cas# 949443-48-5) is a useful research chemical.<br></p>

<p>Applications Propiolamide (cas# 7341-96-0) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Ethyl-3-phenylpropanamide is an intermediate in the synthesis of 4-Hydroxy Alverine (H827950), a metabolite of Alverine (A575780) in plasma.<br>References Bouvier, M., et al.: Gastroenterol. Clin. Biol., 16, 334 (1992), Mitchell, S., et al.: Aliment. Pharmacol. Ther., 16, 1187 (2002), Hayase, M., et al.: Br. J. Pharmacol., 152, 1228 (2007),<br></p>

<p>Applications 3-PHENYLPROPIOLAMIDE (cas# 7223-30-5) is a useful research chemical.<br></p>

<p>Stability No Data Availabe<br>Applications 2-(4-phenyl-1,3-thiazol-2-yl)acetamide (cas# 58351-19-2) is a useful research chemical.<br></p>