Anneaux à 6 chaînons

<p>Applications Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (cas# 84246-49-1) is a compound useful in organic synthesis.<br></p>

<p>Applications (2S,2aR,2aS,8aR)-2a-(2-((Cyclopropylmethyl)(methyl)amino)ethyl)-2,4,8a-trihydroxy-2,2a,8a-tetrahydro-1H-indeno[1,7,6-bcd]benzo-2-carboxylic Acid is an intermediate used in the synthesis of (4R,4aS,6S,6aR,11bS)-6-Carboxy-3-(cyclopropylmethyl)-1,2,3,4,4a,5,6,6a-octahydro-4a,6,8-trihydroxy-3-methyl-4,11-methanobenzofuro[3',2':2,3]cyclopenta[1,2-c]pyridinium, Inner Salt (C176953), which is an impurity/degradation of N-methyl Naltrexone (M320350), a metabolite of Naltrexone (N285750).<br>References Wall, M., et al.: Drug Metab. Dispos., 12, 677 (1984), Jones, D., et al.: .: Bioorg. Med. Chem., 13, 6727 ( 2005), Chen, T., et al.: Drugs Future, 32, 771 (2007); Chem. and Eng. News p.4 Jan. 23, (2017)<br></p>

<p>Applications 2,3-Dimethylbenzothiazolium Methyl Sulfate (cas# 2038-15-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation<br>References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);<br></p>

<p>Applications 1,2-Benzenedisulfonic Imide (cas# 4482-01-3) is a useful research chemical.<br></p>

<p>Applications 2,3-Dihydro-2,2,4,6,7-pentamethylbenzofuran is an 2,3-Dihydrobenzofuran derivative which is an important intermediate of medicines and agricultural chemicals.<br>References Kim, H. J., et al.: Hwahak Konghak, 43, 662-667 (2005)<br></p>

<p>Applications 2-(2-hydroxyphenyl)acetamide (cas# 22446-40-8) is a useful research chemical.<br></p>

<p>Applications Alkylating agent.<br></p>

<p>Impurity Darifenacin 5 Carboxymethyl Impurity/ Darifenacin Bromo Impurity<br>Applications 5-(2-Bromoethyl)-2,3-dihydrobenzofuran (cas# 127264-14-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Dimerizes Readily - Store Under Inert Atmosphere<br>Applications 4-Mercaptobenzyl Alcohol, 90% (cas# 53339-53-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N,N-Dibenzylformamide (cas# 5464-77-7) is a compound useful in organic synthesis.<br></p>

<p>Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.<br>References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);<br></p>

<p>Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.<br>References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);<br></p>

<p>Applications 6-Chloro-2,1,3-benzoselenadiazole (cas# 6343-86-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy.<br>References Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008); Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004);<br></p>

<p>Applications 2-[hydroxy-(4-phenoxyphenyl)methylidene]propanedinitrile (cas# 330792-68-2) is a useful research chemical.<br></p>

<p>Applications N-Benzylaniline is a major metabolite of the antihistaminic Antazoline and other N-substituted benzylanilines.<br>References Ali, H.M. et al.: J. Chrom., 202, 287 (1980); Kucukguzel, I. et al.: J. Fac. Pharm. Istan. Univ., 32, 69 (1998);<br></p>

<p>Applications (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Irinotecan (I767500) and Camptothecin (C175150) analogs.<br>References Hsiang, Y., et al.: J. Biol. Chem., 260, 14873 (1985), Bao, Y., et al.: Chin. J. Med. Chem., 18, 263 (2008), Miao, Z., et al.: Bioorg. Med. Chem., 16, 1493 (2008),<br></p>

<p>Applications 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate (cas# 99-43-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Maltol Benzyl Ether is intermediate of Malto (M160130), an fragrance molecule used in flavor enhancers and fragrances.<br>References Saghaie, L., et al.: Res. Pharma. Sci., 8, 185 (2013);<br></p>

<p>Applications 1,1-Diisopropoxycyclohexane (cas# 1132-95-2) is a useful research chemical.<br></p>

<p>Applications 9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one Oxime (cas# 88909-82-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4'-Dithiobisbenzoic Acid Dimethyl Ester (cas# 35190-68-2) is a compound useful in organic synthesis.<br></p>

<p>Applications A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects.<br>References Namiki, S., et al.: Bioorg. Med. Chem., 7, 1695 (1999),<br></p>

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Stability Light Sensitive<br>Applications Ethyl 2,3-dibromo-3-phenylpropionate<br></p>

<p>Applications Intermediate in the production of Gallic Acid derivatives.<br>References Dodo, K., et al.: Bioorg. Med. Chem., 16, 7975 (2008), Dodo, K., et al.: Chem. Pharm. Bull., 57, 190 (2009),<br></p>

<p>Applications 2-Nitrobenzenesulfonohydrazide (cas# 5906-99-0) is a useful research chemical.<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>