Étalons pharmaceutiques

Applications A new reagent that is a naphtalene analog of 4-(4'-N,N-Dimethylaminophenyl)urazole (D451750).
References Shams, E., et al.: Analitical Sci., 2002, 18, 993 ;

Applications Cholera Autoinducer 1: (3S)-3-Hydroxy-4-tridecanone is an extracellular quorum-sensing molecule which is responsible for the virulence production factor and biofilm development of Vibrio cholerae.
References Kelly, R. et al.: Nat. Chem. Biol., 12, 891 (2009);

Applications 2-Aminopyrazine-5-carboxylic Acid Methyl Ester (cas# 13924-94-2) is a compound useful in organic synthesis.

Applications 2’,4’,6’-Trihydroxy-3’,5’-diprenyldihydrochalcone, can be used in synthesis of new diterpene and new dihydrochalcone derivatives.
References Bohlmann, F., et al.: Phytochemistry (Elsevier), Vol. 19, P: 873-9 (1980);

Applications Hydrocinnamic-alpha,alpha-d2 Acid (CAS# 19136-97-1) is a useful isotopically labeled research compound.

Applications 1-(4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)phenyl)ethanone is used for the synthesis of bexarotene.
References Bhirud, S.B., et al.: PCT Int. Appl. 37pp. Patent 2011 CODEN:PIXXD2

Applications (1,2,5,6-Tetramethyl-d6)naphthalene is the labeled analogue of 1,2,5,6-Tetramethylnaphthalene (T303675), a polycyclic aromatic hydrocarbon that has been found in petroleum.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Forster, P.G., et. al.: J. Chromatogr., 483, 384 (1989)

Applications Testosterone Heptanoate-6,6,7,7,7-d5 (CAS# 1263095-31-3) is a useful isotopically labeled research compound.

Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

Applications Perchlorate salt derivative of Adenosine (A280400), nucleotide. It is also used in the synthesis of 2’-deoxy-7-methyladenosine.
References Fujii, T. et al.: Chem. Pharm. Bull., 42, 495 (1994);

Applications N-[1-(1-Naphthalenyl)ethyl]formamide is derived from 1-Acetylnaphthalene (A186940), which is used in the preparation of S(-)-1-(1'-naphthyl) ethanol, an important synthetic intermediate of mevinic acid analog;Also, it is used in the preparation of (R)-(+)-1-(1-naphthyl)ethylamine as an intermediate of cinacalcet.
References Kamble, A.L. et al.: J. Mol. Catal. B Enzym., 35, 1 (2005); Bhattacharyya, M. et al.: Biores. Technol., 98, 1958 (2007); Xu, Y., et al.: Faming Zhuanli Shenquig (2013), CN 103420845 A 20131204

Applications (S)-(-)-Malic-2,3,3-d3 Acid (CAS# 59652-74-3) is a useful isotopically labeled research compound.

Applications 1,2,3,4-Tetrahydro-1,2,5-naphthalenetriol is a a reagent used in pharmaceutical synthesis.

Applications 2,2'-Binaphthyl-d14 (CAS# 210487-05-1) is a useful isotopically labeled research compound.