Glycosciences

<p>1,4:6,3-Glucarodilactone is an undecenoate with a sustainable and degradable structure. It can be used as a monomer in the production of polyols that are used in various industries, such as the plastics industry. 1,4:6,3-Glucarodilactone is also an acidic compound that has been shown to have a crystalline product and isomeric transition. It is possible to produce this compound by ring-opening polymerization of p-xylylenediamine with butyl vinyl ether or isobutyl vinyl ether.</p>

<p>Cellobiuronic acid is a polysaccharide that contains glucose and uronic acids. It is found in the cell walls of gram-positive bacteria, where it may play an important role in maintaining the structural integrity of the cell wall. Cellobiuronic acid has been shown to be a potent antigen for pneumococcus. Cellobiuronic acid has also been shown to be conjugated with proteins and used as a vaccine adjuvant for inducing antibody responses against pneumococcal antigens. Cellobiuronic acid is synthesized from glucose by bacterial cells, which use it as a carbon source. The biosynthesis of cellobiuronic acid is poorly understood because it does not occur in mammalian cells.</p>

<p>Propranolol-2-O-b-D-glucuronide is a metabolite of propranolol hydrochloride. It has been shown to have low bioavailability in humans and rats. Propranolol-2-O-b-D-glucuronide is eliminated via the kidney, with an elimination rate that is faster than the parent drug propranolol hydrochloride. The glucuronide conjugate of propranolol, which is found in urine samples, has been shown to be a potential biomarker for glomerular filtration rate and renal function.</p>

<p>N-Acetyl-2-O-methyl-a-neuraminic acid methyl ester 4,7,8,9-tetraacetate is a synthetic monosaccharide that is the methyl ester of 2-O-Methyl alpha-neuraminic acid. It is an important reagent in the synthesis of oligosaccharides and polysaccharides. Methylation of the hydroxyl group on the C4' atom of NAMNAA (4,7,8,9 tetraacetate) with methyl iodide followed by acetylation with acetic anhydride produces the desired product. The resulting product has a purity level of &gt;98% and CAS No. 73208-80-7.</p>

<p>1,6:3,4-Dianhydro-2-O-p-toluenesulfonyl-b-D-galactopyranose is a fluorinated monosaccharide that can be used in glycosylation reactions. This compound can be custom synthesized and is not available commercially. It has CAS No. 6167-32-4 and its molecular weight is 489.1 g/mol.</p>

<p>Quinovic acid 3-O-b-D-glucoside is a fluorinated saccharide that has been synthesized in the laboratory. It is a high purity, synthetic sugar with an M+1 ion at m/z 571. The structure of this compound is O-α-D-mannopyranosyl-(1→2)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-O-.</p>

<p>2-C-(2,3,4,6-Tetra-O-benzyl-b-D-glucopyranosyl) ethyne is a synthetic monosaccharide. It has a molecular formula of C12H14O8 and a molecular weight of 302.24 g/mol. 2-C-(2,3,4,6-Tetra-O-benzyl-b-D-glucopyranosyl) ethyne is used to modify oligosaccharides and polysaccharides in the synthesis of complex carbohydrates. This chemical is also used as an intermediate in the fluorination reaction to produce polyfluorinated molecules with high purity.</p>

<p>Piceatannol 3'-O-glucoside is a natural compound that is found in grape seeds. It has been shown to have the ability to inhibit the activity of matrix metalloproteinase (MMP)-9, which damages the extracellular matrix and promotes tumor growth. Piceatannol 3'-O-glucoside also inhibits the expression of MMP-9 at the transcriptional level. This compound also blocks the activation of PDGF and its downstream signaling pathway, leading to decreased cell proliferation and cell death. Piceatannol 3'-O-glucoside may be a potential treatment for various diseases, such as cancer, high blood pressure, nervous system diseases, or other conditions where MMP-9 activity is increased.</p>

<p>N-{[4-(Hydroxyamino)phenyl]sulfonyl}-N-[2-(2-naphthyloxy)ethyl]-b-D-glucopyranosylamine is a small molecule that inhibits the activity of oncoproteins by binding to lysine residues. It has been shown to inhibit the growth of tumor cells in vitro and in vivo, suggesting that it may be useful for anti-cancer therapy. The binding of this compound to lysine residues is specific and does not interfere with protein synthesis or other cellular processes.</p>

<p>Tetra-O-benzyl-L-rhamnopyranoside is a modification of L-rhamnopyranoside, an oligosaccharide with the formula CHO. It is a complex carbohydrate that can be synthesized from monosaccharides and polysaccharides. Tetra-O-benzyl-L-rhamnopyranoside is a high purity, custom synthesis, and synthetic product. The product is soluble in water and has a sweet taste. Tetra-O-benzyl-L-rhamnopyranoside is used in the synthesis of saccharides, glycosylation, methylation, fluorination, and click chemistry reactions.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-[2,4,6-tri-O-acetyl-3-O-(3,4,6-tri-O-acetyl-2-deoxy-2 -phthalimido)-bDglucopyranosyl]-bDgalactopyranoside is a high purity methylated glycoside of 4 methoxyphenol. The product has been modified by fluorination and Click chemistry to produce a complex carbohydrate. This modification can be used for the synthesis of oligosaccharides and polysaccharides.</p>

<p>D-2'-Deoxyribofuranosyl-3-guanylurea is a custom synthesis that is used as an intermediate in the glycosylation of oligosaccharides and polysaccharides. D-2'-Deoxyribofuranosyl-3-guanylurea is a modified sugar that has been fluorinated, methylated, and glycosylated. This compound is used to synthesize complex carbohydrates that are important for various biological processes.</p>

<p>Methylglycol chitosan is a cationic surfactant that has been shown to have the ability to bind with zirconium oxide and polymannuronic acid. It is used in the treatment of infectious diseases, autoimmune diseases, and histological analysis. Methylglycol chitosan has been shown to inhibit the toll-like receptor 4 (TLR4) from binding with lipopolysaccharides and other molecules that are implicated in autoimmune diseases. This binding also prevents TLR4 from activating other cells involved in inflammatory responses. The surface of methylglycol chitosan particles also have a patterning effect on bacteria by preventing them from adhering to the surface of the particle, reducing their virulence.</p>

<p>Tetradecasaccharide dp14 is a custom-synthesized, fluorinated, methylated, and modified saccharide. Tetradecasaccharide dp14 has been shown to have a variety of biological activities that are dependent on the type of modification. For example, this compound inhibits the enzyme alpha-glucosidase in vitro and in vivo. This enzyme is responsible for breaking down complex carbohydrates into simple sugars. Tetradecasaccharide dp14 also has anti-inflammatory properties and can be used as an antifungal agent against Candida albicans.</p>

<p>Man-3-Xyl-Fuc N-Glycan is a custom synthesis of mannose that has been modified with fucose and glycosylated with a conjugated xylose. This complex carbohydrate can be used in the manufacturing of pharmaceuticals, as well as in research for the production of biofuels.</p>

<p>The characteristic structure of pectin is a linear chain of α-(1,4)-linked D-galacturonic acid that forms the pectin-backbone, a homogalacturonan (pectic acid). The polygalacturonic acid is partly esterified with methyl groups and the free acid groups may be partly or fully neutralized with sodium, potassium or ammonium ions. The ratio of esterified galacturonic acid groups to total galacturonic acid groups - termed the degree of esterification (DE) - has vital influence on the properties of pectin, especially the solubility and the gel forming characteristics. The mechanism for gel formation with calcium ions is known as ‘The egg box’. Into this backbone, there are regions where galacturonic acid is replaced by (1,2)-linked L-rhamnose. From the rhamnose residues, sidechains of various neutral sugars branch off. This type of pectin is called rhamnogalacturonan-I (RG-I). Up to every 25th galacturonic acid in the main chain is replaced with rhamnose. Some stretches consist of alternating galacturonic acid and rhamnose – “hairy regions”, others with lower density of rhamnose – “smooth regions”. The neutral sugars are mainly D-galactose, L-arabinose and D-xylose, the types and proportions of neutral sugars varying with the origin of pectin. Another structural type of pectin is rhamnogalacturonan II (RG-II), which is a less frequent complex, highly branched polysaccharide.</p>

<p>Ethyl D-thioglucuronide is a modification of an oligosaccharide, carbohydrate, complex carbohydrate or sugar. It can be synthesized by custom synthesis or by synthetic methods. The product is highly pure and monosaccharide methylated. The product can be glycosylated, polysaccharide, sugar fluorinated and saccharides click modified.</p>

<p>Methyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranoside is a custom synthesis that is fluorinated, methylated and monosaccharided. This compound has a CAS number of 97276-95-4, which indicates that this is an oligosaccharide. Methyl 4,6-O-benzylidene-2-deoxy-2-phthalimido (4,6) b D glucopyranoside is polysaccharide that is glycosylated and sugar. It is also complex carbohydrate with saccharide and carbonyl groups.</p>

<p>1,6:2,3-Dianhydro-4-O-benzyl-b-D-mannopyranose is a modification of the natural sugar D-mannopyranose. It is an oligosaccharide with a complex carbohydrate structure that has been synthesized by modifying the natural sugar. 1,6:2,3-Dianhydro-4-O-benzyl-b-D-mannopyranose is a high purity and monosaccharide that has been methylated and glycosylated to produce a polysaccharide sugar. This product can be used for many applications in the chemical industry including as a fluorination agent or as a saccharide in research or medical applications.</p>

<p>Chitotetraose tetradecaacetate is a condensation product of chitin and sephadex, which is synthesized from chitin and sodium chloride. It is an acetolysis substrate that has a sensitivity of 3.2 ug/ml in the fluorometric assay. Chitotetraose tetradecaacetate also exhibits high sensitivity to micrococcus, with a minimum inhibitory concentration (MIC) of 0.3 ug/ml.</p>