Étalons pharmaceutiques

Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Applications S-Benzoyl Tiopronin-d5 is labelled S-Benzoyl Tiopronin (B209585) which is used to prepare radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders.
References DeGrado, W., et al.: PCT Int. Appl., WO 9422494 A1 19941013 (1994)

Applications 2-Quinoxalinecarboxylic Acid Methyl Ester has been used as a reactant in the synthesis of quinoxaline derivatives that show antimycobacterial activity, while displaying minor activity itself. In addition to having the substructure that exhibits antitumor activity, it is also used in the design of guanine-guanine selective DNA cleaving agents.
References Seitz, L.E. et al.: J. Med. Chem., 45, 5604 (2002); Toshima, K. et al.: Chem. Comm., 3, 212 (2002);

Applications Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.
References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)

Applications 2'-Hydroxyflavone (cas# 35244-11-2) is a useful research chemical.

Applications N,N-Dipropyl-2-(2-methyl-3-nitrophenyl)ethylamine is an intermediate used to prepare 4-[2-(Di-n-propylamino)ethyl]-2(3H)-indolone and related compounds as a prejunctional dopamine receptor agonist.
References Gallagher, G., et al.: J. Med. Chem., 28, 1533 (1985); DeMarinis, R., et al.: J. Med. Chem., 29, 939 (1986)

Applications 1-(2-Hydroxyphenyl)-2-nitropropene (cas# 86029-73-4) is a useful research chemical.