Étalons pharmaceutiques

O-tert-Butyl-L-allo-threonine is a methionine derivative that has been shown to be expressed in the human liver and kidney. It is synthesized by coupling of the n-terminal tryptophan with O-tert-butyl L-allo-threonine, which is then followed by a transpeptidation reaction. The resulting product can be used as an efficient insulin precursor for the production of human insulin. The efficiency of this process depends on the spacer length and reaction time, which can be optimized for each synthesis.

Fmoc-O-tert-butyl-L-threoninol is an aminoacyl chloroformate ester that is used in the synthesis of peptides. It has a conjugate acid chloride and a disulfide bond. The chloroformate group reacts with the carboxylic acid moiety of L-threonine to form an ester, which can then be cleaved by hydrolysis to yield L-threonine. This product is also used for the synthesis of peptides in which the threonine residue is conjugated to another amino acid such as cysteine or glutamic acid.
Fmoc-O-tert-butyl-L-threoninol is synthesized from l-threonine and isobutene via a phase chromatography process. The synthetic intermediate Fmoc-(S)-OH is reacted with trifluoroacetic acid (TFA)

4,6-Dimethoxy-2-hydroxy-3-methylacetophenone belongs to the group of natural products. It is a phenolic compound that has been isolated from the leaves of plants in the genus Eucalyptus. 4,6-Dimethoxy-2-hydroxy-3-methylacetophenone has shown cytotoxic activity against cancer cells in an animal bioassay and inhibits tumor growth by inhibiting protein synthesis. This compound also exhibits chemosystematic properties and may be useful for research on natural products.

2,2',3,3',5,5',6,6'-Octafluorobiphenyl is a monomer that can be used for cross-coupling reactions. It can be synthesized by reacting a terminal alkyne with an organolithium compound such as cocl2. This monomer has been shown to undergo elimination reactions at lower temperatures than most other monomers and is commercially available in large quantities. 2,2',3,3',5,5',6,6'-Octafluorobiphenyl is also used as a dopant in semiconductors. The use of this compound in solar cells has been demonstrated with the addition of metal halides such as copper chloride or silver chloride. This compound has been shown to be able to efficiently absorb the light and convert it into electricity.

4-(4-Methylpiperazino)acetophenone is a chemical compound that can be used as a building block in the synthesis of more complex compounds. It is a versatile intermediate and can be used to synthesize other compounds. 4-(4-Methylpiperazino)acetophenone has been shown to act as a reaction component in the synthesis of pharmaceuticals, pesticides, and agrochemicals. This compound has high purity and quality.

3,3'-Dimethoxyazoxybenzene is a nitroarene that has electron-donating properties. It reacts with primary amines to form azoxy groups in the presence of alkoxide. 3,3'-Dimethoxyazoxybenzene can be used for the synthesis of nitrophenyl and aniline derivatives by reaction with nitroarenes, alcohols, or amines. It can also serve as a photoreduced molecule in mechanistic studies.

3,3'-Dihydroxybenzidine (DHB) is a proton-containing heterocyclic compound that is structurally related to benzidine. It is an aromatic compound with two methoxy groups and one hydroxy group. DHB is used as a reagent in the determination of phenols by measuring the formation of a yellow-colored product. The thermal stability of DHB has been shown to be greater than 80°C, which makes it useful for high temperature applications such as thermally induced DNA cleavage. When exposed to chlorine gas, DHB reacts to form chloride and hydroxy groups, which are also present in other aromatic compounds. The chemical structures of DHB can be determined using magnetic resonance spectroscopy.

Cholesterol Myristate is a fatty acid that is found in the outer membrane of cells. It has been shown to be an effective cationic surfactant and to form films at low concentrations. Cholesterol Myristate is used in the manufacture of anti-infective ointments, lotions, creams, and other skin care products. It has also been used as a film-forming polymer for cosmetic applications such as mascara and lipsticks. The phase transition temperature for cholesterol myristate is about -10°C. This means that it will not crystallize until the temperature drops below 10°C. The human serum stability of cholesterol myristate is low because the hydroxyl group interacts with water molecules, causing hydrolysis and oxidation reactions.

5-Iodocytosine (5-IC) is an analog of cytosine that can be used as a precursor for the synthesis of thymine. 5-IC has been shown to cross-couple with DNA, which may contribute to its antiviral potency. 5-IC is also a potent inhibitor of dna replication and herpes simplex virus. The biochemical properties of 5-IC have been extensively studied, including its ability to react with hydrochloric acid to form the corresponding tautomers. The hydrolysis rate increases at higher pH values and decreases at lower pH values. Bioconjugate chemistry has been applied to synthesize a bioconjugated prodrug of 5-IC for cancer treatment.

1-(3-Fluorophenyl)-2-nitropropene is a versatile building block that can be used as a reagent, speciality chemical, or a reaction component. This compound is also useful for the synthesis of complex compounds. 1-(3-Fluorophenyl)-2-nitropropene has been shown to react with various electrophiles, including carbonyl compounds and nitro compounds, to give substituted products. This chemical is classified as a high quality compound and can be used in the synthesis of pharmaceuticals and other fine chemicals.

Cresol Red Sodium Salt is a reagent, complex compound, and useful intermediate. It is CAS No. 62625-29-0 and has the molecular formula C10H8O4Na2S. It can be used as a building block for the synthesis of speciality chemicals, research chemicals, and versatile building blocks. This chemical can be used as a reaction component in organic syntheses.

4'-Chloro-3'-methylacetophenone, 95% is a white crystalline solid that is soluble in alcohols and ethers. It has been used as a reagent for the synthesis of acetophenones. The compound exhibits moderate solubility in water and reacts with aqueous alkalis to form salts. 4'-Chloro-3'-methylacetophenone, 95% also reacts with strong oxidizing agents to form peroxides and with acid chlorides to form esters.

Cimetropium bromide is a pharmacological agent that binds to muscarinic receptors, inhibiting the release of acetylcholine. It is used in the treatment of bowel disease, such as constipation and irritable bowel syndrome. Cimetropium bromide has been shown to be effective in treating symptoms of these diseases, including decreased intestinal motility, increased stool consistency, and relief from abdominal pain. Cimetropium bromide has also been found to be effective in reducing symptoms of inflammatory bowel disease. This drug inhibits the release of acetylcholine by binding with muscarinic receptors on the smooth muscle cells lining the intestine and bladder. Cimetropium bromide is a potent antimuscarinic agent that can cause dry mouth and blurred vision.