Glycosciences

Di-a-D-galactosyl-mannopentaose is a mannopentaose derivative that has been modified with a methyl group at the C2 position and fluorinated at the C6 position. This compound can be used as an intermediate in the production of oligosaccharides and polysaccharides, which are complex carbohydrates that contain many sugar molecules. The product is of high purity, with no detectable impurities. It was synthesized using a custom synthesis approach, which allows for modification of the chemical structure to produce desired properties. This product is stable when stored at room temperature and does not require refrigeration. It does not contain any organic solvents or volatile compounds and is free from endotoxins or heavy metals.

D-Arabino-5-hexulosonic acid is an intermediate in the pentose phosphate pathway. It is a component of the hexuronate, which is an important precursor for galactitol, 6-phosphate, and acid dehydrogenase. D-Arabino-5-hexulosonic acid is also an important intermediate in the glycolytic pathway for ATP production. The gene product has been shown to be involved in aerobic glycolysis, which is utilized by Staphylococcus aureus to produce energy from glucose fermentation. D-Arabino-5-hexulosonic acid plays a role in ion exchange and mitochondrial metabolism as well.

1,2,3,6-Tetra-O-benzoyl-5-thio-D-glucopyranose is a monosaccharide that can be synthesized by the methylation of 1,2,3,6-tetra-O-(benzoyl) D-glucopyranose. The synthesis of this compound is accomplished by a click modification and the use of a fluoroquinolone to modify the sugar at C1. This compound has been shown to be an excellent substrate for polysaccharide and saccharide synthesis as well as fluorination. Purity levels are high with this product.

3-O-Triisopropylsilyl-D-glucal is a modified carbohydrate, which is a saccharide that has been modified by the addition of three isopropyl groups. This modification can be used to synthesize oligosaccharides and polysaccharides in order to obtain desired properties. 3-O-Triisopropylsilyl-D-glucal can also be used as a fluorinating agent in synthesis reactions. The compound is also custom synthesized and can be synthesized with high purity (>98%) or with methylation or glycosylation. 3-O-Triisopropylsilyl-D-glucal will react with nucleophiles like amines and alcohols to form adducts, which are then hydrolyzed to release the product.

2-Hydroxyimipramine b-D-glucuronide is a custom synthesis, modification, and fluorination of the drug 2-hydroxyimipramine. The methyl group from the molecule is replaced with a fluoro group. This modification leads to a new compound with improved pharmacokinetic properties. The new compound also has glycosylation sites on the sugar ring that are not present in the parent drug. This modification may lead to an increase in the therapeutic efficacy of 2-hydroxyimipramine b-D-glucuronide as it interacts with other drugs and increases their bioavailability.

3-Amino-2,3-dideoxy-D-myo-inositol (3ADMI) is a gene product that belongs to the class of chemical biology. It is an actuator that has been shown to be able to bind and activate enzymes. 3ADMI is used as a substrate in the calibration of enzyme kinetics and as an analog for aminoglycosides. The conjugates of 3ADMI have been shown to prevent viral replication by inhibiting the synthesis of DNA or RNA.

N-Nonanoyl-N-methylglucamine is a nonionic surfactant that has been shown to be effective in the treatment of some inherited blood disorders. N-Nonanoyl-N-methylglucamine is used as a red cell membrane stabilizer and has been shown to increase the proton concentration in human serum. It also increases the transfer rate of p-nitrophenyl phosphate from erythrocytes to plasma. This drug has been found to have enzyme activity on soybean trypsin, model system, and epoxidase activity. N-Nonanoyl-N-methylglucamine has shown to be an effective protective agent against sodium citrate induced hemolysis and monoclonal antibody mediated cytotoxicity. It also shows kinetic data for protein synthesis and gene expression at different concentrations.

Glcnacβ(1-2)man-α-ethylazide is a modified oligosaccharide that has been synthesized from the sugar GlcNAcβ(1-2)mannose. It is a complex carbohydrate with a high purity, which can be used as a custom synthesis. The synthesis of this product involves fluorination and saccharide methylation. The CAS number for this product is 1858224-15-3.

3-Deoxy-3-fluoro-D-fructose is a monosaccharide that has been used as an inhibitor of glucose uptake and metabolism in the lymphocytic leukemia cell line. This compound has been shown to inhibit the glucose transporter GLUT1, which is responsible for the transport of glucose across the plasma membrane. 3-Deoxy-3-fluoro-D-fructose inhibits cancer cells by inhibiting galactitol production through inhibition of gluconeogenesis. It also inhibits oxidative phosphorylation in lymphocytic leukemia cells, leading to apoptosis. 3-Deoxy-3-fluoro-D-fructose has been shown to inhibit cancer growth by blocking glucose uptake in xenopus oocytes.

Ethyl 2,3,4-tri-O-acetyl-a-L-rhamnopyranoside is a custom synthesis of methylated oligosaccharides. It is an acetylated form of L-rhamnopyranoside that is obtained by the reaction of dl-glyceraldehyde with acetone and acetic acid. The product has been fluorinated to give a complex carbohydrate with high purity.

4-Deoxy-D-chitobiose heptaacetate is a synthetic compound that has been modified by the addition of a heptaacetate group. This modification provides an additional site for attachment to other molecules, such as nucleic acids or proteins. The fluorination of this saccharide provides further protection against degradation and increases its stability in aqueous solutions. 4-Deoxy-D-chitobiose heptaacetate is available in high purity and can be custom synthesized to meet your needs.

Propylthiouracil N-b-D-glucuronide is a glycosylation product of propylthiouracil, which is the active form of this drug. It has been shown to inhibit thyroid hormone synthesis by binding to the enzyme thyroid peroxidase. Propylthiouracil N-b-D-glucuronide is used in the treatment of thyrotoxicosis, and can also be used as an antithyroid agent for hyperthyroidism. It is chemically synthesized from propylthiouracil with a glycosyl group added at the C3 position on the thiourea ring by glycosyltransferases. This compound has also been fluorinated and polysaccharided, modified and saccharided, oligosaccharided or sugar, synthetic or monosaccharide, custom synthesis or high purity.

2,3,5-Tri-O-p-chlorobenzyl-L-fucopyranoside is a modified sugar and an effective inhibitor of the glycosidase enzymes. It has been shown to inhibit the synthesis of glycogen in vitro. 2,3,5-Tri-O-p-chlorobenzyl-L-fucopyranoside is a major component of commercially available agarose gel electrophoresis buffers and is also used for modification of proteins by click chemistry. The compound can be custom synthesised with a high degree of purity and can be fluorinated for use in mass spectrometry.

3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9

Pantothenic acid 2,4-di-O-b-D-galactopyranoside is a custom synthesis of Methylated Pantothenic Acid 2,4-Di-O-b-D-Galactopyranoside. The compound is an oligosaccharide composed of two glucose molecules and one galactose molecule. It contains a fluorine atom at the 4th position of the sugar chain. This modification was made to increase the solubility in water. Pantothenic acid 2,4-di-O-b-D-galactopyranoside can be used in industry as a food additive or pharmaceutical intermediate.

Gal[2346Ac]b(1-3)GlcN3[46Bzd]-b-MP is a custom synthesis that has been modified with fluorination, methylation, and modification. The product contains a monosaccharide, oligosaccharide, saccharides, and complex carbohydrates.

Phenyl 6-deoxy-6-fluoro-a-D-glucopyranoside is a modification of the natural sugar, deoxyglucose. It is an oligosaccharide with a complex carbohydrate structure that has been modified by methylation and glycosylation. This product is synthesized from monosaccharides, and it can be fluorinated or saccharided. Phenyl 6-deoxy-6-fluoro-a-D-glucopyranoside is used in the synthesis of polysaccharides.

Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).

2,4-O-Ethylidene-D-erythrose is a trimerization product of glyoxal and acetaldehyde. It is an aldehyde that can be used as a precursor to other compounds. The hydrated form of 2,4-O-ethylidene-D-erythrose has been rationalized by the mesoxalic acid and water molecules to form the trimer. This compound can be produced from the glycolaldehyde and sulfoxide in an oxidation reaction with hydrogen peroxide. The acetylation of 2,4-O-ethylidene-D-erythrose produces isoxazolidines which are stereoselective.

Hexyl b-D-thioglucopyranoside is an insect pheromone that attracts male mealworms. It can be used for the detection of chiral elements, such as carbon and hydrogen. The profile of hexyl b-D-thioglucopyranoside is dynamically programmable and can be modified to detect different types of insects by changing the carbon skeleton. Hexyl b-D-thioglucopyranoside has been shown to have a strong electromagnetic activity, which may be due to its carbon skeleton.

This compound is a modification of the 2-bromoethyl a-L-fucopyranoside. It is an oligosaccharide that is a carbohydrate. It is made up of many monosaccharides, which are sugar molecules linked together. This modified carbohydrate has been synthesized from other carbohydrates and then fluorinated to make it more stable.

4,6-O-Benzylidene-a-D-galactopyranoside is an artificial sweetener that has a high purity and can be custom synthesized. This compound is also known as an oligosaccharide or complex carbohydrate. It is a member of the saccharide family, which includes monosaccharides and disaccharides. 4,6-O-Benzylidene-a-D-galactopyranoside is a sugar that has been modified by glycosylation and methylation. This product has CAS No. 57783-86-5 and can be found in the Glycosides section of the Chemical Directory.

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Mirabegron is a drug that is used to treat overactive bladder. Mirabegron N-glucuronide is the major metabolite of mirabegron, which has been shown to be excreted in urine. This metabolite can be detected using a validated assay and can be measured using a mass spectrometer. The concentration of mirabegron N-glucuronide in the blood sample was measured at various timepoints after administration of mirabegron. Pharmacokinetic studies were performed in humans and human liver tissue, giving information on how long it takes for the drug to reach its maximum concentration in the body and how long it stays there before being eliminated.

4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.

Fucose 2-nitrophenylhydrazone is a custom synthesis that is a modification of fucose. It has been used in methylation, click modification, and fluorination. This compound has been shown to be effective in the synthesis of oligosaccharides and polysaccharides. Fucose 2-nitrophenylhydrazone has also been used as an intermediate for the synthesis of saccharides such as monosaccharide and sugar.

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-galactopyranoside is a custom synthesis that belongs to the class of complex carbohydrates. This compound is an oligosaccharide or a polysaccharide that has been modified by methylation and glycosylation. The modification of this saccharide with methyl groups allows for fluorination which is a click modification. Methyl 2,3-di-O-benzoyl-4,6-O-benzylidene b -D galactopyranoside is synthesized via glycosylation followed by fluorination. This product can be used as a research chemical or in other applications.

Ramipril acyl-b-D-glucuronide is a glycosylated prodrug that is the active form of ramipril, an ACE inhibitor. It is metabolized in the liver to ramipril and excreted in the urine. Ramipril acyl-b-D-glucuronide has been shown to have an increased bioavailability and a longer half-life than ramipril due to its glycosylation. The synthesis of this drug has been modified by methylation, fluorination, and saccharide modification. This compound is also available as a custom synthesis for research purposes with high purity.

D-glucose 6-phosphate is an intermediate in the hexose monophosphate shunt pathway. It is formed by the enzyme phosphoglucomutase from D-glucose 1-phosphate and UTP. D-glucose 6-phosphate is also an important intermediate in glycolysis. The conversion of D-glucose 6-phosphate to glucose 1,6-bisphosphate occurs through a series of reactions catalyzed by enzymes that are sensitive to inhibition by magnesium ions. These reactions include the phosphofructokinase, hexokinase, and pyruvate kinase reactions. The accumulation of glucose 6-phosphate leads to increased levels of lactate production and decreased levels of ATP production. This may be due to its ability to inhibit monoamine reuptake, which would lead to decreased synthesis of dopamine and serotonin.

Raltegravir b-D-glucuronide is a synthetic, fluorinated analog of raltegravir. It is a potent HIV-1 integrase inhibitor that has been shown to be active against the majority of HIV-1 strains. Raltegravir b-D-glucuronide is less potent than the parent compound and exhibits reduced antiviral activity in vitro. Raltegravir b-D-glucuronide is metabolized to raltegravir and eliminated in urine as the glucuronide conjugate.

2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-galactopyranose is a fluorinated complex carbohydrate that has been modified by methylation and acetylation. This product is a custom synthesis that has not been previously described in the scientific literature. It is synthesized from 2, 3, 4, 6 tetraacetyl alpha D galactopyranoside and 2 deoxy alpha D galactopyranose. The chemical properties of this compound are similar to those of other complex carbohydrates such as glycogen and heparin.

This chemical is a custom synthesis of (-)-Lyoniresinol 9'-O-glucoside. The chemical is a modification of (-)-Lyoniresinol 9'-O-glucoside and fluorinated at the C2 position. It is also methylated on the C3 position. The chemical is synthesized by click chemistry, which involves the use of copper(II) ions as catalysts to generate covalent bonds between two molecules. This chemical has been shown to be an oligosaccharide with saccharide chains that are linked together by glycosylation. There are six sugar residues in this compound: glucose, galactose, rhamnose, xylose, glucuronic acid, and mannitol. This compound has CAS number 143236-02-6 and molecular weight of 881.5 g/mol (CAS No.).

Clofibric acid acyl-b-D-glucuronide is a reactive chemical species that has been shown to have genotoxic effects. It binds to DNA and forms covalent adducts, leading to mutations in the DNA sequence. Clofibric acid acyl-b-D-glucuronide is a metabolite of clofibrate, which is used for the treatment of hyperlipidemia and atherosclerosis. This metabolite can be detected in human blood, serum, and liver samples by GC/MS, with a limit of detection of 0.1 ng/mL (0.0003 µg/L).

6-O-Trityl-D-glucose is a sugar derivative that is synthesized by reacting 6,6'-dichloro-1,1'-binaphthyl with D-glucose. It has been used as a model for the stereospecific hydrolysis of polystyrene catalyzed by lipase. The reactive carbonyl group in the molecule allows for substitution reactions to occur at the hydroxyl groups and yields are dependent on the substituent effects.

(2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-2-hydroxymethyl-7,9-diaza-1-oxa-spiro[4,5]decane-10-one-8-thione is a custom synthesis of a polysaccharide. It has been modified to include fluorination and methylation. The monosaccharides present are glucose and galactose. This polysaccharide also has a saccharide linkage to an oligosaccharide that contains glycosylation sites for sugar groups.

Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This decasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).

Allyl 4,6-O-benzylidene-b-L-glucopyranoside is a carbohydrate that is synthesized from allyl alcohol and glucose. It is a complex carbohydrate made up of two different saccharides. This product can be custom synthesized to meet your needs. Allyl 4,6-O-benzylidene-b-L-glucopyranoside has been modified by fluorination, methylation and glycosylation. It has the CAS number 133394-02-0 and can be synthesized at high purity levels.

Heparin derived dp20 saccharide ammonium salt is a synthetic, high purity, complex carbohydrate that has been modified with fluorination and methylation. It is a polysaccharide composed of repeating units of D-glucosamine and D-mannose, which are linked by alternating alpha 1-6 and alpha 1-4 glycosidic bonds. This product can be used as a monosaccharide or sugar in the synthesis of oligosaccharides or polysaccharides.

5-Thio-D-lactose is a monosaccharide that has been synthesized and modified to contain fluorine atoms. This synthetic sugar is used in the glycosylation of polysaccharides in the synthesis of complex carbohydrates. 5-Thio-D-lactose is also used for click modification and methylation reactions. 5-Thio-D-lactose can be used as a reference standard for carbohydrate analysis by gas chromatography, mass spectrometry, nuclear magnetic resonance, or infrared spectroscopy.
5-Thio-D-lactose is available at high purity (99%+) and with custom synthesis upon request.

1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-ribofuranose is a custom synthesis. It is a complex carbohydrate that has been modified by methylation and glycosylation. This molecule has been fluorinated to produce a high purity product with the desired properties. The 1,2-O-isopropylidene group provides for increased stability and solubility of the product.

Heptadecyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a solubilized ion pair that can be catalysed by amines and immobilized lipase. It is also a hydrophobic fatty acid ester. Heptadecyl 2-acetamido-2-deoxy-b-D-glucopyranoside is catalyzed by an enzyme, lipase, to form the corresponding amide. This reaction yield is increased in the presence of hexane, which aids in hydrolysis of the ester linkage between heptadecyl and 2,2′-diacetylidenebis(3,4,6,-trimethylphenol). Heptadecyl 2-acetamido-2-deoxyglucopyranoside is used as a substrate for lipases to produce amides from amines. This product has been used in the production of

Psicose diacetonide is a synthetic, custom-synthesized carbohydrate. It is a complex carbohydrate that is made of saccharides and has been modified to have a fluorinated monosaccharide. Psicose diacetonide is an oligosaccharide with a high purity and has been methylated and glycosylated.

3-Pyridinylmethylbeta-D-glucopyranoside is a sugar that can be custom synthesized. It is a white to off-white crystalline powder with an odorless taste and is soluble in water. 3-Pyridinylmethylbeta-D-glucopyranoside is used in the synthesis of glycosides, saccharides, oligosaccharides, and monosaccharides. This compound can also be modified with fluorination or methylation reactions. The use of this product has been shown to produce high purity compounds for use in pharmaceuticals, agrochemicals, and other chemical industries.