Anneaux à 6 chaînons

<p>Applications 1,1-Diisopropoxycyclohexane (cas# 1132-95-2) is a useful research chemical.<br></p>

<p>Applications 9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one Oxime (cas# 88909-82-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Amino(3-​chlorophenyl)​acetic Acid functions as intermediate useful in the preparation of synthetic penicillins, also used in the structure-activity relationship examination of several drugs containing the benzyl moiety, their roles in biochemical and pharmacological processes.<br>References Hansch, C., et al.: J. Med. Chem., 13, 957 (1970); Holdrege, C. T., et al.: Can. (1975), CA 966853 A2 19750429;<br></p>

<p>Stability Hygroscopic<br>Applications 4-Benzyl-morpholine-2-carboxylic is used in the synthesis of novel morpholine conjugated benzophenone analogs and evaluation of antagonistic role against neoplastic development.<br>References Al-Ghorbani, Mohammed. et al., Bioorg. Chem. 71, 55-66(2017);<br></p>

<p>Applications (S)-(+)-Benzyl Glycidyl Ether is used as a reactant in the synthesis of (+)-Discodermolide.<br>References Smith, A.B. et al.: J. Am. Chem. Soc., 122, 8654 (2000);<br></p>

<p>Applications 1-Phenyloctane is used as a solvent to study the self-assembly of derivatives of tetrathiafulvalene (TTF) on graphite and their visualization by scanning tunnelling microscopy (STM). It is also used to study the effects of the substitution of these compounds on the interactions between them.<br>References Gomar-Nadal, E., et al.: Chem. Comm.,7, 906 (2003); Shen, Y., et al.: ChemPhysChem, 14, 92 (2013)<br></p>

<p>Applications 2,4,6-Trimethylbenzenesulfonohydrazide is a reagent that generates intermediates for organic synthesis, and is applied mainly in the formation of diazine, hyrazones, Eschenmoser fragmentation and regioselective sulfonylation of pyridine/quinoline.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, R., et al.: Org. Biomol. Chem., 14, 5317 (2016); Chamberlin, A. R., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2001)<br></p>

<p>Applications A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects.<br>References Namiki, S., et al.: Bioorg. Med. Chem., 7, 1695 (1999),<br></p>

<p>Applications 5-(3,4-Dichlorophenyl)-2-furoic acid is a reactant in the preparation of dantrolene (D185000) which has a potential to treat vascular dysfunction.<br>References Ellis, K.O., et al.: J. Pharm. Sci., 69, 327 (1980); Harrison, G.G., et al.: Brit. J. Anaesth., 60, 279 (1988); Murasawa, S., et al.: Bioorg. Med. Chem., 20, 6384 (2012);<br></p>

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Applications Methyl (2S)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate<br></p>

<p>Applications N-Ethyl-3-phenylpropylamine is an intermediate in the synthesis of 4-Hydroxy Alverine (H827950), a metabolite of Alverine (A575780) in plasma.<br>References Bouvier, M., et al.: Gastroenterol. Clin. Biol., 16, 334 (1992), Mitchell, S., et al.: Aliment. Pharmacol. Ther., 16, 1187 (2002), Hayase, M., et al.: Br. J. Pharmacol., 152, 1228 (2007),<br></p>

<p>Applications 2-Nitrobenzenesulfonohydrazide (cas# 5906-99-0) is a useful research chemical.<br></p>

<p>Applications N,5-diphenyl-1,3,4-thiadiazol-2-amine (cas# 1437-57-6) is a useful research chemical.<br></p>

<p>Applications (1S)-1-(4-phenylphenyl)ethan-1-ol (cas# 150283-02-6) is a useful research chemical.<br></p>

<p>Applications (E)-5-(3,5-Bis(benzyloxy)phenyl)pent-4-en-2-ol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-[(4-fluorophenyl)methyl]prop-2-enamide (cas# 1046471-60-6) is a useful research chemical.<br></p>

<p>Applications 7-Bromo-1-benzofuran<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Store in Freezer<br>Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br></p>

<p>Applications (2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer<br>References Hutschenreuter, T. et al.: J. Enz. Inhib. Med. Chem., 19, 17 (2004);<br></p>

<p>Applications Bis(2,4,5-tribromophenyl)iodonium Hydrogen Sulfate is an intermediate in the synthesis of 2,2',4,4',5,6'-Hexabromodiphenyl ether (H290745), which is a hepatotoxic polybrominated diphenyl ester (PBDE) that is commonly used as a flame retardant. 2,2',4,4',5,6'-Hexabromodiphenyl ether is also sometimes found in food and meats as well, posing a significant risk to humans (especially during pregnancy) and/or animals that consume it. One of the new POPs under the Stockholm Convention<br>References Johnson, P., et al.: Sci. Total Environ., No vol. given, 445 (2013); Scott, L., et al.: Organo. Comp., 74, 1109 (2012); Zhao, Y., et al.: Env. Sci. Tech., 47, 5939 (2013)<br></p>

<p>Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.<br>References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)benzeneethanamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.<br>References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),<br></p>

<p>Applications 2,5-Dimethylbenzene-1,4-diol is an intermediate used in the synthesis of β-Tocopherol (Racemic Mixture) (T625170), which is one of the naturally occurring forms of Vitamins E and is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.<br>References Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003), Sakouhi, F., et al.: Food Chem., 108, 833 (2008)<br></p>

<p>Applications Glycidyl 4-Toluenesulfonate is used in the development and validation of a chiral HPLC method for rapid screening of allylic alcohol asymmetric epoxidation processes. Glycidyl 4-Toluenesulfonate is a reagent for organic displacement, additional and ring-opening reactions.<br>References Morante-Zarcero S., et al.: Analytica chimica acta, 618, 102 (2008); Bittman, R., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis; 1, (2001)<br></p>

<p>Applications (Methyl)triphenylphosphonium Iodide is the precursor to a wittig reagent.<br></p>

<p>Stability Light Sensitive<br>Applications 1,3-Cyclohexadiene (cas# 592-57-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.<br></p>

<p>Applications Methyl 2-cyanobenzoate<br></p>

<p>Impurity Ketoprofen EP Impurity G<br>Applications 3-​(2-Hydroxyethyl)​benzoic Acid (Ketoprofen EP Impurity G) is an impurity in the synthesis of Ketoprofen (K200800), anti-inflammatory (1,2); analgesic.<br>References 1. Ueno, K. et al.: J Med Chem. 1976 Jul;19(7):941-6. 2. Jamali, F. et al.: Clin Pharmacokinet. 1990 Sep;19(3):197-217.<br></p>