Amides

Applications N,N-Dimethylthioformamide

Applications 2-Amino-2,3-dimethylbutyramide is an important intermediate in the synthesis of potent imadazoline herbicides. In addition, it is used to prepare new chiral ligands.
References Lin, Z. et al.: J. Ind. Microbiol. Biotech., 39, 133 (2012); Lin, Z. et al.: Biotech. Lett., 33, 1809 (2011); Sedlak, M. et al.: Tetra. Lett., 45, 7723 (2004);

Applications 4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.
References Sierra, M. et al.: J. Med. Chem., 50, 685 (2007); Zhong, W. et al.: Bioorg. Med. Chem. Lett., 17, 5384 (2007);

Applications Formamide is a compound that is used in biochemistry to prevent RNA samples from degradation due to RNAses. Formamide is also used as a plasticizer to prepare thermoplastic starch (TPS), a special type of starch that can be mixed with other synthetic polymers because of its unique ability to “flow”.
References Chomczynski, P.: Nuc. Acids Res., 20, 3791 (1992); Ma, X. & Yu, J.: Acta Polym. Sinica 2, No vol. given, 240 (2004); Rodriguez-Gonzalez, F., et al.: Polymer, 44, 1517 (2003); Shi, Q., et al.: Polym. Degrad. Stabil., 96, 175 (2011)

Impurity Ethinylestradiol EP Impurity I
Applications 6,7-Dehydro Ethynyl Estradiol (Ethinylestradiol EP Impurity I) is an Ethynyl Estradiol (E685100) impurity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tettey-Amlalo, R., et al.: J. Pharm. Biomed. Anal., 50, 580 (2009), Neue, U., et al.: J. Sep. Sci., 2001, 24, 921 (2001),