Étalons pharmaceutiques

Stability Hygroscopic
Applications 3,​3',​3''-​(2,​4,​6-​boroxintriyl)​tris-Pyridine Hydrochloride is a compound useful in organic synthesis.

Impurity Irbesartan Bromo N2-Trityl Impurity
Stability Moisture Sensitive
Applications An intermediate in the synthesis of Losartan and Valsartan.

Applications CMPD101 is a potent and selective GRK2/3 inhibitor.
References Lowe, J.D., et al.: Mol. Pharmacol., 88, 347 (2015); Ikeda, S., et al.: PCT Int. Appl. WO 2007034846 A1 20070329. Mar 29, 2007

Applications An intermediate of Rosuvastatin (R700500).
References Laufer, S., et al.: J. Med. Chem., 45, 2733 (2002), Palani, A., et al.: Bioorg. Med. Chem. Lett., 13, 709 (2003),

Applications 1-(4-Nitrophenyl)cyclopentanecarbonitrile-d8 is an intermediate used in the synthesis of Apatinib-d8 Hydrochloride (A726152), which is labelled Apatinib (A726150). Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
References Mi, Y. et al.: Cancer Res., 70, 7981 (2010); Tong, X.Z. et al.: Biochem. Pharmacol., 83, 586 (2012); Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012);

Stability Hygroscopic
Applications 4-Amino-4'-nitrostilbene-2,2'-disulfonic Acid Disodium Salt (cas# 6634-82-8) is a compound useful in organic synthesis.
References Taylor, A., et al.: Biochem., 38, 11172 (1999),

Applications 3,3'-Bis(methylthio)-2,2'-bithiophene is a useful reagent for organic synthesis and other chemical processes.
References Smie, A., et al.: J. Electroanal. Chem., 452, 87 (1998), Di C. N., et al.: Chem. Phys. Lett., 275, 533 (1997),

Applications Butyric acid derivative. Displays some anti-inflammatory activity.

Applications Cresyl Diphenyl Phosphate-d7 Isomer 3 is the deuterated form of Cresyl Diphenyl Phosphate (C783015), which is a phosphorus flame retardant additive.
References van der Veen., et al.: Chemosphere, 88, 1119 (2012);

Applications 5,6,7-trimethyl-2,8-dihydro-1,8-naphthyridin-2-imine (cas# 69587-84-4) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package