Étalons pharmaceutiques

Applications An labelled impurity of the commercial synthesis of labelled Raltegravir

Applications Controlled substance.

Applications γ-Valerolactone-d3 is the isotope labelled analog of γ-Valerolactone. γ-Valerolactone is a naturally occurring chemical found in fruits and is frequently used as a food additive. It can be converted to liquid alkenes which can be used as transportation fuels.
References Horvath, I.T., et al.: Green Chem., 10, 238 (2008); Bond, J.Q., et al.: Science, 327, 1110 (2010)

Applications 2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
References PCT Int. Appl. (2014), WO 2014130582 A2 20140828;

Applications Protected nucleoside.
References Elzein, E., et al.: Bioorg. Med. Chem. Lett., 17, 161 (2007), Franchetti, P., et al.: J. Med. Chem., 52, 2393 (2009),

Applications Sappanone A is a natural product flavonoid with some antioxidant properties that can be isolated from C. sappan.
References Namikoshi, M., et al.: Chem. Pharm. Bull., 35, 2761 (1987); Foroumadi, A., et al.: Bioorg. Med. Chem. Lett., 17, 6764 (2007);

Applications 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione is an intermediate in the synthesis of 7,8,9,10-Dehydro Doxorubicinone (D229580).

Applications 4-(2-Fluoro-4-nitrophenyl)morpholine is a reactant in the synthesis of 5-​substituted oxazolidinone derivatives with high antimicrobial activity.
References De Rosa, M., et. al.: Eur. J. Med. Chem., 69, 779 (2013)

Applications N1,O2'-Dimethyladenosine Monohydriodide-d3, is the labeled a analogue of N1,O2'-Dimethyladenosine Monohydriodide (D447411), is an intermediate useful in the synthesis of N6,O2'-Dimethyladenosine (D447415), which is naturally occurring modified nucleoside in RNA. It was reported in the preparation of alkylated adenosines as antihypertensive agents.
References Yamada, T., Kageyama, K.: Eur. Pat. Appl. (1988), EP 269574 A2 19880601; Aduri, R., et al.: J. Chem. Theory Comput., 3, 1464 (2007);

Applications Isotope labelled (R)-(-)-2-Oxothiazolidine-4-carboxylic Acid (O870505), a precursor to glutathione (GSH) which is an important antioxidant in plants, animals and fungi.
References Meister, A., et al,: J. Am. Coll. Nutr., 5, 137 (1986);

Applications 2,7-Dibutylnaphthalene is an intermediate in the synthesis of 3,6-Dibutyl-1-naphthalenesulfonic Acid Sodium Salt (D429485), which may be used as a coloring agent.