Étalons pharmaceutiques
Les standards pharmaceutiques sont un ensemble complet de matériaux de référence essentiels pour garantir la sécurité, l'efficacité et la qualité des produits pharmaceutiques. Cette catégorie comprend des standards pour les ingrédients pharmaceutiques actifs (APIs), qui sont les composants principaux responsables des effets thérapeutiques. De plus, elle couvre les composés et métabolites pertinents pour les industries pharmaceutique et vétérinaire, fournissant des points de référence pour la mesure et l'analyse précises de ces substances. Les standards de contrôle des nitrosamines sont cruciaux pour détecter et atténuer les nitrosamines potentiellement nocives dans les formulations médicamenteuses. Les standards de toxicologie aident à évaluer la sécurité et les effets indésirables potentiels des composés pharmaceutiques. En outre, les standards pour les activateurs et les inhibiteurs enzymatiques sont essentiels pour la recherche et le développement, permettant des études précises des voies biochimiques et des mécanismes des médicaments. Ces standards pharmaceutiques sont des outils indispensables pour la conformité réglementaire, le contrôle de qualité et la recherche, garantissant que les produits pharmaceutiques répondent à des critères stricts de sécurité et d'efficacité.
Sous-catégories appartenant à la catégorie "Étalons pharmaceutiques"
- APIs pour la recherche et les impuretés(273.774 produits)
- Activateurs et inhibiteurs d'enzymes(2.827 produits)
- Nitrosamines(2.606 produits)
- Composés et métabolites pharmaceutiques et vétérinaires(2.613 produits)
- Toxicologie(13.652 produits)
7836 produits trouvés pour "Étalons pharmaceutiques"
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3-Iodopropylene-1-naphthalene Methyl Amine
CAS :Produit contrôlé<p>Applications 3-Iodopropylene-1-naphthalene Methyl Amine (cas# 1076198-32-7) is a compound useful in organic synthesis.<br></p>Formule :C14H14INCouleur et forme :NeatMasse moléculaire :323.179-Anthracenepropan-1’-one 1’-(4’-Methylbenzene)
Produit contrôlé<p>Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).<br></p>Formule :C24H20OCouleur et forme :NeatMasse moléculaire :324.42Gibberellic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications Gibberellic Acid Methyl Ester is a derivative of the plant hormone Gibberellin which regulates growth and various developmental processes.<br>References Stolp, C.F., et al.: Plant Cell Physiol, 18, 721-8 (1977)<br></p>Formule :C20H24O6Couleur et forme :NeatMasse moléculaire :360.4cis-(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-naphthalen-1-ol-d4
CAS :Produit contrôlé<p>Applications cis-(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-naphthalen-1-ol-d4 (cas# 1217717-42-4) is a compound useful in organic synthesis.<br></p>Formule :C16H10D4Cl2OCouleur et forme :NeatMasse moléculaire :297.211-(1-Naphthyl)ethylamine
CAS :Produit contrôlé<p>Applications 1-(1-Naphthyl)ethylamine is used in the enzymic resolution of amines. A chirality modifier.<br>References Kitaguchi, H., et al.: Ann. N. Y. Acad. Sci., 613, 656 (1990); Lee I., et al.: J. Am. Chem. Soc., 130, 14597 (20008)<br></p>Formule :C12H13NCouleur et forme :NeatMasse moléculaire :171.24trans Resveratrol Penta-O-acetyl-4’-β-D-glucuronide Methyl Ester
CAS :Produit contrôlé<p>Applications Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol<br>References Learmonth, D.A., et al.: Bioconjug. Chem., 14, 262 (2003),<br></p>Formule :C31H32O14Couleur et forme :NeatMasse moléculaire :628.582-Fluoro-a-[(trimethylsilyl)oxy]benzeneacetonitrile
CAS :Produit contrôlé<p>Applications 2-Fluoro-α-[(trimethylsilyl)oxy]benzeneacetonitrile is an intermediate in synthesizing 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone (C989465), a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.<br>References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009<br></p>Formule :C11H14FNOSiCouleur et forme :NeatMasse moléculaire :223.328-Bromo-3’,5’-Di-O-tert-butyldimethylsilyl-2’-deoxyguanosine
CAS :Produit contrôlé<p>Applications 8-Bromo-3’,5’-Di-O-tert-butyldimethylsilyl-2’-deoxyguanosine is a compound useful in organic synthesis.<br></p>Formule :C22H40BrN5O4Si2Couleur et forme :NeatMasse moléculaire :574.659N-Ethyl-N-methyl-O-(4-nitrophenyl)carbamate
CAS :Produit contrôlé<p>Applications N-Ethyl-N-methyl-O-(4-nitrophenyl)carbamate (cas# 90870-20-5) is a compound useful in organic synthesis.<br></p>Formule :C10H12N2O4Couleur et forme :NeatMasse moléculaire :224.215'-Methoxylaudanosine-13C
CAS :Produit contrôlé<p>Applications Intermediate for the synthesis of neuromuscular blocking agents.<br></p>Formule :C2113CH29NO5Couleur et forme :NeatMasse moléculaire :388.469-[2-(Diethylphosphonomethoxy)propyl-d6] Adenine
CAS :Produit contrôlé<p>Applications A deuterated acyclic phosphonate nucleotide.<br></p>Formule :C132H6H16N5O4PCouleur et forme :NeatMasse moléculaire :349.36(1S,2S)-1,2-Cyclopropanedicarboxylic Acid 1,2-Diethyl Ester
CAS :Produit contrôlé<p>Applications (1S,2S)-1,2-Cyclopropanedicarboxylic Acid 1,2-Diethyl Ester is an intermediate in synthesizing (O846925), (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.<br>References Lee, J. et al.: Bioorg. Med. Chem. Lett., 22, 1340 (2012); Carmi, C. et al.: J. Med. Chem., 53, 2038 (2010); Hillaert, U. et al.: Angew. Chem. Int. Ed., 48, 1629 (2009);<br></p>Formule :C9H14O4Couleur et forme :NeatMasse moléculaire :186.205L-Aspartic Acid 1-tert-Butyl Ester
CAS :Produit contrôlé<p>Applications (3S)-3-Amino-4-tert-butoxy-4-oxobutanoic Acid (cas# 4125-93-3) is a useful research chemical.<br></p>Formule :C8H15NO4Couleur et forme :NeatMasse moléculaire :189.212’,3’,5’-Tri-O-benzoyl-2-thiouridine
CAS :Produit contrôlé<p>Applications Protected 2-Thiouridine.<br>References El-Tayeb, A., et al.: J. Med. Chem., 49, 7076 (2006),<br></p>Formule :C30H24N2O8SCouleur et forme :NeatMasse moléculaire :572.585(2R)-2-(Acetylamino)butanoic Acid-d5
CAS :Produit contrôlé<p>Applications (2R)-2-(Acetylamino)butanoic Acid-d5 is an intermediate in synthesizing Methyl Ergonovine-d5 Maleate Salt (M304602), a labelled metabolite of Methysergide. Semisynthetic ergot alkaloid. Oxytocic.<br>References Mueller, L., et al.: Headache, 37, 437 (1997), de Groot, A.N., et al.: Drugs, 56, 523 (1998),<br></p>Formule :C6D5H6NO3Couleur et forme :NeatMasse moléculaire :150.187rac Propranolol b-D-Glucuronide Triacetate Methyl Ester
Produit contrôlé<p>Applications rac Propranolol β-D-Glucuronide Triacetate Methyl Ester ia an intermediate in the synthesis of rac Propranolol β-D-Glucuronide Sodium Salt which is a metabolite of Propranolol. Antihypertensive; antianginal; antiarrhythmic (class II).<br>References Reeves, P., et al.: Xenobiotica, 8, 313 (1978), Balon, K., et al.: Pharm. Res., 16, 882(1999), Lange, R., et al.: Toxicol. Lett., 131, 97 (2002),<br></p>Formule :C29H37NO11Couleur et forme :NeatMasse moléculaire :575.62-(Hydroxydiphenylmethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS :Produit contrôlé<p>Applications 2-(Hydroxydiphenylmethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of α-Zingiberene which is a sesquiterpine found in leaf glandular trichomes that is currently being evaluated for its cytotoxicity towards human tumour cell lines.<br>References Bou, D., et al.: Molecules, 18, 9477 (2013); Freitas, J., et al.: Euphytica, 127, 275 (2002)<br></p>Formule :C22H27NO3Couleur et forme :NeatMasse moléculaire :353.45cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetic Acid
CAS :Produit contrôlé<p>Applications cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetic Acid is an intermediate for the synthesis of Arterolane p-Toluenesulfonic Acid (A614161), which is an antimalaria agent.<br>References Valecha, N., et al.: Clin Infect Dis. 55, 663 (2012); Patil, C. Y., et al.: Ann Med Health Sci Res. 4, 466 (2014)<br></p>Formule :C18H26O5Couleur et forme :NeatMasse moléculaire :322.4Tolmetin-d3 Ethyl Ester
CAS :Produit contrôlé<p>Applications Intermediate for the preparation of Isotope Labelled Tolmetin.<br></p>Formule :C17H16D3NO3Couleur et forme :NeatMasse moléculaire :288.36Eugenol-d3 Methanesulfonate
CAS :Produit contrôlé<p>Applications Eugenol-d3 Methanesulfonate is an intermediate in the synthesis of Labelled Eugenol (E935640), a dental compound which shows cytotoxicity to human oral squamous cell carcinoma and oral cells. When glucosylated, this compound exhibits anti-inflammatory activity.<br>References Koh, T. et al.: In Vivo, 27, 85 (2013); Zhang, P. et al.: Arch. Pharm. Res., 36, 109 (2013);<br></p>Formule :C11D3H11O4SCouleur et forme :NeatMasse moléculaire :245.31Ranitidine-d6 Impurity B
CAS :Produit contrôlé<p>Applications 2-[[5-(Dimethylamino-d6-methyl)-2-furanyl]methylthio]ethylamineis a labelled impurity of Ranitidine (R120000).<br></p>Formule :C10H12D6N2OSCouleur et forme :NeatMasse moléculaire :220.365-Bromo-2',3',5'-tri-O-acetyluridine
CAS :Produit contrôlé<p>Applications 5-Bromo-2',3',5'-tri-O-acetyluridine (cas# 105659-32-3) is a compound useful in organic synthesis.<br></p>Formule :C15H17BrN2O9Couleur et forme :NeatMasse moléculaire :449.214-Acetamidobenzenesulfonic Acid-d4 Pyridine (Major)
CAS :Produit contrôlé<p>Applications Labelled 4-Acetamidobenzenesulfonic Acid (A141875). 4-Acetamidobenzenesulfonic Acid is a metabolite of Sulfanilic acid.<br>References McMahon, K., et al.: Food Cosmet., Toxicol., 7, 493 (1969), Chand, P., et al.: J. Med. Chem., 40, 4030 (1997),<br></p>Formule :C13H10D4N2O4SCouleur et forme :NeatMasse moléculaire :298.351-(2’,5’-Dimethoxyphenyl)-2-chloroethanone
CAS :Produit contrôlé<p>Applications 1-(2’,5’-Dimethoxyphenyl)-2-chloroethanone (cas# 1204-22-4) is a compound useful in organic synthesis.<br></p>Formule :C10H11ClO3Couleur et forme :NeatMasse moléculaire :214.656-Mercaptopurine-9-β-D-ribofuranoside 2',3',5'-Triacetate
CAS :Produit contrôlé<p>Applications 2',3',5'-Triacetate derivative of 6-Mercaptopurine-9-β-D-ribofuranoside (M257125), a substrate for adenosine deaminase.<br>References Kashida, T., et al.: Biol. Pharma. Bull., 18, 1492 (1995); Sloan, K.B., et al.: J. Pharma. Sci., 72, 372 (1983);<br></p>Formule :C16H18N4O7SCouleur et forme :NeatMasse moléculaire :410.41-[(4-Chlorophenyl)methyl]-2-oxocyclopentanecarboxylic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications 1-[(4-Chlorophenyl)methyl]-2-oxocyclopentanecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Isotope labelled Metconazole (M225795), an conazole based fungicide used for the control of black sigatoka disease on banana.<br>References Kato, A., et al.: Chem. Pharma. Bull., 43, 2152 (1995);<br></p>Formule :C14H15ClO3Couleur et forme :NeatMasse moléculaire :266.722,4,5-Trichlorophenoxyacetic Acid-d4
CAS :Produit contrôlé<p>Applications 2,4,5-Trichlorophenoxyacetic Acid-d5 is an isotope labelled analog of 2,4,5-Trichlorophenoxyacetic Acid. It is suitable for plant cell culture tested. Post-emergence herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Smith, J., et al.: Science, 203, 1090 (1979), Salunkhe, C., et al.: Plant Cell Reports, 18, 670 (1999), Jheng, F., et al.: Plant Sci., 170, 1133 (2006),<br></p>Formule :C82H4HCl3O3Couleur et forme :NeatMasse moléculaire :259.512-Ethoxy-1-[[2'-[2-(trityl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic Acid Methyl Ester-d4 (Candesartan Impurity)
CAS :Produit contrôlé<p>Impurity Candesartan Impurity<br>Applications A byproduct formed during the synthesis of labelled Candesartan.<br>References Kubo, K., et al.: J. Med. Chem., 36, 2182 (1993)<br></p>Formule :C44H32D4N6O3Couleur et forme :WhiteMasse moléculaire :700.824-Chlorobutanoic acid methyl ester
CAS :Produit contrôlé<p>Applications 4-Chlorobutanoic acid methyl ester is used as a precursor chemical for projects such as vapor deposition for attaching ionic liquid to oxide surfaces1 and the synthesis of new thiopyran-based heterocyclic systems2.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Xu, W., et al.: Angew. Chem. Int Ed., 56, 9072-9076. (2017)2. Palchykov, V.A., and al.: New J. Chem., 42, 1403 - 1412 (2018)<br></p>Formule :C5H9ClO2Couleur et forme :NeatMasse moléculaire :136.58N-(4-Methoxyphenyl)-N'-1,2,3-thiadiazol-5-yl-urea
CAS :Produit contrôlé<p>Applications N-(4-Methoxyphenyl)-N'-1,2,3-thiadiazol-5-yl-urea is an intermediate in the synthesis of N-4-Hydroxyphenyl-N'-1,2,3-thiadiazol-5-ylurea (H949385), a metabolite of Thidiazuron (T344275), a non-purine containing urea derivative with cytokinin activity.<br>References Orlikowska, T., et al.: Plant Cell Tissue Org. Cult., 59, 95 (1999), Ray, T., et al.: Mol. Biol., 6, 35 (2005), Kanwar, J., et al.: Hort Sci., 2008, 35, 35 (2008),<br></p>Formule :C20H24O5SCouleur et forme :NeatMasse moléculaire :376.467Methyl 3-Nitrophthalate
CAS :Produit contrôlé<p>Applications Methyl 3-Nitrophthalate is an intermediate in the synthesis of (αS)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-benzenemethanamine which is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis.<br>References Gan, E. et al.: BioDrugs, 27, 359 (2013); Pathan, E. et al.: Annal. Rheum. DIs., 72, 1475 (2013)<br></p>Formule :C13H18N6O3Couleur et forme :NeatMasse moléculaire :306.32o-Tolylglyoxylic-d7 Acid Methyl Ester
CAS :Produit contrôlé<p>Applications o-Tolylglyoxylic-d7 Acid Methyl Ester is an intermediate in the synthesis of Trifloxystrobin-d6 (T778902). Trifloxystrobin-d6 is a labelled analogue of Trifloxystrobin, a broad-spectrum foliar fungicide used in plant protection. Trifloxystrobin functions by inhibiting fungal spore germination.<br>References Margot, P. et al.: Bright. Crop Prot. Conf. Pest Dis., 2, 375 (1998); Karadimos, D.A. et al.: Crop Prot., 24, 23 (2005); Prom, L.K. et al.: Plant Dis., 87, 252 (2003)<br></p>Formule :C10D7H3O3Couleur et forme :NeatMasse moléculaire :185.228N-Cyano-N',S-dimethylisothiourea
CAS :Produit contrôlé<p>Applications N-Cyano-N',S-dimethylisothiourea, is a building block used in various chemical synthesis.<br></p>Formule :C4H7N3SCouleur et forme :NeatMasse moléculaire :129.183-Chloro-2,7-naphthalenedisulfonic Acid
CAS :Produit contrôlé<p>Applications 3-Chloro-2,7-naphthalenedisulfonic Acid is an intermediate used in the synthesis of 2,3,6-Trichloronaphthalene (T774070), which can bind to the aryl hydrocarbon receptor (AhR) and induce a wide range of pleotrophic effects.<br>References Petrulis, J., et al.: Toxicol. Lett., 105, 251 (1999), Hilscherova, K., et al.: Environ. Sci. Pollut. Res., 7, 159 (2000),<br></p>Formule :C10H7ClO6S2Couleur et forme :NeatMasse moléculaire :322.744’-Bromoacetophenone
CAS :Produit contrôlé<p>Applications Possess activity against positive phototaxis of Chlamydomonas cells.A fundamental starting material for organic synthesis.<br>References Evans, S., et al.: Chem. Biol. Drug. Des., 75, 333 (2010), Rajabi, L., et al.: Lett Appl Microbiol., 40, 212 (2005),<br></p>Formule :C8H7BrOCouleur et forme :NeatMasse moléculaire :199.0459,10-Dichloro-2,6-bis(bromomethyl)anthracene
CAS :Produit contrôlé<p>Applications 9,10-Dichloro-2,6-bis(bromomethyl)anthracene (cas# 887354-43-0) is a compound useful in organic synthesis.<br></p>Formule :C16H10Br2Cl2Couleur et forme :NeatMasse moléculaire :432.96(Benzamido)oxy Acetic Acid-d2
CAS :Produit contrôlé<p>Applications Hippurate analog. Inhibitor of peptidylglycine α-hydroxylating monooxygenase (PHM). Pesticide.<br>References Merkler, D. et al. Bioorgan. Med. Chem. 16, 10061 (2008)<br></p>Formule :C9H7D2NO4Couleur et forme :NeatMasse moléculaire :197.185’-Deoxy-2’,3’-O-isopropylidene-5-fluorouridine-13C,15N2
CAS :Produit contrôlé<p>Applications 5’-Deoxy-2’,3’-O-isopropylidene-5-fluorouridine-13C,15N2 is a compound useful in organic synthesis.<br></p>Formule :CC11H15F15N2O5Couleur et forme :WhiteMasse moléculaire :289.236N-(2-Hydroxy-4-nitrophenyl)phthalimide
CAS :Produit contrôlé<p>Applications N-(2-Hydroxy-4-nitrophenyl)phthalimide (cas# 117346-07-3) is a compound useful in organic synthesis.<br></p>Formule :C14H8N2O5Couleur et forme :NeatMasse moléculaire :284.22(2S,5R)-3-(Azidomethyl)-3-methyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diphenylmethyl Ester
CAS :Produit contrôlé<p>Applications (2S,5R)-3-(Azidomethyl)-3-methyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diphenylmethyl Ester is an intermediate in the synthesis of Tazobactam Sodium Salt-13C2,15N1 (T010102), which is the labelled analogue of Tazobactam Sodium Salt (T010100), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.<br>References Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991), Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001),<br></p>Formule :C43H40O15Couleur et forme :NeatMasse moléculaire :796.7693-Amino-3-oxo-propanoic Acid Phenylmethyl Ester
CAS :Produit contrôlé<p>Applications 3-Amino-3-oxo-propanoic Acid Phenylmethyl Ester is an intermediate in the synthesis of Malonuric Acid (M158100), which is produced during degradation of sodium barbiturates.<br>References Fretwurst, F., et al.: Arzneimittel-Forschung, 8, 44-50 (1958)<br></p>Formule :C11H15N5O5Couleur et forme :NeatMasse moléculaire :297.2673-Aminobenzoic-d4 Acid Methyl Ester
CAS :Produit contrôlé<p>Applications 3-Aminobenzoic-d4 Acid (A591492) derivative. It increases attractiveness when combines with sex pheromones.<br>References Maekawa, M. et al.: Appl. Entomol. Zool., 34, 9 (1999)<br></p>Formule :C82H4H5NO2Couleur et forme :NeatMasse moléculaire :155.192,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone-d2
CAS :Produit contrôlé<p>Applications Antifungal activity, particularly toward Candida albicans and Candida parapsilosis.<br>References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006)<br></p>Formule :C10H5D2F2N3OCouleur et forme :NeatMasse moléculaire :225.19α-(Phenylmethylene)-1-naphthaleneacetic Acid
CAS :Produit contrôlé<p>Applications α-(Phenylmethylene)-1-naphthaleneacetic Acid is an intermediate in the synthesis of chrysene based polycyclic aromatic ketones found in environmental gas samples of wood and coal combustion gasses, municipal incineration waste gases, diesel exhaust, Al plant workplace and urban ambient air.<br>References Dai, W., et al.: Org. Prep. Proc. Int., 29, 347 (1997);<br></p>Formule :C19H14O2Couleur et forme :NeatMasse moléculaire :274.318-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N
CAS :Produit contrôlé<p>Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase. 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is also a labelled analog of 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (B688325).<br>References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)<br></p>Formule :C2C14H18Br15NN4O8Couleur et forme :NeatMasse moléculaire :491.2263’,4’-Dihydroxy-1-phenyl-2-butanone
CAS :Produit contrôlé<p>Applications 3’,4’-Dihydroxy-1-phenyl-2-butanone (cas# 17386-89-9) is a compound useful in organic synthesis.<br>References Strader, C., et al.: J. Biol. Chem., 266, 5 (1991),<br></p>Formule :C10H12O3Couleur et forme :NeatMasse moléculaire :180.2(S)-2-(Acetylthio)-propanoic Acid
CAS :Produit contrôlé<p>Applications (S)-2-(Acetylthio)-propanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).<br>References Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)<br></p>Formule :C5H8O3SCouleur et forme :NeatMasse moléculaire :148.189-Anthracenepropanoic Acid Ethyl Ester
CAS :Produit contrôlé<p>Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).<br></p>Formule :C24H20OCouleur et forme :NeatMasse moléculaire :324.4157-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl-d5 Ester
CAS :Produit contrôlé<p>Applications 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl-d5 Ester is the unlabelled form of 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester (C315510), which is an impurity of Norfloxacin (N681000), an antibacterial agent and a contaminant of emerging concern (CECs). 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl-d5 Ester is also an intermediate in the synthesis of Norfloxacin-d5 (N681003).<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980); Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981); Holmes, B., et al.: Drugs, 30, 482 (1985)<br></p>Formule :C14D5H8ClFNO3Couleur et forme :NeatMasse moléculaire :302.744-(Ethoxycarbonyl)phenyl 2,3,4-Triacetate β-D-Glucopyranosiduronic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications 4-(Ethoxycarbonyl)phenyl 2,3,4-Triacetate β-D-Glucopyranosiduronic Acid Methyl Ester is an intermediate in the synthesis of p-Salicylic Acid 4-Glucuronide which is an anthocyanin-derived phenolic acid degraded to form 4' glucuronide of 4-hydroxybenzoic acid during simulated gastrointestinal digestion and in human liver microsome.<br>References Zhang, Q.Z., et al.: Tetrahedron/, 68l, 4194 (2012); Woodward, G.M., et al.: Molec. Nutrition. Food. Res., 55, 378 (2011);<br></p>Formule :C22H26O12Couleur et forme :NeatMasse moléculaire :482.43Sodium Naphthalene-2,6-disulfonate
CAS :Produit contrôlé<p>Applications Sodium Naphthalene-2,6-disulfonate (cas# 1655-45-4) is a useful research chemical.<br></p>Formule :C10H6Na2O6S2Couleur et forme :NeatMasse moléculaire :332.265-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole
CAS :Produit contrôlé<p>Applications 5-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole (cas# 221243-34-1) is a compound useful in organic synthesis.<br>References Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999)<br></p>Formule :C18H18N4Couleur et forme :NeatMasse moléculaire :290.366-Bromo-7-iodo-2-naphthalenecarbonitrile
CAS :Produit contrôlé<p>Applications 6-Bromo-7-iodo-2-naphthalenecarbonitrile is an intermediate in the preparation of fused aromatic phosphonates as ptp-1b inhibitors.<br>References PCT Int. Appl. (2008), WO 2008089581 A1 20080731.<br></p>Formule :C19H24O2Couleur et forme :NeatMasse moléculaire :284.393(2S)-2-Hydroxy-1-propyl Methanesulfonate
CAS :Produit contrôlé<p>Applications Used in the preparation of labeled cocaine analogs.<br>References Carroll, F.I., et al.: J. Med. Chem., 35, 2497 (1992),<br></p>Formule :C4H10O4SCouleur et forme :NeatMasse moléculaire :154.18Isobutyrylacetic Acid Methyl Ester
CAS :Produit contrôléFormule :C7H12O3Couleur et forme :ColourlessMasse moléculaire :144.175,6,7,8-Tetrahydro-1-naphthylamine
CAS :Produit contrôlé<p>Applications 5,6,7,8-Tetrahydro-1-naphthylamine is used as a reagent in the synthesis of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. 5,6,7,8-Tetrahydro-1-naphthylamine is also used as a reagent in the synthesis of benzopyrans and related compounds as inhibitors of the hypoxia inducible factor pathway.<br>References Roy, S., et al.: Eur. J. Med. Chem., 75, 426 (2014); Mooring, S.R., et al.: J. Med. Chem., 54, 8471 (2011)<br></p>Formule :C10H13NCouleur et forme :NeatMasse moléculaire :147.223',5'-Bis(Trifluoromethyl)acetophenone
CAS :Produit contrôlé<p>Applications 3',5'-Bis(Trifluoromethyl)acetophenone is a reactant that has been used in the preparation of pyrazole carboxamide derivatives with antibacterial and antifungal activity.<br>References Patil, A., et. al.: J. Chem. Pharmaceut. Res., 6, 218 (2014)<br></p>Formule :C10H6F6OCouleur et forme :NeatMasse moléculaire :256.14tert-Butyldimethylsilyloxy-5-aza-2'-deoxycytidine
Produit contrôlé<p>Applications tert-Butyldimethylsilyloxy-5-aza-2'-deoxycytidine is an intermediate in the synthesis of metabolites of Azadeoxycytidine (A796950), as neoplasm inhibitor.<br>References Cihak, A., et al.: Eur. J. Cancer, 14, 117 (1978),<br></p>Formule :C25H34O4Couleur et forme :NeatMasse moléculaire :398.535Sodium Deuteroxide (40% w/w in D2O)
CAS :Produit contrôlé<p>Applications Sodium Deuteroxide (40% w/w in D2O) (cas# 14014-06-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :DNaOCouleur et forme :Single SolutionMasse moléculaire :41.0Methyl-(4-nitrophenylethyl)-4-(nitrophenoxyethyl)amine-d4
CAS :Produit contrôlé<p>Applications Methyl-(4-nitrophenylethyl)-4-(nitrophenoxyethyl)amine-d4 (cas# 1189869-42-8) is a compound useful in organic synthesis.<br></p>Formule :C17H15D4N3O5Couleur et forme :NeatMasse moléculaire :349.37O-Acetyl Isovanillin
CAS :Produit contrôlé<p>Applications O-Acetyl Isovanillin (cas# 881-57-2) is a compound useful in organic synthesis.<br></p>Formule :C10H10O4Couleur et forme :NeatMasse moléculaire :194.18N-Nitro-S-methylisothiourea
CAS :Produit contrôlé<p>Applications N-Nitro-S-methylisothiourea is used as a reactant in the preparation of 1,5-substituted-1,3,5-hexahydrotriazine-2-N-nitroimines with insecticidal activity.<br>References Xue, S., et. al.: J Heterocyciic Chem., 50, 1067 (2013)<br></p>Formule :C2H5N3O2SCouleur et forme :NeatMasse moléculaire :135.141-Oxyl-2,2,5,5-tetramethyl-∆3-pyrrolinyl-4-pyridine Disulfide
Produit contrôlé<p>Applications A highly reactive thiol-specific spin-label. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.<br></p>Formule :C14H19N2OS2Couleur et forme :NeatMasse moléculaire :295.443(+)-2-Hydroxypinocamphone
CAS :Produit contrôlé<p>Applications (+)-2-Hydroxypinocamphone is an essential oil of inflorescence and leaf of various species of Thymus L. These essential oils were shown to be useful for medical, flavoring and food preservation purposes.<br>References Hoeferi, M., et al.: Ernahrung., 37, 197 (2013);<br></p>Formule :C10H16O2Couleur et forme :NeatMasse moléculaire :168.23Isopropenyl Acetate
CAS :Produit contrôlé<p>Applications Isopropenyl Acetate, is an enol acetate of acetone. It is used as a solvent for cellulose, plastics, oil and fats. It is also a building block used for various organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Walters, M., et al.: e-EROS Encyclopedia of Reag. for Organ. Synth.(2001);<br></p>Formule :C5H8O2Couleur et forme :NeatMasse moléculaire :100.11582-(Formylamino)-3-hydroxy-2-propenoic Acid Ethyl Ester
CAS :Produit contrôlé<p>Applications 2-(Formylamino)-3-hydroxy-2-propenoic Acid Ethyl Ester (cas# 61934-93-8) is a compound useful in organic synthesis.<br></p>Formule :C6H9NO4Couleur et forme :NeatMasse moléculaire :159.14N-(Methoxycarbonyl)-L-glutamic Acid 5-Ethyl Ester
CAS :Produit contrôlé<p>Applications N-(Methoxycarbonyl)-L-glutamic Acid 5-Ethyl Ester is an intermediate in synthesizing (S)-Vigabatrin (V253000), a novel anti-epileptic drug. Antidepressant; antipsychotic; anxiolytic.<br>References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000); Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004); Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006);<br></p>Formule :C9H15NO6Couleur et forme :NeatMasse moléculaire :233.22β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)
CAS :Produit contrôlé<p>Applications Intermediate used in the addition of protected Glucopyranuronic Acid.<br></p>Formule :C20H21NO14Couleur et forme :NeatMasse moléculaire :499.382-Acetamido-6-chloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS :Produit contrôlé<p>Applications 2-Acetamido-6-chloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 137896-02-7) is a compound useful in organic synthesis.<br>References Matsuda, A., et al.: J. Med. Chem., 35, 241 (1992),<br></p>Formule :C18H20ClN5O8Couleur et forme :NeatMasse moléculaire :469.832-(4’-Acetyl-2-fluoro-biphenyl-4-yl)-propionic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications An intermediate for the synthesis of the metabolite of Flurbiprofen, an anti-inflammatory used as an analgesic.<br></p>Formule :C18H17FO3Couleur et forme :NeatMasse moléculaire :300.32a-Pinene Oxide
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications alpha-Pinene oxide (cas# 1686-14-2) is a useful research chemical.<br></p>Formule :C10H16OCouleur et forme :NeatMasse moléculaire :152.234-Fluoro-1-naphthalenol
CAS :Produit contrôlé<p>Applications 4-Fluoro-1-naphthalenol (cas# 315-53-7) is a compound useful in organic synthesis.<br></p>Formule :C10H7FOCouleur et forme :NeatMasse moléculaire :162.16N4-Boc-N1,N2,N3-diboc Isodesmosine Chloride Tetra t-butyl Ester
CAS :Produit contrôlé<p>Applications N4-Boc-N1,N2,N3-diboc Isodesmosine Chloride Tetra t-butyl Ester is an intermediate in the synthesis of Isodesmosine Chloride Hydrate is a component of elastin. It is extremely hygroscopic and must be stored over a desiccant such as silica gel.<br>References Partridge, S., et al.: Nature, 209, 399 (1966)<br></p>Formule :C75H128N5O22Couleur et forme :NeatMasse moléculaire :1487.293',5'-Bis-O-(tert-butyldimethylsilyl)thymidine-d3
CAS :Produit contrôlé<p>Applications An intermediate in the preparation of deuterated cytidine derivatives<br>References Chamorro, C., et al.: Bioorg. Med. Chem. Lett., 11, 3085 (2001), Bornemann, B., et al.: Bioorg. Med. Chem., 14, 6235 (2006), Desbouis, D., et al.: J. Med. Chem., 51, 6689 (2008),<br></p>Formule :C22H39D3N2O5Si2Couleur et forme :NeatMasse moléculaire :473.772'-Bromoacetanilide
CAS :Produit contrôlé<p>Applications 2'-Bromoacetanilide is used as a reagent in the preparation of furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ.<br>References Pomel, V., et al.: J. Med. Chem., 49, 3857 (2006);<br></p>Formule :C8H8BrNOCouleur et forme :NeatMasse moléculaire :214.065,6-Dihydro-5,6-dihydroxyretinoic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications 5,6-Dihydro-5,6-dihydroxyretinoic Acid Methyl Ester is an intermediate in the synthesis of Ro 22-5112 (R637180), a retinoid that has been used in a QSAR analysis for the use of retinoids as a carcinogenesis inhibitor.<br>References Niculescu-Duvaz, I., et. al.: Carcinogenesis, 6, 479 (1985)<br></p>Formule :C21H32O4Couleur et forme :NeatMasse moléculaire :348.484-Nitrophenyl Phosphorodichloridate
CAS :Produit contrôlé<p>Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)<br></p>Formule :C6H4Cl2NO4PCouleur et forme :Off-White To Light YellowMasse moléculaire :255.982,4-Dichloro-5-nitropyrimidine
CAS :Produit contrôlé<p>Applications 2,4-Dichloro-5-nitropyrimidine (cas# 49845-33-2) is a compound useful in organic synthesis.<br></p>Formule :C4HCl2N3O2Couleur et forme :NeatMasse moléculaire :193.98(T-4)-Triphenyl(P,P,P-triphenylphosphine imidato-κN)-phosphorus Diphosphate
CAS :Produit contrôlé<p>Applications (T-4)-Triphenyl(P,P,P-triphenylphosphine imidato-κN)-phosphorus Diphosphate is an intermediate used in the synthesis of Ganciclovir Triphosphate Triethylamine Salt (G235030), which is an inhibitor of hepatitis B virus DNA polymerase and has shown potent antiviral activity against herpes viruses and hepadnaviruses.<br>References Rubsam, L.Z., et al.: Cancer. Res., 59, 669 (1999); Shaw, T., et al.: Hepatol., 24, 996 (1996);<br></p>Formule :C36H30NP2•H4O7P2Couleur et forme :NeatMasse moléculaire :538.58 + 177.982,2'-[Oxybis(2,1-ethanediylimino)]bis-ethanol
CAS :Produit contrôlé<p>Applications 2,2'-[Oxybis(2,1-ethanediylimino)]bis-ethanol is a useful synthetic intermediate. It is patented as one of the antibacterial oral compositions in mouthwash.<br>References Gaffar, A., et al.: U.S. (1980), US 4224309 A 19800923.<br></p>Formule :C8H20N2O3Couleur et forme :NeatMasse moléculaire :192.262-Ethyl-2,5-dihydro-4-hydroxy-3-methyl-5-oxo-2-furancarboxylic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications 2-Ethyl-2,5-dihydro-4-hydroxy-3-methyl-5-oxo-2-furancarboxylic Acid Methyl Ester is an by-product intermediate formed during the synthesis of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600), a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.<br>References Blank, I., et al.: Prog. Flav. Prec. Stud., No vol. given, 103 (1993); Guerra, P. & Yaylayan, V.: J. Agr. Food Chem., 59, 4699 (2011); Mackenzie, D. & Woolf, L.: Brit. Med. J., 1, 90 (1959); Podebrad, F., et al.: J. Inh. Metab. Dis., 22, 107 (1999)<br></p>Formule :C9H12O5Couleur et forme :NeatMasse moléculaire :200.191,2-Dihydro-benz[j]aceanthrylen-2-ol-13C2,d4 and 5,6-Dihydro-benz[e]aceanthrylen-6-ol-13C2,d4
CAS :Produit contrôlé<p>Applications Intermediate in the synthesis of polycyclic aromatic systems.<br></p>Formule :C2C18D4H10O·13C2C18D4H9OCouleur et forme :NeatMasse moléculaire :551.661N'-[(2-Chloro-5-thiazolyl)methyl]-N-nitro-carbamimidothioic Acid Methyl Ester-13C
CAS :Produit contrôlé<p>Applications N'-[(2-Chloro-5-thiazolyl)methyl]-N-nitro-carbamimidothioic Acid Methyl Ester-13C is an intermediate used in the synthesis of Clothianidin-d3,13C1(C588502), which is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.<br>References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),<br></p>Formule :CC5H7ClN4O2S2Couleur et forme :NeatMasse moléculaire :267.721(R)-(+)-Camphor-d2
CAS :Produit contrôlé<p>Applications (R)-(+)-Camphor-d2 is an intermediate in synthesizing (+)-Borneol-D3 (B675542). It is a deuterium labelled analog of (+)-Borneol, which is used for analgesia and anesthesia in traditional Chinese and Japanese medicine. (+)-Borneol has highly efficacious positive modulating action at human recombinant α1β2γ2L GABAA receptors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Granger, R.E., et. al.: Biochem. Pharmacol., 69, 1101 (2005)<br></p>Formule :C10H14D2OCouleur et forme :NeatMasse moléculaire :154.25(2S)-1-(Benzyloxycarbonyl)azetidine-2-carboxylic acid-d5
Produit contrôlé<p>Applications (2S)-1-(Benzyloxycarbonyl)azetidine-2-carboxylic acid-d5 is a useful synthetic intermediate.<br></p>Formule :C19H28O3Couleur et forme :NeatMasse moléculaire :304.4242-Bromo-1,6-dimethyl Ester Hexanedioic Acid
CAS :Produit contrôlé<p>Applications 2-Bromo-1,6-dimethyl Ester Hexanedioic Acid is an intermediate in the synthesis of 2-Hydroxyhexanedioic Acid Disodium Salt (H943015). Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects, due to deficiency of 2-ketoadipic dehydrogenase.<br>References Svendsen, J., et al.: J. Chromatogr., 337, 9 (1985); Przyrembel, H., et al.: Clin. Chim. Acta 58, 257 (1975).<br></p>Formule :C16H18NO10S·NaCouleur et forme :NeatMasse moléculaire :439.372-Naphthalenecarboxylic Acid-13C6
CAS :Produit contrôlé<p>Applications 2-Naphthalenecarboxylic Acid-13C6 (cas# 1346602-42-3) is a compound useful in organic synthesis.<br></p>Formule :C513C6H8O2Couleur et forme :NeatMasse moléculaire :178.14(2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS :Produit contrôlé<p>Applications (2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of 2’-epi-Lincomycin which is an epimer of Lincomycin (L466200) which is a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity.<br>References Le Goffic, F. et al.: J. Antimicrob. Chemother., 16, 12 (1985); Prior, C. et al.: J. Pharmacol. Exp. Therap., 255, 1170 (1990)<br></p>Formule :C16H33NO4SiCouleur et forme :NeatMasse moléculaire :331.523-Nitrophenylboronic Acid
CAS :Produit contrôlé<p>Applications 3-Nitrophenylboronic Acid is a general reagent the preparation of carbon coated copper nanoparticles and nanowires for usage in Suzuki cross coupling reactions. Also it has been used in the synthesis of oxygenated cabazoles.<br>References Mukherjee, N. et al.: Can. J. Chem., 95, 51 (2017); Kumar, K. et al.: ChemistrySelect., 1, 601 (2016);<br></p>Formule :C6H6BNO4Couleur et forme :NeatMasse moléculaire :166.93Methyl Valerimidate-d9 Hydrochloride
CAS :Produit contrôlé<p>Applications Methyl Valerimidate-d9 Hydrochloride (cas# 1030939-72-0) is a compound useful in organic synthesis.<br></p>Formule :C6H5D9ClNOCouleur et forme :NeatMasse moléculaire :160.694-Nitrophenoxyacetic Acid
CAS :Produit contrôlé<p>Applications 4-Nitrophenoxyacetic Acid is a butyl p-nitrophenyl ether metabolite. Plant growth regulatory activity.<br>References Yoshimura, H., et al.: Biochem. Pharmacol., 16, 1953 (1967); Aaberg, B.: Swedish J. Agric. Res., 10, 101 (1980)<br></p>Formule :C8H7NO5Couleur et forme :NeatMasse moléculaire :197.142,3,4-Trihydroxyacetophenone
CAS :Produit contrôlé<p>Applications 2,3,4-Trihydroxyacetophenone is used as a reagent in the synthesis of chromenone and quinolinone derivatives as potent antioxidant agents.<br>References Vats, P., et al.: Med. Chem. Res., no vol., no pp. (2014)<br></p>Formule :C8H8O4Couleur et forme :NeatMasse moléculaire :168.152-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5
CAS :Produit contrôlé<p>Applications 2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5 is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)<br></p>Formule :C17H16D5N3O2Couleur et forme :NeatMasse moléculaire :304.4Ethylene-β-ionol-d3
CAS :Produit contrôlé<p>Applications α-Ionol derivative.<br></p>Formule :C15H21D3OCouleur et forme :NeatMasse moléculaire :223.374-Hydrazinobenzoic Acid-d4 Hydrochloride
CAS :Produit contrôlé<p>Applications A labelled carcinogen.<br>References Kirkland, D., et al.: Mut. Res., Gen. Toxicol. Environ. Mutagen., 588, 70 (2005), Ahlstroem, M., et al.: J. Med. Chem., 50, 4444 (2007),<br></p>Formule :C7H5D4ClN2O2Couleur et forme :NeatMasse moléculaire :192.641-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid-13C,d3
CAS :Produit contrôlé<p>Applications 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid-13C,d3 is an intermediate in synthesizing Moxifloxacin Hydrochloride-13CD3 (M745003), a fluorinated quinolone antibacterial.<br>References Woodcock, J.M., et al.: Antimicrob. Ag. Chemother., 41, 101 (1997); Stass, H., et al.: Antimicrob. Ag. Chemother., 42, 2060 (1998)<br></p>Formule :CC13D3H8F2NO4Couleur et forme :NeatMasse moléculaire :299.249Propylthiouracil-d5 2,3,4-Tri-O-acetyl-N-β-D-glucuronide Methyl Ester
Produit contrôlé<p>Applications A protected metabolite of Propylthiouracil. Propylthiouracil N-β-D-Glucuronide (P838315) derivative.<br>References Lindsay, R. H., et al.: J. Pharm. Sci., 63 1383 (1974)Taurog, A., et al.: Endocrinology, 122, 592 (1988)<br></p>Formule :C20H21D5N2O10SCouleur et forme :NeatMasse moléculaire :491.52L-Aspartic Anhydride Hydrochloride
CAS :Produit contrôlé<p>Applications L-Aspartic Anhydride Hydrochloride is a chemical acylating reagent used in friedel-crafts reactions such as in the preparation of L-homophenylalanine.<br>References Lin, W. et al.: Synthesis, 7, 1007 (2001);<br></p>Formule :C4H5NO3·HClCouleur et forme :NeatMasse moléculaire :115.09 + 36.462'-(Methylamino)-5'-nitro-succinanilic Acid
CAS :Produit contrôlé<p>Applications 2'-(Methylamino)-5'-nitro-succinanilic Acid is an intermediate in synthesizing 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid (C367195), a degradation production of Bendamustine (B132500), which is used as an anticancer drug.<br>References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)<br></p>Formule :C11H13N3O5Couleur et forme :NeatMasse moléculaire :267.24Palbociclib 1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester
Produit contrôlé<p>Applications Palbociclib 1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester is an intermediate in synthesizing Palbociclib N-β-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Formule :C37H45N7O11Couleur et forme :NeatMasse moléculaire :763.79
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