Glycosciences

P-Coumaroyl-b-D-glucose is a flavanone that belongs to the class of flavonoids. It is an intermediate in the synthesis of many other flavonoids, such as apigenin, labiatae, and rhamnetin. P-Coumaroyl-b-D-glucose has been shown to downregulate the expression of genes encoding proteins involved in the biosynthesis of proanthocyanidins and anthocyanins. This compound also induces apoptosis by binding to the mitochondria membrane and increasing reactive oxygen species production. P-Coumaroyl-b-D-glucose can be used as a marker for phenylpropanoid metabolism in plants.

L-Idaric acid is a novel anti-inflammatory agent that is a derivative of the endogenous compound d-glucuronic acid. It has been shown to have anti-inflammatory effects in animal studies as well as in human cell cultures and it has been shown to be safe for use in humans. L-Idaric acid inhibits the production of inflammatory mediators, such as prostaglandins, leukotrienes, and cytokines. L-Idaric acid also inhibits the activity of β-glucuronidase, which may be responsible for its ability to prevent the degradation of glucuronic acid derivatives.

Methyl b-L-daunosaminide HCl is a glycoconjugate that has been custom synthesized by our team. It is a complex carbohydrate that has been modified with glycosylation and methylation groups. Methyl b-L-daunosaminide HCl is an oligosaccharide that contains multiple saccharides linked together in a specific order. It is also fluorinated at the C4 position, which makes it more stable in water. Methyl b-L-daunosaminide HCl has high purity, making it suitable for use in the modification of other compounds or as a research tool for studying glycosylations.

Myo-inositol-d6 is a stable isotope of myo-inositol. It is used to monitor the biosynthesis of myo-inositol in yeast cells. Myo-inositol is a carbohydrate that has regulatory functions in yeast cells. Myo-inositol-d6 can be used as an extracellular bioassay for determining the uptake and intracellular distribution of myo-inositol in mammalian cells.

5-Thio-D-lactose is a monosaccharide that has been synthesized and modified to contain fluorine atoms. This synthetic sugar is used in the glycosylation of polysaccharides in the synthesis of complex carbohydrates. 5-Thio-D-lactose is also used for click modification and methylation reactions. 5-Thio-D-lactose can be used as a reference standard for carbohydrate analysis by gas chromatography, mass spectrometry, nuclear magnetic resonance, or infrared spectroscopy.
5-Thio-D-lactose is available at high purity (99%+) and with custom synthesis upon request.

Heparin derived dp16 saccharide ammonium salt is a synthetic oligosaccharide with a molecular weight of approximately 16,000 Da. The compound is an amine-modified heparin sulfate fragment containing 16 saccharides linked in a linear fashion. It has been used for the click modification of proteins, and as a carbohydrate receptor in glycosylation studies. Heparin derived dp16 saccharide ammonium salt can also be custom synthesized to meet specific needs. Click modification and fluorination are two modifications that have been applied to the compound for various purposes.

4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.

2-Acetonyl-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-galactopyranoside is a synthetic sugar that has been modified to contain an acetyl group at the C2 position. The synthesis of this compound is based on the modification of galactose with acetic anhydride. This product has been shown to be resistant to hydrolysis by esterases or glucuronidases and can also inhibit bacterial growth in culture. It is a monosaccharide with a CAS number of 85583-40-7. It is also used as a precursor for the synthesis of complex carbohydrates.

Tert-Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a synthetic derivative of the natural sugar nucleotide, UDP-N-acetylgalactosamine. It is a precursor for the synthesis of glycosaminoglycans, which are important components of proteoglycans and glycosaminoglycan aggregates. Tert-Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside has been modified by fluorination and methylation to provide increased stability and reactivity. This product is available in high purity with a CAS number of 262849-66-1.

Methyl b-D-thioxylopyranoside is a synthetic sugar that is used in the synthesis of saccharides and oligosaccharides. It is also used to modify saccharides, such as glucosamine, by adding methyl groups to the sugar's hydroxyl group. Methyl b-D-thioxylopyranoside can be used for glycans with high purity and high yield. This product does not contain any other substances except for water and ethanol. The chemical formula for this product is C6H8O6.

Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This decasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).

Food additive; soil suspension polymer in detergents; thickening agent

Mogroside II A2 is a fructan that is found in the fruit of the plant Glycosmis erythrorhiza, which is a member of the family Rutaceae. This compound has been shown to have immune-modulating properties and is used as an ingredient in some pharmaceutical drugs. Mogroside II A2 has also been demonstrated to have antiviral activity and may be helpful for cancer treatment. The effects of this compound on kidney fibrosis are unclear; however, it does have anti-inflammatory properties.

1-Deoxy-L-ribose is a metabolite of acetone. It is a monosaccharide that contains one less oxygen atom than its parent compound. 1-Deoxy-L-ribose is found in the urine and blood of humans and animals. In animals, it can be synthesized from glucose by the enzyme ribose 1-phosphate reductase. This reaction requires an energy source such as ATP or NADH to reduce ribose 1,5-bisphosphate to 1,4-dihydroxyacetone phosphate, which then undergoes spontaneous dehydration to form 1-deoxy-D-ribose.

1,3,4,6-Tetra-O-acetyl-2-O-nonafluorobutane-sulfonyl-b-D-mannopyranose is a fluorinated saccharide that can be custom synthesized. It is a glycosylated carbohydrate with a 1,3,4,6 tetra acetyl substitution at the 2 position of the b D mannopyranose moiety. The chemical formula for this compound is C12H28O8FS2. It has been shown to have potential as an antihyperglycemic agent and has been found to be active in tumor models.

Psicose diacetonide is a synthetic, custom-synthesized carbohydrate. It is a complex carbohydrate that is made of saccharides and has been modified to have a fluorinated monosaccharide. Psicose diacetonide is an oligosaccharide with a high purity and has been methylated and glycosylated.

4-O-Acetyl-3,6-di-O-benzyl-D-glucal is a custom synthesized compound with high purity. This product is a complex carbohydrate that can be used as a monosaccharide or sugar. It has been modified with fluorination and methylation to produce a compound that is resistant to degradation by enzymes and oxidation. The CAS number for this product is 165524-87-8.

5-Fluorouracil N-b-D-glucuronide is the major metabolite of 5-fluorouracil. It is mainly excreted in urine and bile, and has a high blood level. The glucuronide conjugate of 5-fluorouracin is hydrolyzed by beta-glucuronidase to generate 5-fluorouridine, which can be reabsorbed into the cell to form cytotoxic 5-fluoro uridine triphosphate. This process inhibits protein synthesis, leading to cell death. The half life of 5FU glucuronide is short and it needs to be constantly replaced with new doses. It has also been shown that levels of 5FU glucuronide are higher in tissues than in plasma, which may explain its inhibitory effect on tumors.