Amides

Applications N,N'-(1,2-DIHYDROXYETHYLENE)BISACRYLAMIDE (cas# 868-63-3) is a useful research chemical.

Stability Light and Temperature sensitive
Applications PFPA-silane is a functionalized perfluorophenyl azides for covalent immobilization of ultrathin polymer films.
References Mosbach, K., et al.: Biotechnology, 14, 163 (1996), Keren, K., et al.: Science, 297, 72 (2002), Lidstrom, M., et al.: Nature Rev. Microbiol., 1, 158 (2003),

Applications tert-Butylsulfinamide can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. tert-Butylsulfinamide is also used as a reagent in the synthetic preparation of amide series as BACE1 inhibitor and potential anti-Alzheimer’s drug.
References Szallasi, A., et al.: Pharmacol. Rev., 51, 159 (1999), Montell, C., et al.: Mol. Cell., 9, 229 (2002), Ryu, C., et al.: Bioorg. Med. Chem. Lett., 14, 1751 (2004), Suh, Y., et al.: J. Med. Chem., 48, 5823 (2005); Woltering, T. J., et al.: Bioorg. Med. Chem. Lett., 23, 4239 (2013)

Applications 2-(Benzyloxy)acetamide

Applications 2-ethylbenzamide (cas# 67832-97-7) is a useful research chemical.

Applications (E)-2-Formamido-N-(4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)acetamide is a compound useful in organic synthesis.

Applications 4-cyano-N,N-dimethylbenzamide (cas# 24167-50-8) is a useful research chemical.

Applications o-Carbomethoxybenzyl Sulfonamide is a useful reactant in organic synthesis.
References Jiang, Lin, et al.: Youji Huaxue, 26(2), 203-206 (2006)

Applications N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.
References Lee, D. H., et al.: PCT Int. Appl. 23 pp. (2019)

Applications N-allyl-2-chloro-acetamide (cas# 13269-97-1) is a useful research chemical.

Applications 2-(2-hydroxyphenyl)acetamide (cas# 22446-40-8) is a useful research chemical.

Applications 3-Amino-2-(formylamino)-3-iminopropanamide is a Temozolomide (T017775) impurity. Temozolomide acts as a imidazotetrazine alkylating agent. An antineoplastic.
References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),

Applications Propiolamide (cas# 7341-96-0) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications N,N-Dimethylformamide Diethyl Acetal is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. Also used in the synthesis of aminopyridine derivatives.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Traxler, P. et al.: J. Med. Chem., 40, 3601 (1997); Cheikh, N. et al.: Tetrahedron, 69, 1234 (2013);

Applications Dimethylcyanamide in the presence of tetrachlorosilane and zinc chloride is used as a promoter for one-pot, three component synthesis of a novel series of 1,3-oxazines. Being a dialkylcyanamide, it has been proved to be a more reactive substrate toward metal-mediated nucleophilic addition than alkylcyanides.
References Khatab, T., et al.: Indian J. Org. Chem., 11, 215 (2015); Anisimova, T., et al.: Dalton T., 42, 12460 (2013);

Stability Light Sensitive, Moisture Sensitive
Applications N-(Hydroxymethyl)Acrylamide (cas# 924-42-5) is a useful research chemical.

Applications 2-HYDROXY-N,N-DIMETHYLACETAMIDE (cas# 14658-93-6) is a useful research chemical.

Applications N,N-Diethylacetoacetamide is an intermediate in the synthesis of Phosphamidon (E/Z mixture) (P353730), an organophosphate insecticide that acts as a cholinesterase inhibitor.
References Jacques, R., et al.: Archiv fuer Toxikologie 18: 316 (1960); Bachmann, F.: Proc. Intern. Cong. Crop. Protection, 4th Congr., 2, 1153 (1960)

Applications 4-Nitrobenzenesulfonamide (cas# 6325-93-5) is a useful research chemical.

Applications N-Benzylpropanamide is an intermediate in the synthesis of N-Ethyl-N-nitroso-1-propanamine-d4 (E817997) and isotope labelled version of N-Ethyl-N-nitroso-1-propanamine. N-Ethyl-N-nitroso-1-propanamine is a derivative of N-Nitrosodiethylamine (N525465),a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.
References Shirakami, Y., et al.: Bitamin, 87, 156 (2013); Fujii, Y., et al.: Toxicol., 305, 30 (2013); Uehara, T., et al.: Toxicol. Sci., 132, 53 (2013);

Applications N-[(4-fluorophenyl)methyl]prop-2-enamide (cas# 1046471-60-6) is a useful research chemical.

Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.

Applications 2-tert-Butylbenzenesulfonamide can be used as reactant in preparation of benzimidazole derivatives for inhibiting neoplastic cells.
References Sperl, G., et al.: U.S., US 6348032 B1 20020219 (2002)

Please enquire for more information about 2-(Diethylamino)-N-(2,4-dimethylphenyl ) acetamide HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-Desmethyl loperamide is a prodrug of loperamide, which is a peripherally acting μ-opioid receptor agonist. It has been shown to be effective in reducing the uptake of radiation in wild-type mice. This drug also inhibits p-glycoprotein (p-gp), and has been shown to reduce the uptake of pyridinium ions and amide substrates. N-Desmethyl loperamide has been shown to have anticancer properties, including resistance to radiation, inhibition of tumor growth and metastasis, and induction of apoptosis, which may be due to its ability to inhibit cellular proliferation and induce cell death. The mechanism by which this drug functions is not yet clear but it may involve inhibition of the expression or function of p-gp or other efflux pumps in cells that are sensitive to these drugs.

Benzenesulphonamide is a biologically active compound that has been shown to bind to an integrin receptor, which mediates the attachment of leukocytes to the endothelium. It also binds to a basic protein found in human immunoglobulin. Benzenesulphonamide has been shown to have cytotoxic effects on synchronous fluorescence cells and can be used for the treatment of bowel disease. This drug has also been shown to be toxic in vitro and in vivo, with a moderate acute oral toxicity and low chronic oral toxicity. Benzenesulphonamide has been shown to act as a surfactant by binding with sodium dodecyl sulfate (SDS), which is commonly used in detergents, disinfectants, shampoos, soaps, and other household products. The biological properties of benzenesulphonamide are not well-known due to its low solubility in water.

D-Leucine amide is a hydrophobic, carboxyamide amino acid that is found in the fungus Ochrobactrum anthropi. D-Leucine amide has been shown to catalyze the formation of tripeptides, such as d-alanine and d-tryptophan, from their monomers. The presence of this compound enhances the expression of genes encoding proteins involved in the synthesis of these amino acids. This compound also has been shown to enhance gene analysis by increasing the stability of DNA and RNA molecules.

Please enquire for more information about 16-Phenoxy tetranor pgf2alfa cyclopropyl methylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Formamide is a colorless, volatile chemical compound that is most commonly used in the laboratory for the preparation of dna duplexes. It can also be used to treat bowel disease and HIV infection. It is not active against viruses or bacteria but has been shown to bind to toll-like receptors on cells. Formamide is an organic substance that exists as a gas at room temperature and pressure. Formaldehyde reacts with water in the presence of sodium carbonate to form formamide, which is soluble in water. Formamide has been used as a reaction solution for surface methodology experiments because it evaporates quickly and leaves no residue on surfaces. Formamide has been shown to inhibit epidermal growth factor (EGF) activity by binding to the EGF receptor protein and preventing its activation. This inhibition leads to decreased cell proliferation, reduced protein synthesis, and inhibition of DNA replication.

2-Methylnicotinamide is an amide that is used to treat inflammatory bowel disease. It inhibits the production of glutamate and aspartate, which are neurotransmitters that are involved in the inflammation process. 2-Methylnicotinamide has been shown to have a protective effect on renal function by reducing blood flow to the kidneys, thereby decreasing renal damage caused by glutamate and aspartate. This drug also has anticancer properties, which may be due to its ability to inhibit viral replication and reduce the incidence of cancer in animals. 2-Methylnicotinamide has not yet been tested on humans, but it is thought to be safe for use in pharmaceutical dosages.

Please enquire for more information about N-(p-Hydroxyphenethyl)-N-(3-hydroxy-4-methoxybenzyl)formamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Deshydroxy bicalutamide is a ligand that has been synthesized to bind to the androgen receptor. It is an antagonist of the androgen receptor. Deshydroxy bicalutamide has been shown to inhibit cancer cell growth in prostate cancer cell lines, which is due to its ability to bind and block the ligand-binding domain of the androgen receptor. Molecular modelling has shown that deshydroxy bicalutamide binds in the hydroxyl group region of the binding site, which blocks it from binding with other ligands such as testosterone. This may lead to decreased levels of testosterone in males, leading to decreased levels of androgens in prostate cancer cells.

WAY 316606 is a potent, orally administered small molecule that inhibits the Wnt signaling pathway by blocking the action of β-catenin. It has been shown to have potential for treating eye disorders, including age-related macular degeneration. This drug also has potential for treatment of cell and nervous system diseases such as Alzheimer's disease and Huntington's disease. WAY 316606 inhibits the transcriptional activity of the β-catenin/Tcf4 complex by binding to it and preventing its translocation into the nucleus. In addition, WAY 316606 prevents downstream activation of genes regulated by β-catenin signaling, including c-myc and cyclin D1. This drug also blocks growth factor receptor tyrosine kinases and monoclonal antibodies that activate these receptors.

4-(3-Amino-2-hydroxypropoxy)phenylacetamide is a sweetener that is used as an artificial sweetener. It can be found in many foods and drinks and is often used to replace sucralose due to its lower cost. 4-(3-Amino-2-hydroxypropoxy)phenylacetamide is a white powder with a melting point of 133°C. This product has been shown to be safe for human consumption, although it may cause headaches, drowsiness, or dizziness in some people.

Dopamine (D2) receptor antagonist

Please enquire for more information about 4-Amino-1-Boc-piperidine-4-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Acetohexamide is a hypoglycemic drug that binds to the sulfonylurea receptor on pancreatic beta-cells and stimulates insulin release. It has been shown to have an oral hypoglycemic effect in humans, as well as in rats. Acetohexamide has been shown to inhibit the action of nonsteroidal anti-inflammatory drugs, such as indomethacin, through competitive inhibition. Acetohexamide also inhibits the enzyme activity of estradiol benzoate and acetohexamide hydrolase. This drug is not active against bacteria or fungi, but has been shown to be effective against some viruses. Acetohexamide is absorbed by the gastrointestinal tract and excreted unchanged in urine and feces. The drug does not bind to proteins and does not cross the blood-brain barrier.

Please enquire for more information about N,N'-Propane-1,3-diylbis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionamide] including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(3-Aminopropyl)acetamide is a secondary amine that is used as a reagent in the profiling of tissues. It has been shown to inhibit the growth of Thermus thermophilus and other bacteria, including Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. N-(3-Aminopropyl)acetamide has also been shown to inhibit the growth of cancer cells in cell culture. It was found to be effective against logarithmic growth phase cells and not against stationary phase cells. However, its mechanism of action is unknown.