Acides carboxyliques

Applications rac (Aminomethyl)ethylenediaminetetraacetic Acid tetra-(t-Butyl Ester) (cas# 1391052-55-3) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications A phosphonic acid derivative for development of biologically active compounds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ma, Q.F., et al.: Biochemistry, 29, 1412 (1990), Soti, C., et al.: Eur. J. Biochem., 270, 2421 (2003), Barabas, O., et al.: J. Biol. Chem., 279, 42907 (2004),

Applications 9-Hydroxydecanoic Acid Benzyl Ester is an intermediate in the synthesis of Monocarboxyisodecyl Phthalate (M525575), a metabolite of Dibutyl phthalate (DBP) (D429495), which is found widely in consumer products.
References Weber, A. E., et al.: J. Med. Chem., 35, 3755 (1992);

Applications 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters.
References Picard, F. et al.: J. Med. Chem., 45, 3406 (2002); Donkor, I. et al.: J. Med. Chem., 51, 4346 (2008);

Applications 5-Amino-2-chloro-4-fluorobenzoic Acid is an intermediate in the synthesis of Saflufenacil-d7 (S081802). Saflufenacil-d7 is the labeled version of Saflufenacil (S081800), which is a herbicide of the pyrimidinedione chemical class used for the preplant burndown and selective preemergence dicot weed control in different field crops. It was found to inhibit protoporphyrinogen IX oxidase (PPO) enzyme.
References Knezevic, S., et al.: Crop Prot., 29, 148 (2010); Grossmann, K., et al.: Weed Sci., 58, 1 (2010)

Applications 2-(Carboxymethylamino) Nicotinic Acid Diethyl Ester (cas# 1178176-00-5) is a compound useful in organic synthesis.

Applications Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes.
References Rafiee, M., et al.: J. Electroanal. Chem., 626, 36 (2009); Deng, J., et al.: Eur. J. Med. Chem., 46, 71 (2010)

Phenylazosalicylic acid is a crystalline solid that belongs to the group of phenylacetic acids. It is synthesized by the reaction of nitric acid with salicylic acid, which is produced from the distillation of wood. Phenylazosalicylic acid has a molecular weight of 150.09 g/mol and a melting point of 123°C. The molecule is unionized in water and can be found in wastewater effluent at concentrations as high as 3 ppm. This compound has acidic properties and reacts with picric acid to form phenylazosalicylic picrate, which is used for the treatment of anthrax. Phenylazosalicylic acid also shows proton-pumping activity, which may be due to its ability to bind to anionic sites on proteins such as carbonic anhydrase II and H+/K+ ATPase.

Quinic acid is a natural compound that is found in many plants and fruits. It has been shown to have antioxidant properties, which may be due to its ability to inhibit oxidative injury. Quinic acid also has anti-inflammatory effects and has been shown to have activity against infectious diseases such as HIV and malaria. Quinic acid can act as an enzyme activator or inhibitor depending on the type of enzyme it binds to. This property makes quinic acid a powerful tool for controlling the activity of enzymes in vitro and in vivo.

4-(Allyloxy)phenylboronic acid is an intermediate in the manufacture of pharmaceuticals and other organic compounds. It can be used as a building block for more complex compounds and as a reagent in organic synthesis. 4-(Allyloxy)phenylboronic acid is soluble in water and has a melting point of >200°C. This compound is a fine chemical with CAS No. 1117776-68-7 and is useful for research purposes.

2-(2-Methoxyphenoxy)benzoic acid is an organic compound that can be synthesized in the laboratory. It has been shown to dimerize spontaneously in aqueous solutions with the release of hydrogen peroxide and oxygen. The mechanism is thought to involve oxidative dimerization, which may lead to carboxylate bond cleavage, intramolecular radical formation, or mechanistically radical attack. This process also results in the formation of a 2-methoxyphenoxy radical.

Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.

4-Fluoro-2-hydroxybenzoic acid is an organic compound that is a proton acceptor. It can be synthesized from 2,4-dichloroaniline and hydroxylamine. 4-Fluoro-2-hydroxybenzoic acid has two isomers, one with a fluorine atom and the other without. The fluorine atom makes it more acidic than the other isomer. It also has many functional groups attached to it, including hydrogen, chlorine, and fluorine. 4-Fluoro-2-hydroxybenzoic acid is used in pesticides because of its pesticidal activity. This compound binds to receptors on pests' cells and disrupts their function.

Fmoc-(1R,2R)-2-aminocyclopentane carboxylic acid is a high quality and versatile building block. It can be used as an intermediate in the synthesis of complex compounds or as a reaction component. Fmoc-(1R,2R)-2-aminocyclopentane carboxylic acid is a speciality chemical that has potential uses in research, development and manufacturing of pharmaceuticals, agrochemicals, dyestuff intermediates, perfumes and other fine chemicals. CAS No. 359586-69-9

6a-Methyl prednisolone 21-acetate is a corticosteroid that binds to the glucocorticoid receptor, which regulates gene transcription. It has been used as an injection solution for bowel disease, but has also been shown to have anti-inflammatory and immunosuppressive effects. 6a-Methyl prednisolone 21-acetate reduces the production of inflammatory cytokines and may be a useful treatment for patients with inflammatory bowel disease (IBD). 6a-Methyl prednisolone 21-acetate has also been shown to decrease inflammation in experimental models of tissue infection, such as sepsis in mice. This drug may be useful as an adjuvant therapy for the treatment of sepsis in humans. 6a-Methyl prednisolone 21-acetate is not recommended for use in patients with congestive heart failure or severe kidney impairment because it can cause fluid retention and aggravation of these conditions.

2-Cyano-5-fluorobenzoic acid (2C5FBA) is a chemical that is synthesized by the reaction of sodium nitrite with methyl ester. It can be used in organic synthesis as a target product and can also be used as an intermediate for the synthesis of other chemicals. 2C5FBA has been shown to react with nitrogen to produce cyanide, which is toxic to humans and animals. 2C5FBA also reacts with acid methyl to produce methyl esters, which are often used as solvents in industrial settings.

Cyanuric acid is a chemical substance that is used in the manufacturing of polymer compositions. It has been shown to be an effective inhibitor of bcl-2 protein and has been used as a matrix for analytical methods such as chromatographic analysis. The compound has also been shown to have a high rate constant, which may be due to hydrogen bonding interactions with melamine. Cyanuric acid is soluble in water vapor and its biochemical properties are similar to other compounds with similar structures.

N-hydroxy-L-norarginine acetate is a chemical intermediate that can be used in high quality reagents and fine chemicals. It is also a useful scaffold for the synthesis of complex compounds. This compound is an N-hydroxy derivative of L-norarginine. It has been shown to be an effective building block for the synthesis of various compounds, including pharmaceuticals, pesticides, and other organic syntheses. N-hydroxy-L-norarginine acetate is soluble in water and alcohols, making it a versatile building block in reactions with solvent sensitive compounds.

1,3-Phenylenediacetic acid is a molecule that contains an aromatic ring and two carboxylate groups. It has been shown to react with collagen and water molecules by forming hydrogen bonds. 1,3-Phenylenediacetic acid also reacts with the hydroxyl group in the cell culture media to form a crosslink between two molecules. This reaction was found to be responsible for the observed increase in stiffness of collagen gels. The vibrational and macroscopic analysis of 1,3-phenylenediacetic acid has also revealed that it adopts a tetranuclear structure at room temperature.

Isobarbituric acid is a glycosylase that cleaves the bond between the amino group and the hydroxyl group of uridine in DNA. It has been shown to react with nucleophilic groups at neutral pH, such as an amine or hydroxyl group. Isobarbituric acid can be used to measure oxidative damage to DNA. This compound is reactive and sensitive to UV light, which makes it useful for detecting damaged DNA. Isobarbituric acid has been shown to induce neuronal death in rodents by interfering with dendritic spine formation.

1-Methyluric acid is a purine derivative that is a metabolite of caffeine. It is formed by the hepatic cytochrome P450 enzyme system and excreted in the urine. 1-Methyluric acid has been shown to be metabolized by rat liver microsomal enzymes, with the production of malonic acid, which may be responsible for its observed hepatotoxicity. The drug has also been shown to have an antibody response in rats and has been found to inhibit the activity of human liver enzymes. It also inhibits rat kidney enzyme activities and causes renal toxicity in rats. There are many drug interactions that can occur with 1-methyluric acid, including those with warfarin, phenytoin, carbamazepine, and diazepam. This drug should not be used in patients with severe renal impairment or chronic renal failure because it can cause acute renal failure due to its high degree of protein binding and rapid elimination from the body.

Tetradecyl acetate is a chemical compound that belongs to the class of pheromones. It has antioxidative properties and has been shown to have genotoxic activity, which may be due to its ability to inhibit transcriptional regulation. Tetradecyl acetate also has a strong effect on voltage-dependent calcium channels and can act as a cyclase inhibitor. This molecule is active in vivo in humans, which may be related to its ability to inhibit HIV infection.