Étalons pharmaceutiques

Applications A Labelled metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
References Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 958 (1998).

Applications 2-Formylcinnamic Acid (cas# 28873-89-4) is a compound useful in organic synthesis.

Applications Lodoxamide-15N2,d2 is the labelled form of Lodoxamide which is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);

Applications An impurity of the analgesic Ketorolac (K235650).

Applications 1-benzyl-3,3-dimethylthiourea (cas# 2741-14-2) is a useful research chemical.

Applications N-Carbobenzyloxy-D-serine-beta-lactone (cas# 98632-91-8) is a useful research chemical.

Applications 2-Nitrophloroglucinol is a useful synthetic intermediate. It is used to prepare benzoxazoles and benzothiazoles as selective ligands for human β-estrogen receptor (ER-β).
References Barlaam, B., et al.: PCT Int. Appl., WO 2002051821 A1 20020704 (2002)

Applications Tetramethyl-d12-urea (CAS# 51219-89-7) is a useful isotopically labeled research compound.

Applications DL-Homocysteine Thiolactone-3,3,4,4-d4 HCl (CAS# 1219805-31-8) is a useful isotopically labeled research compound.

Applications 5-Methyl-2-nitrophenol is a general chemical reagent used in the synthesis of antifungal benzoxazine-3-4(H)-one derivatives. Also used in the preparation of Levofloxacin precursors.
References Lopez-Iglesias, M. et al.: J. Org. Chem., 80, 3815 (2015);