Anneaux à 6 chaînons

Applications 4-n-Butoxybenzoic acid

Applications 5-Bromo-2-ethoxy-benzenesulfonyl chloride

Applications p-(Allyloxy)benzyl Alcohol is an intermediate in the synthesis of 2-amino-nicotinic acid benzyl ester derivatives as agrochemical fungicides.
References Jpn. Kokai Tokkyo Koho (2015), JP 2015089883 A 20150511.

Applications Methyl 5-bromo-4-chloro-2-fluorobenzoate

Applications (1R)-2-(methylamino)-1-phenylethan-1-ol (cas# 495-42-1) is a useful research chemical.

Applications Benzothiophene-5-boronic acid

Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.

Applications 4'-Dimethylaminophenyl acetylene

Applications 1-​Biphenyl-​4-​yl-​propan-​2-​one is a reactant used in the preparation of potent inhibitors of metalloproteinases 2 and 9 (MMP-2, MMP-9). This affects such processes such as homeostatic regulation, tumor progression, etc.
References Nicolotti, O. et al.: Eur. J. Med. Chem., 58, 358 (2012);

Applications 5,7-Bis-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one (cas# 23405-70-1) is a compound useful in organic synthesis.
References Smith, J., et al.: Bioorg. Med. Chem., 15, 5018 (2007),

Applications 3-Amino-4-hydroxybenzoic acid (cas# 1571-72-8) is a useful research chemical.

Applications 4-(ethenesulfonyl)benzonitrile (cas# 1154397-48-4) is a useful research chemical.

Applications N-(furan-3-ylmethyl)cyclohexanamine (cas# 462068-58-2) is a useful research chemical.

Applications DL-3-(Benzylthio)lactic Acid is used in the preparation of somatostatin analogs, affecting growth hormones.

Applications 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.
References Ye, X. et al.: Zhong. Yao. Xuax. Zaz., 20, 106 (2010);

Applications 4-(3,4-dipropoxyphenyl)-4-oxobutanoic acid (cas# 568553-00-4) is a useful research chemical.

Applications 4-Biphenylyl Glucuronide is a metabolite of 4-Phenylphenol (P3361350). 4-Phenylphenol is a reagent used in the synthesis of pyrrolo[1,2-c]imidazole dione derivatives as selective serotonin 5-HT1A receptor agonists with antinociceptive activity.
References Valhondo, M., et al.: J. Med. Chem., 56, 7851 (2013); Nichols, D., et al.: Chem. Rev., 108, 1614 (2008)

Applications 5-[2-(Trifluoromethyl)phenyl]-2-furoic Acid is a chemical reagent used in the preparation of novel TRPV1 antagonists. Also used in the preparation of potent inhibitors of FeII and MnII E, coli Methionine Aminopeptidase as antibacterial agents.
References Huguet, F. et al.: ChemMedChem. 7, 1020 (2012); Kim, N. et al.: Chem. Asian J., 8, 400 (2013);

Applications 2,6-Dimethylphenylboronic acid

Applications 3,4-Dihydroxyphenylglyoxal can be used in the preparation of adrenaline-like compounds.
References Fodor, G., et al.: Institute of Organic Chemistry of the University of Szeged, 71, 1045-1047 (1949);

Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation
References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);

Applications 2-Phenylcyclobutan-1-one (cas# 42436-86-2) is a useful research chemical.

Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.
References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),

Applications 2,3-dihydro-2,2-dimethylbenzofuran-5-carboxylic acid (cas# 123656-34-8) is a useful research chemical.

Applications Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid (V850000); a lichen metabolite with anti-inflammatory properties.
References Shachak, M., et al.: Science, 236, 1098 (1987); Froberg, L., et al.: Lichenologist, 25, 83 (1993); Hesbacher, S., et al.: J. Chem. Ecology, 21, 233 (1995)

Applications 2-(1,3-BENZOTHIAZOL-2-YLTHIO)SUCCINIC ACID (cas# 95154-01-1) is a useful research chemical.

Applications 1,2-Benzenedisulfonic Imide (cas# 4482-01-3) is a useful research chemical.

Applications N-Isopropylbenzenesulfonamide (cas# 5339-69-5) is a useful research chemical.

Applications 2,3-Dihydro-2,2,4,6,7-pentamethylbenzofuran is an 2,3-Dihydrobenzofuran derivative which is an important intermediate of medicines and agricultural chemicals.
References Kim, H. J., et al.: Hwahak Konghak, 43, 662-667 (2005)

Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.

Stability Moisture Sensitive
Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.

Applications 3-Cyclohexylbutanoic Acid (cas# 4361-38-0) is a useful reagent for the preparation of oxoheterocyclylalkyl hydroxypiperidinylketones as USP19 inhibitors for treating diseases.
References Hewitt, P., et al.: PCT Int. Appl. (2018), WO 2018020242 A1

Applications 1,2,4-Benzenetricarboxylic acid 1,2-Dihexyl Ester is a useful reagent for organic synthesis.

Applications N,N'-Bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxy-3,4,9,10-perylenetetracarboxylic Diimide has applications in the photosensors and optical detectors.
References Wang, Shaojun, et al.: ACS Photonics, 5(6), 2478-2485 (2018);Wang, Hanlin, et al.: Adv. Mat., 29(32), n/a. (2017)

Applications Alkylating agent.

Impurity Darifenacin 5 Carboxymethyl Impurity/ Darifenacin Bromo Impurity
Applications 5-(2-Bromoethyl)-2,3-dihydrobenzofuran (cas# 127264-14-6) is a compound useful in organic synthesis.

Applications (24,28),(25,27)-Bis-[8,9(3,4-dimethyl)benzo-crown-6]calix[4]arene is a metal chelator and intercalator.

Stability Dimerizes Readily - Store Under Inert Atmosphere
Applications 4-Mercaptobenzyl Alcohol, 90% (cas# 53339-53-0) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Methyl 2-(p-Tolyl)benzoate is an intermediate in the synthesis of Telmisartan (T017000) analogs.
References Ries, U., et al.: J. Med. Chem., 36, 4040 (1993), Balmforth, A., et al.: Biol. Chem., 272, 4245 (1997),

Applications N,N-Dibenzylformamide (cas# 5464-77-7) is a compound useful in organic synthesis.

Stability Air Sensitive
Applications Ethyl 2-Mercapto-1-cyclohexenecarboxylate is a reagent used in the synthesis of anti-inflammatory compounds,
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lloret, G. et al.: J. Phys. Org. Chem., 22, 1188 (2009);

Applications 5-Hydroxytoluene-2,4-disulfonic Acid acts as a synthetic reagent in the sulfonation of 2 and 3-Methylphenol.
References Strandlund, G., et al.: Acta Chem. Scand., 33, 261 (1979)

Applications N-Phenylanthranilic acid is used in biological studies for inhibitors of aldo-keto reductase 1C3 based on N-phenyl-aminobenzoates.
References Adeniji, A. O., et al.: J. Med. Chem., 55, 2311 (2012);

Applications 4-(Benzyloxy)cyclohexanol (cis / trans mixture) (cas# 2976-80-9) is a compound useful in organic synthesis.

Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.
References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)

Applications N-Hydroxybenzylamine Hydrochloride, is a versatile intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of Ticagrelor (T437700) derivatives as novel antiplatelet agents.
References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007);

Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.

Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.
References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);

Stability Smelly, Volatile product
Applications 1,4-Cyclohexadiene Monoepoxide is a synthetic intermediate. It is used as a reactant in the enantioselective formal synthesis of 4-demethoxydaunomycin. Also used in the asymmetric synthesis of β-amino and vicinal amino alcohols.
References Sekine, A., et al.: Tetrahedron, 58, 75 (2002); Carree, F., et al.: Org. Lett., 7, 1023 (2005); Arai, K., et al.: J. Am. Chem. Soc., 129, 8103 (2007);

Applications 6-Chloro-2,1,3-benzoselenadiazole (cas# 6343-86-8) is a compound useful in organic synthesis.

Applications 4-(phenylsulfanyl)phenol (cas# 5633-55-6) is a useful research chemical.

Stability Hygroscopic
Applications 5-Methylbenzotriazole intermediate.
References Vitale, G., et al.: Med. Chem., 5, 507 (2009), El-Sharief, A., et al.: Eur. J. Med. Chem., 44, 4315 (2009), Potter, A., et al.: Bioorg. Med. Chem. Lett., 20, 586 (2010),

Applications 5-Ethyl-1,3-benzenediol is a useful compound that is utilized in polycarbonate-​polyester blends. As well, it is a useful reactant for the synthesis of organic compounds such as resorcinol-​formaldehyde, and dihydroxyphthalic acids.
References Yurkevichyute, A.S., et al.: Solid Fuel Chem., 50, 64-68 (2016); Chakravarti, S., et al.: U.S.14 pp., Chemical Indexing Equivalent to 148:562759 (WO) Patent 2010 CODEN:USXXAM;

Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.
References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)

Impurity Xylometazoline EP Impurity F
Applications 2,​6-​Dimethyl-​4-​tert-​butylphenylacetic Acid is an impurity of Xylometazoline (X749950), a vasoconstrictor involved in signal transduction, also used as a nasal decongestant. May be used in treatments involving ischemic injury due to the ability to shift energy metabolism from mitochondrial to glycolysis (2).
References 1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Gohil, V. et al.: Nat Biotechnol. 2010 Mar;28(3):249-55.

Stability Moisture Sensitive
Applications 4,7-dimethyl-1,3-dihydro-2-benzofuran-1,3-dione (cas# 5463-50-3) is a useful research chemical.

Applications Methyl 2-Ethoxy-5-(ethoxysulfonyl)benzoate is a useful research chemical.

Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).
References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);

Applications (S)-4,4,7A-TRIMETHYL-5,6,7,7A-TETRAHYDROBENZOFURAN-2(4H)-ONE (cas# 15356-74-8) is a useful research chemical.

Applications 2-[hydroxy-(4-phenoxyphenyl)methylidene]propanedinitrile (cas# 330792-68-2) is a useful research chemical.

Applications 4-Dodecylbenzenesulfonic acid
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package