Glycosciences

1,3-α-D-mannopyranosyl trichloroacetimidate (1,3-α-DMTCA) is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. The synthesis of 1,3-α-DMTCA involves the reaction of α,β-unsaturated chloral hydrate with mannose in aqueous solution. This produces an intermediate product that undergoes glycosylation with glycosylation reagents like glycosyl chloride to yield 1,3-α-DMTCA. The chemical structure of 1,3-α-DMTCA can be modified by various reactions including methylation or click modification. 1,3 DMTCA is also available as a high purity material.
1,3 α - D - mannosyltetrahydrochlorofonuimidoksyl

1,4-Dideoxy-1,4-imino-D-xylitol HCl (DDX) is a potent inhibitor of the enzyme carboxypeptidase A2. DDX has been shown to inhibit the growth of HIV in vitro and in vivo. DDX also inhibits the production of proinflammatory cytokines and neurotrophic factors from HL60 cells. It has been shown to be a potential drug target for the treatment of infectious diseases such as alphaviruses, which produce a severe neuroinvasive disease in humans. DDX binds to dna with high affinity and specificity, but does not bind to RNA or proteins. DDX inhibits mitochondrial membrane potential by binding to ATP synthase and blocking the synthesis of ATP. DDX has also been shown to have an anti-oxidative injury effect on mitochondria, which may contribute to its inhibition of viral replication.

Methyl b-L-daunosaminide HCl is a glycoconjugate that has been custom synthesized by our team. It is a complex carbohydrate that has been modified with glycosylation and methylation groups. Methyl b-L-daunosaminide HCl is an oligosaccharide that contains multiple saccharides linked together in a specific order. It is also fluorinated at the C4 position, which makes it more stable in water. Methyl b-L-daunosaminide HCl has high purity, making it suitable for use in the modification of other compounds or as a research tool for studying glycosylations.

N-Boc-1,5-imino-D-glucitol is a complex carbohydrate that is synthesized by the N-Boc protection group. It is an oligosaccharide with a molecular weight of about 190 daltons and it can be modified at the C1 position to produce various saccharides. N-Boc-1,5-imino-D-glucitol has been shown to be effective as a glycosylation agent for protein modification and for its ability to form stable complexes with other complex carbohydrates. This compound has also been used in the synthesis of polysaccharides and as a fluorination reagent.

D-Arabino-5-hexulosonic acid is an intermediate in the pentose phosphate pathway. It is a component of the hexuronate, which is an important precursor for galactitol, 6-phosphate, and acid dehydrogenase. D-Arabino-5-hexulosonic acid is also an important intermediate in the glycolytic pathway for ATP production. The gene product has been shown to be involved in aerobic glycolysis, which is utilized by Staphylococcus aureus to produce energy from glucose fermentation. D-Arabino-5-hexulosonic acid plays a role in ion exchange and mitochondrial metabolism as well.

Glucose pentaacetate is a form of glucose that reacts with boron trifluoride etherate to produce anomers. This process can be used to synthesize the anomeric form of glucose, which is important for the biosynthesis of glycosides. Glucose pentaacetate has been shown to react with nitrate and trifluoride, forming conjugates with aluminum and chloride. The catalytic stereocontrol of this reaction allows for the production of disaccharides without hydrogen chloride or formylation.

N-Nonanoyl-N-methylglucamine is a nonionic surfactant that has been shown to be effective in the treatment of some inherited blood disorders. N-Nonanoyl-N-methylglucamine is used as a red cell membrane stabilizer and has been shown to increase the proton concentration in human serum. It also increases the transfer rate of p-nitrophenyl phosphate from erythrocytes to plasma. This drug has been found to have enzyme activity on soybean trypsin, model system, and epoxidase activity. N-Nonanoyl-N-methylglucamine has shown to be an effective protective agent against sodium citrate induced hemolysis and monoclonal antibody mediated cytotoxicity. It also shows kinetic data for protein synthesis and gene expression at different concentrations.

Please enquire for more information about 1,3-o-Dibenzyl-N-acetyl-β-D-glucosamine 4,6-diacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Anthracycline antibiotic with potent anti-tumoral activity. The compound interferes with DNA replication and RNA transcription since it intercalates between the base pairs of nucleic acids. It also inhibits the topoisomerase II, proteasome and generates free radicals, which leads to cell death of treated cells. Moreover, daunorubicin triggers apoptosis trough the stimulation of ceramide synthesis. It has been used as chemotherapy agent for the treatment of myeloid leukaemia (AML) and acute lymphocytic leukaemia (ALL).

Mirabegron is a drug that is used to treat overactive bladder. Mirabegron N-glucuronide is the major metabolite of mirabegron, which has been shown to be excreted in urine. This metabolite can be detected using a validated assay and can be measured using a mass spectrometer. The concentration of mirabegron N-glucuronide in the blood sample was measured at various timepoints after administration of mirabegron. Pharmacokinetic studies were performed in humans and human liver tissue, giving information on how long it takes for the drug to reach its maximum concentration in the body and how long it stays there before being eliminated.

Olmesartan acid O-b-D-glucuronide is a synthetic, high purity, and custom synthesis oligosaccharide. It can be fluorinated in the presence of a base to give a fluorinated compound with the following CAS number: 369395-57-3. Olmesartan acid O-b-D-glucuronide is an oligosaccharide that has been modified by click chemistry. This modification results in a polysaccharide that contains saccharides connected through ether linkages. The saccharides are made up of monosaccharides and disaccharides, which are all sugars.

1,3:1,4 b-Glucotriose (A) is a custom synthesis that is available with a purity of ≥98%. It is a fluorinated polysaccharide with a complex structure that can be modified to produce different variations. The methylation status of the compound can be customized as well. This product is an oligosaccharide and polysaccharide sugar that contains one glucose unit. It has been synthesized from the monosaccharide sugar and it can be used for chemical modification or for research purposes.

A disaccharide

D-Allose is a sugar that is modified with a fluorine atom at position 6. This modification can be used to trace the origin of D-allose in complex carbohydrates such as glycogen and glycosylated proteins. The addition of a 13C6 atom allows for the identification of this sugar through mass spectrometry and nuclear magnetic resonance (NMR) analysis.

3'-N-Glycolylneuraminyl-D-lactose sodium salt is a carbohydrate that has been modified by the addition of glycosylation, methylation and fluorination. It belongs to the group of complex carbohydrates and is a monosaccharide. 3'-N-Glycolylneuraminyl-D-lactose sodium salt can be used for the synthesis of oligosaccharides and polysaccharides, such as cellulose, chitin and glycogen. This product is high purity, custom synthesis and synthetic.

1-Deoxy-L-ribose is a metabolite of acetone. It is a monosaccharide that contains one less oxygen atom than its parent compound. 1-Deoxy-L-ribose is found in the urine and blood of humans and animals. In animals, it can be synthesized from glucose by the enzyme ribose 1-phosphate reductase. This reaction requires an energy source such as ATP or NADH to reduce ribose 1,5-bisphosphate to 1,4-dihydroxyacetone phosphate, which then undergoes spontaneous dehydration to form 1-deoxy-D-ribose.

Cellobiuronic acid is a polysaccharide that contains glucose and uronic acids. It is found in the cell walls of gram-positive bacteria, where it may play an important role in maintaining the structural integrity of the cell wall. Cellobiuronic acid has been shown to be a potent antigen for pneumococcus. Cellobiuronic acid has also been shown to be conjugated with proteins and used as a vaccine adjuvant for inducing antibody responses against pneumococcal antigens. Cellobiuronic acid is synthesized from glucose by bacterial cells, which use it as a carbon source. The biosynthesis of cellobiuronic acid is poorly understood because it does not occur in mammalian cells.

Psicose diacetonide is a synthetic, custom-synthesized carbohydrate. It is a complex carbohydrate that is made of saccharides and has been modified to have a fluorinated monosaccharide. Psicose diacetonide is an oligosaccharide with a high purity and has been methylated and glycosylated.