Étalons pharmaceutiques

2,6-Dichloro-5-nitropyrimidin-4-amine is a chlorinating agent that reacts with aliphatic and aromatic amines to form substituted pyrimidines. The substitution pattern of the product depends on the regioselectivity of the reaction. 2,6-Dichloro-5-nitropyrimidin-4-amine is one of the few chlorinating agents that react with propylamine. Substitution at position 2 of the purine ring has been found to be more selective than substitution at position 6. The 2,6-dichloropyrimidine can also be used as a nitro group source in chemical synthesis or as an intermediate in production of other compounds.

Naphthalen-2-ethanol is a primary alcohol that has been synthesized and immobilized onto boron nitride. It can be used as a synthetic reaction rate indicator. Naphthalen-2-ethanol is soluble in organic solvents such as methanol, which can be used to determine the concentration of methanol in solution by observing the change in absorbance at 230 nm. This compound has functional groups such as carbinols, which are characterized by their high reactivity and ability to form esters, ethers, amides, or nitriles. Naphthalen-2-ethanol also reacts with lipases to produce polyamines and with chromatography to produce substitutive nomenclature.

Tetramethylurea is a versatile compound that has various applications in different fields. It is commonly used as a monophosphate donor in biochemical reactions and as a reagent for the synthesis of L-sorbose and histidine. In addition, tetramethylurea is employed in the production of herbicides, as well as in the synthesis of zirconium oxide nanoparticles.

3-(4-Chlorophenyl)glutaric acid is a subunit of lanthanide complexes. It has been synthesized from cinchona alkaloids and single-crystal x-ray diffraction data obtained in the absence of ligands. 3-(4-Chlorophenyl)glutaric acid is a desymmetrization reagent and has been shown to be an effective ligand for lanthanide complexes. This compound has the potential to form impurities during the synthesis process, which can lead to morphological changes, luminescence, or high-performance liquid chromatography interference.

Chloro[2-(di-tert-butylphosphino)-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl)]palladium(II) is a molecule that inhibits the adenosine receptor in autoimmune diseases and cancer. It also has an inhibitory effect on the membrane transport of glucose, glucosan, and aziridine. This drug can be used to treat inflammatory diseases such as diabetes, asthma, and inflammatory bowel disease. The geometric isomers of this molecule are not identical in shape or size and can have different effects on the body.

Please enquire for more information about Vitamin B12 c-lactone including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Nitronaphthalene is a nitrobenzene derivative that has been used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. 1-Nitronaphthalene is classified as a hazardous substance due to its carcinogenicity and toxicity. In particular, it can cause irritation and burns on skin contact and may be fatal if swallowed. The toxicity profile of 1-nitronaphthalene has been studied in rats, mice, guinea pigs, rabbits, hamsters, and dogs. It was found to have moderate acute oral toxicity in rats but no significant acute toxicity in mice or dogs. 1-Nitronaphthalene also had little effect on p450 activity or enzyme activities in rats.

1,2,3,4-Tetrahydronaphthalen-2-amine hydrobromide (THNA) is an amine that inhibits the enzyme tyrosine hydroxylase. This inhibition leads to a decrease in the synthesis of dopamine and norepinephrine. THNA has been shown to have inhibitory properties on locomotor activity, acid complex formation, and aminotransferases. It also exhibits receptor binding and agonist binding site activity. One study found that THNA had no effect on rat striatal tissue. The drug has been shown to be effective in metabolic disorders such as obesity.

Please enquire for more information about (S)-N-Fmoc-2-(3'-butenyl)glycine including the price, delivery time and more detailed product information at the technical inquiry form on this page

(S)-3',5'-Bis(trifluoromethyl)-1-phenethanol is a choline derivative that is used in the treatment of liver cancer. It has been shown to increase the permeability of cell membranes and to suppress the growth of tumor cells by inhibiting protein synthesis. (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol can be used as a surfactant and a hydrophobic solvent for optimization of reaction parameters. This chemical also has been shown to be active against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli or Pseudomonas aeruginosa. The mechanism of this effect is mediated by chloride ions that act as bioreductive agents on cellular membranes, leading to increased permeability and cell death.

4-Acetyl-1,8-naphthalic anhydride is a naphthoquinone that has been shown to have apoptosis-inducing properties. It inhibits mitochondrial electron transport and the generation of ATP, leading to cell death. 4-Acetyl-1,8-naphthalic anhydride also binds to DNA, which prevents transcription and replication. This compound can be used in vivo assays to evaluate the efficacy of anticancer drugs by determining tumor growth inhibition or the induction of apoptosis in cancer cells. The binding affinity of 4-acetyl-1,8-naphthalic anhydride for DNA is approximately two orders of magnitude higher than its affinity for other cellular components such as proteins or lipids.

Please enquire for more information about Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Boc-L-tyrosine methyl ester is a synthetic amino acid that can be used in the production of peptides and proteins. It has been shown to have a high uptake and hydroxyl group, which allows for the synthesis of dopamine. The kinetic study of Boc-L-tyrosine methyl ester in agarose gels has shown that it has a high affinity for dopamine. Boc-L-tyrosine methyl ester has also been used as an intermediate for the synthesis of peptides and proteins. It is not active against cancer cells but has been used to induce matrix metalloproteinase (MMP) activity in Mcf-7 cells.

Benzoylhypaconine is an alkaloid compound, which is a secondary metabolite typically found in certain plant species. It is primarily derived from Aconitum species, a group of plants known for their complex alkaloidal chemistry. The mode of action of benzoylhypaconine involves interactions with various receptors and enzymes in biological systems, reflecting its potential to influence neurotransmission and enzymatic activity.

Pancreastatin is a cytosolic protein that inhibits the production of peptide hormones such as glucagon, insulin, and gastrin. It is used to treat bowel disease, including carcinoid syndrome and inflammatory bowel disease. Pancreastatin has been shown to inhibit the activity of cyclase enzymes that are responsible for the production of these hormones. Pancreatic beta-cells produce pancreatic polypeptide (PP), which is converted by pancreastatin into inactive PP2. Pancreatic alpha-cells produce somatostatin (SS), which is converted by pancreastatin into inactive SS2. Pancreatic delta cells produce pancreatic polypeptide (PP), which is not affected by pancreastatin. Pancreatic somatostatinomas secrete SS, which is not affected by pancreastatin.

Cinnamtannin B-1 is a cytosolic Ca2+ modulator that binds to and inhibits the activity of ATPases, which are enzymes that hydrolyze ATP. This causes an increase in intracellular Ca2+ levels, which leads to altered cell physiology. Cinnamtannin B-1 also inhibits mitochondrial membrane potential and enzyme activities. Cinnamtannin B-1 is a bioactive phytochemical found in cinnamon extract, which has been shown to have anti-obesity effects due to its ability to reduce the number of fat cells. Cinnamtannin B-1 has been shown to inhibit 3T3-L1 preadipocyte differentiation by targeting proteins such as procyanidins.