Amides

<p>2-Phenoxyacetamide is an acylating agent that reacts with a hydroxyl group by substitution to form an ester or amide. It is used in clinical studies to combat insulin resistance and metabolic disorders, such as cancer, inflammatory bowel disease, and diabetes. 2-Phenoxyacetamide has been shown to be effective against a number of bacterial species, including Pseudomonas aeruginosa and Cryptococcus neoformans. The drug also inhibits the production of monoamine neurotransmitters in the brain and has been shown to have anti-inflammatory properties.</p>

<p>Veratramide is a levorotatory, vanillic acid that has been synthesized by hydrolysis of esomeprazole. It is an ester of vanillic acid and hydrochloric acid. The cis-isomer is the more active form. Veratramide has been shown to be a prodrug for cisplatin, which is used in the treatment of cancer. Veratramide can also be metabolized to acetyl derivatives or flavonoids such as vitexin and metformin hydrochloride, which have anti-diabetic effects. Veratramide also binds to chloride ion channels, hypervalent ions (e.g., AlCl3), and quaternary ammonium salts (e.g., tetraethylammonium chloride).</p>

<p>4-Iodobenzenesulphonamide is a drug with antifungal and anticancer activity. The compound has been shown to inhibit the growth of cancer cells in vitro. It also has an antifungal effect in vitro, which is most likely due to its ability to inhibit the synthesis of ergosterol, a component of the cell membrane. 4-Iodobenzenesulphonamide may be used for the treatment of cervical cancer and vulvovaginal candidiasis. This drug does not show any serious side effects, but it has been shown to have some adverse effects on liver function tests and red blood cells.</p>

<p>Dodeca 2E,4E,8Z,10E,Z-tetraenoic acid isobutylamide (DETBA) is a versatile building block that is used in the synthesis of natural products and pharmaceuticals. DETBA can be used as a reaction component in organic synthesis to form complex compounds such as polyesters, polyamides, polyurethanes, and polyimides. It also has high quality and can be used in research or speciality chemical applications.</p>

<p>Morpholine-4-carboxamide is a polymerase chain inhibitor that inhibits the activity of DNA polymerases. It binds to the DNA template strand and prevents the enzyme from adding nucleotides to the primer strand, thereby inhibiting DNA synthesis. Morpholine-4-carboxamide has shown efficacy in treating hyperproliferative diseases such as cancer cells and psoriasis. This drug has been shown to inhibit caspase activation and histone protein acetylation, which may be related to its anti-cancer properties. Morpholine-4-carboxamide also binds to cannabinoid receptor 2 (CB2) and may have therapeutic effects on inflammatory diseases such as psoriasis and arthritis.</p>

<p>Propiolamide is a sulfoxide-substituted diphenyl compound that inhibits the growth of cancer cells. It is an irreversible inhibitor of the enzyme, protein kinase C, which has been shown to be involved in the regulation of cell proliferation and differentiation. Propiolamide also inhibits the production of estrone sulfate by inhibiting mitochondrial superoxide production. The hydrochloric acid-catalyzed reaction solution can be prepared using anhydrous sodium as a reducing agent and chemical stability can be achieved by using palladium as a catalyst.</p>

<p>N-[3-(3-Dimethylamino-1-oxo-2-propenyl)phenyl]-N-ethylacetamide is a high quality, complex compound that is useful as a reagent, intermediate, and building block. The CAS number for this product is 96605-66-2. This product has shown to have use in the synthesis of fine chemicals and research chemicals. It is a versatile building block that can be used as a reaction component.</p>

<p>C2 dihydroceramide is a lipid that belongs to the group of sphingolipids and is involved in neuronal death. It is a precursor for ceramide, which can also induce apoptosis. C2 dihydroceramide has been shown to inhibit axonal growth by interfering with the polymerase chain reaction, as well as inducing autophagy through toll-like receptor 4 signaling. This lipid has also been shown to inhibit intracellular Ca2+ levels, mitochondrial functions, and bowel disease. C2 dihydroceramide was identified in HL-60 cells and may be used as an analytical method for detecting other sphingolipids.</p>

<p>N-[4-(2-Hydrazino-2-oxoethoxy)phenyl]acetamide is a phenolic compound that has been shown to have an antimicrobial effect. It has been shown to have antitubercular activity against Mycobacterium tuberculosis and the ability to inhibit the growth of cancer cells in vitro. N-[4-(2-Hydrazino-2-oxoethoxy)phenyl]acetamide is also known as monastrol. The pharmacophore of this drug is based on the structure of paracetamol, which is a member of the class of drugs known as analgesics, antipyretics, and antiinflammatory agents. Paracetamol has been used for decades in humans and animals for relief from pain, fever, and inflammation. N-[4-(2-Hydrazino-2-oxoethoxy)phenyl]acetamide may be useful for treating diseases such as cancer or tuberculosis due to its antic</p>

<p>Non-steroidal androgen receptor antagonist</p>

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<p>Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is a lubricant that is used in the manufacture of polyester films. It is insoluble and has excellent compressive properties. This compound is soluble in both organic solvents and water, and can be applied as a transfer agent or to obviate the need for a separate lubricant. Heptadecafluoro-N,N-Bis(2-Hydroxyethyl)Octanesulphonamide is an inorganic material that does not react with other materials. It also has good deformation resistance and low hardness. The particle size of this compound is between 5 and 10 microns.</p>

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<p>3,4-Dichlorobenzamide is a synthetic opioid analgesic that binds to the μ-opioid receptor. It has a side-effect profile that is similar to other opioids, with an addiction risk and potential for abuse. 3,4-Dichlorobenzamide has been used in the synthesis of new drugs, such as phenazepam (a benzodiazepine) and etizolam (a thienodiazepine). This drug is chiral and can be synthesized in two stereoisomeric forms: 3-(+)-chloro-N-(2-chlorophenyl)benzamide and 3-(−)-chloro-N-(2-chlorophenyl)benzamide. The former form is marketed under the trade name Analgin, while the latter form is marketed under the trade name Etilex. The (+) form of this drug has a higher affinity for μ receptors than the (−) form.</p>

<p>5-(Acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide is a reactive iodinated contrast agent that is used in the diagnostic imaging of body cavities and blood vessels. It can be prepared by the acetylation of 5-(acetylamino)naphthalene-2,3-diol with 2,4,6-triiodobenzene dicarboxylic acid using an alkali metal as a base. The yields for this reaction are dependent on the type of solvent used. This chemical has two functional groups: an amide and an acetate group. It reacts with iohexol to form a radiocontrast product that contains both iodine and propanediol. This process is industrially carried out by mixing 5-(acetylamino)naphthalene-2,</p>

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<p>μ-opioid receptor agonist; calcium channel inhibitor; anti-diarrheal</p>

<p>Hydroxyflutamide is an anti-androgen drug that belongs to the group of nonsteroidal anti-androgens. It has been shown to bind to the androgen receptor with high affinity and inhibit the growth of cancer cells in vitro. Hydroxyflutamide also has a strong antitumor response in vivo, which is due to its ability to inhibit cellular proliferation by binding to DNA polymerase during replication. The drug may also have some activity as an antineoplastic agent because it inhibits the growth of prostate cancer cells. However, hydroxyflutamide has never been tested on humans or animals, so its effects are unknown.</p>

<p>3-Iodobenzamide is a metalloporphyrin that is used as a research tool. It has been shown to inhibit the tyrosine kinase activity of the BCR-ABL protein and to induce apoptosis in chronic myeloid leukemia cells. 3-Iodobenzamide binds to the dopamine D2 receptor, which leads to inhibition of adenylate cyclase and decreased levels of cAMP. The binding affinity of 3-iodobenzamide for dopamine receptors and its ability to inhibit cAMP production make it an ideal candidate for use in studies on striatal membrane preparations and homogenates.</p>

<p>Pantethine is a dietary supplement, which is a derivative of pantothenic acid, sourced from vitamin B5. As a biologically active compound, it undergoes conversion to pantetheine, which then forms coenzyme A (CoA) and acyl-carrier proteins. This conversion is critical, as CoA is an essential cofactor involved in numerous biochemical reactions that are integral to fatty acid metabolism, among other processes.</p>

<p>N,N-Diethylcyanoacetamide is an organic compound that is used in the industrial production of polyurethane. It reacts with a nucleophile to form a new carbon-nitrogen bond. The reaction can be monitored in real time, and it has high specificity for the desired product. N,N-Diethylcyanoacetamide reacts with piperidine to produce a mixture of isomers in which the methyl group is attached to either the nitrogen or the oxygen atom. This mixture can be separated by crystallization, and it generates a pure product that can be used as a monocarboxylic acid.</p>

<p>2-Phenyl-N-phenylacetamide is an amide that is a potent inhibitor of cholesterol acyltransferase. It has been shown to be effective in animal models of insulin resistance and hypertension, as well as in humans. 2-Phenyl-N-phenylacetamide inhibits the activity of cholesterol acyltransferase by competitive inhibition and thereby reduces the production of triglycerides. This drug also inhibits the synthesis of phospholipids and bile acids, which are important for fat digestion. 2-Phenyl-N-phenylacetamide reacts with phosphorus pentoxide to form phenoxyacetic acid, which is hydrolyzed to phenoxyacetate and phenol. The hydroxy group on phenol reacts with aryl halides to form aryl esters. These reactions lead to the formation of divalent hydrocarbon intermediates such as malonic acid, which can be used for energy production through oxidation or as precursors</p>

<p>3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide is a chemical inhibitor that inhibits the activity of kinases. It has been shown to be cytotoxic against cancer cells and to induce apoptosis through a number of different mechanisms. 3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide binds to DNA and induces DNA repair, which can lead to cell death. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit pro-inflammatory cytokines such as TNFα and IL1β.</p>

<p>2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide is an anticancer agent that inhibits the synthesis of proteins required for cell division. It has been shown to have anticancer activity and efficacy in vitro studies against human cancer cells, such as HCT116. This compound also induces apoptosis in infected cells by binding to viral particles and inducing the release of chloride ions. 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide has been found to be effective against influenza virus and particle production by inhibiting neuraminidase activity.</p>

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<p>Rink amide-AM resin is a cation exchange resin that is used in peptide synthesis. It has an optimal pH range of 8-9. Rink amide-AM resin can be activated with trifluoroacetic acid or piperidine and washed with a mixture of water and methanol to remove the salt byproduct. The resin can then be used for peptide synthesis, which is typically done by adding the desired amino acids in sequence to the resin. The synthesis is stopped when the linear peptide reaches a desired length, typically 12-15 amino acids long. The linear peptides are then cleaved from the resin using trifluoroacetic acid or piperidine, depending on which activation reagent was used during synthesis. After cleavage, the linear peptides are precipitated from solution using ethanol or acetone and collected by filtration.</p>

<p>4-Aminothiobenzamide (4ATB) is a chemical compound that is used as an anticancer agent and an antimicrobial agent. It has been shown to have antitumor activity against human liver cancer cells and anticancer activity against human adrenergic receptor-positive lung cancer cells. 4ATB binds to the chloride ion present in the cell membrane, which prevents the influx of chloride ions into the cell. This leads to an increase in intracellular pH and disruption of cellular functions. 4ATB has also been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) infections by inhibiting bacterial growth and reducing the production of proteins vital for cell division.</p>

<p>Homoveratramide is a synthetic drug that is used as an antibacterial agent. It has a broad spectrum of activity against bacteria, fungi, and protozoa. Homoveratramide has been shown to be effective against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Homoveratramide inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This produces a bacteriostatic effect on the cell by halting DNA replication and transcription.</p>

<p>Acetamide is an acyclic nucleoside phosphonate with a basic structure. Acetamide is metabolized to the corresponding ester hydrochloride, which has been shown to inhibit the polymerase chain reaction. This inhibition may be due to the effector proteins that are inactivated by acetamide, or it could be due to radiation-induced changes in the amide bond of the enzyme. Acetamide and its ester hydrochloride have been shown to inhibit skin cancer cells and carcinoma cell lines.</p>

<p>Eliglustat is an oral medication used as a substrate reduction therapy for Gaucher disease type 1, which is an inherited lysosomal storage disorder. This product is a small-molecule inhibitor derived via chemical synthesis. Its primary mode of action involves the selective inhibition of glucosylceramide synthase, an enzyme responsible for the first committed step in glycosphingolipid biosynthesis. By reducing the production of glucosylceramide, eliglustat decreases the substrate accumulation that contributes to the pathophysiology of Gaucher disease.</p>

<p>N-Chloro-4-toluenesulfonamide sodium (NCTS) is a disinfectant that is used to treat wastewater and as a preservative for water. It has been shown to be effective against bacteria, fungi, and viruses. NCTS is an antimicrobial agent that reacts with the matrix in which it is applied to form chloramines-T (NHClO). The chloramines-T inhibits the activity of enzymes such as those involved in DNA synthesis and protein synthesis. This reaction also generates an electric current due to the redox potentials of the reactants. The presence of aziridines in NCTS leads to crosslinking between proteins, which enhances its effectiveness as a disinfectant.<br>NCTS has been shown to have no adverse effects on human erythrocytes or DNA when used at concentrations up to 100 µg/mL.</p>

<p>(2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide HCl is an endogenous opioid that has been shown to have antidepressant-like effects. It can bind to γ-aminobutyric acid (GABA) receptors, catecholamine receptors, and nociceptin receptors. This drug also has anti-cancer properties and may be used for the treatment of autoimmune diseases. The interaction of this drug with other drugs is not well understood, but it has been shown to modulate the effects of opioids and increase the aversive nature of some substances.</p>

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<p>3-Chlorobenzamide is an analytical reagent that is used for the separation and purification of organic compounds. It has been shown to be a catalyst for the reaction system in the dehydration of amides, amido, and halides. 3-Chlorobenzamide has also been suggested as a possible environmental pollutant due to its catalytic properties and ability to react with monoxide. The correlations between 3-chlorobenzamide concentrations in air and soil have also been studied extensively.</p>

<p>2,6-Dichlorobenzamide is a chemical compound that belongs to the group of organochlorine compounds. It is soluble in water and has been shown to be an effective treatment for metal contamination in groundwater. 2,6-Dichlorobenzamide reacts with metal ions at the surface of cells by forming an insoluble metal chloride complex that accumulates inside the cell and leads to cell death. 2,6-Dichlorobenzamide has been shown to be toxic to bacteria, particularly gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. This compound also binds to bacterial membrane lipids with high affinity constants. This activity may be due to its ability to form lipid hydroperoxides and free radicals.</p>

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<p>2-Chloro-N-(2-nitrophenyl)acetamide is an antimicrobial agent that is a ligand for thionyl chloride. It has efficient methods of production and can be used as a bioactive molecule in the synthesis of aminosulfonyl chlorides, amide chlorides, or transfer chlorides. This compound reacts with gram-negative bacteria by hydrolyzing chloride ions to produce nitrosyl chloride and releasing hydrogen gas. The reaction time and functional groups are determined by the parameters chosen for the reaction. 2-Chloro-N-(2-nitrophenyl)acetamide has luminescence properties that can be exploited to detect the presence of chloride ions at low concentrations.</p>

<p>L-Aspartic acid beta-naphthylamide is a dietary amino acid that is metabolized to oxaloacetate in the liver. This metabolite is then converted to aspartate and glutamate, which are both important for brain functions. L-Aspartic acid beta-naphthylamide has been shown to have regulatory effects on peptide hormones, such as inhibiting the synthesis of angiotensin II and vasopressin in rats. L-Aspartic acid beta-naphthylamide also has anti-cancer properties, which may be due to its ability to inhibit the growth of cancer cells by hydrolyzing proteins and enzymes involved in fatty acid synthesis.</p>

<p>AZD 1152 is an Aurora kinase inhibitor, which is a type of small-molecule therapeutic agent. It is derived from the pharmaceutical research conducted by AstraZeneca. Its primary mode of action involves the selective inhibition of Aurora B kinase, an enzyme crucial for the regulation of mitosis. By interfering with this enzyme, AZD 1152 disrupts the normal progression of cell division, leading to the inhibition of proliferation and induction of apoptosis in rapidly dividing cells.</p>

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<p>Please enquire for more information about N-(4-Fluorophenyl)(5-methyl-3-phenylisoxazol-4-yl)formamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-alpha-Benzoyl-L-arginine amide hydrochloride (BA) is a synthetic, noncompetitive inhibitor of phosphodiesterase. It has been shown to inhibit protease activity in vitro and rhizosphere enzyme activities in vivo. BA also inhibits the formation of hippuric acid from benzoic acid, which is a reaction catalyzed by the enzyme phosphatase. The kinetics of this inhibition have been studied using a number of different substrates and enzymes. BA binds to the catalytic site on the enzyme, sterically hindering binding of the substrate and preventing hydrolysis.</p>

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<p>2-Chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide is a drug that belongs to the class of sulfonamides which is used in pharmaceutical formulations. It has been shown to have potent antihypertensive effects, and it also lowers blood pressure by inhibiting an enzyme called carbonic anhydrase. 2CCHIB binds to the chloride channel in kidney tubule cells and prevents the reabsorption of chloride ions in these cells. This leads to more water being excreted from the body, which reduces blood volume and pressure. The low density lipoprotein (LDL) cholesterol levels are also reduced when this drug is taken orally. 2CCHIB increases high sensitivity C reactive protein (hsCRP), a marker for inflammation, but it can also have antioxidant effects.</p>

<p>N-alpha-[2,4-Dinitro-5-fluorophenyl]-L-valine amide is an acidic amino acid that is used as a reagent in organic synthesis. It has been shown to have amide and hydrogen bond properties. This compound has been shown to be involved in the biosynthesis of carboxylic acids and primary amino acids. It also absorbs UV light at 265 nm and can be used for determination of uv absorption using high performance liquid chromatography (HPLC).</p>

<p>4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide HCl (PD1693) is a small molecule that has been shown to selectively inhibit the transcriptional coactivator HIF-1α. PD1693 inhibits the hypoxic response in tumor cells by preventing the upregulation of HIF-1α. This leads to an increase in hypoxia-inducible genes, which are involved in the regulation of cell proliferation, angiogenesis and apoptosis. PD1693 also affects the expression of genes involved in metabolism and energy production. The subpopulation algorithm was used to identify differentially expressed transcripts in glioma cells following exposure to PD1693. The data from this algorithm were validated using qRT-PCR and Western blotting on human glioma cells.</p>

<p>5-Benzyloxyindole-3-glyoxylamide is a versatile building block that can be used in the synthesis of complex compounds. It has been shown to have a high quality and is useful as a reagent for research purposes. 5-Benzyloxyindole-3-glyoxylamide can be used as a reaction component and is useful as an intermediate in organic synthesis. 5BIGA has CAS number 22424-62-0 and is also known as 3-(benzyloxy)-5-(2,2,2-trifluoroethoxy)indole glyoxamide.</p>

<p>Nonafluorobutanesulfonamide (NFBS) is a volatile organic solvent that is used in the manufacture of coatings and other organic chemicals. It has been shown to have a high vapor pressure, which makes it useful for drying solvents. NFBS is also used as an intermediate in the production of fluorinated acrylates and methacrylates. NFBS reacts with styrene monomers to form ionic forms, and can be converted to its neutral form by reaction with acrylonitrile or acrylates. Nonafluorobutanesulfonamide has been shown to cause liver cancer in rats, but this effect has not been observed in humans.</p>

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