Glycosciences

<p>1-Deoxythiomannojirimycin is a potent inhibitor of glycosidases, including α-amylase, β-glucanase, and α-glucosidase. This compound has been synthesized from thiomannose and jirimycin. Thiomannose is a natural compound that can be found in almond extract or as a byproduct of the hydrolysis of mannitol during hydrogenation. It can also be produced enzymatically from glucose by using β-mannosidase or α-mannosidase. 1-Deoxythiomannojirimycin inhibits the activity of glycosidases by forming an irreversible covalent bond with the active site serine hydroxyl group on the enzyme. This inhibits the cleavage of substrates such as starch into reducing sugars (e.g., glucose) and disaccharides (e.g., maltose).</p>

<p>2-Azido-2-deoxy-3,4-(R)-benzylidene-D-arabino-1.5-lactone is a fluorinated sugar that can be used for glycosylation reactions. It is a custom synthesis and its CAS number is 54856-82-9. This sugar has been modified with methyl groups to increase its stability in the presence of water. The sugar is highly pure and has a purity of 98%.</p>

<p>k-carrageenan derived tetrasaccharide alcohol disulfate+(3-6 anhydrogalactose)</p>

<p>2,3,5,6-Tetra-O-acetyl-D-galactono-1,4-lactone is a morpholidate that can be synthesized from l-fucose and phosphates. This chemical has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis. The compound also inhibits the production of diphosphorylated guanosine (GDP) from guanosine monophosphate (GMP), which may be important in the regulation of cellular growth. 2,3,5,6-Tetra-O-acetyl-D-galactono-1,4-lactone has also been shown to inhibit the conversion of GMP into GTP by binding to the enzyme GMP synthase.</p>

<p>Maltoeicosaose is a synthetic oligosaccharide that is synthesized by the glycosylation of maltose with a sugar. Maltoeicosaose can be custom synthesized for different applications, such as complex carbohydrate, glycosylation, polysaccharide, and click modification.</p>

<p>7, 8, 9, 10-Tetradeoxy-1,2:5,6-O-isopropylidene-L-glycero-a-D-gluco--decofuranose is a custom synthesis of a monosaccharide that can be modified with fluorination or methylation. It is synthesized by the click modification of an oligosaccharide and saccharide. This compound has CAS No. 156637-10-3 and is classified as a polysaccharide. 7,8,9,10 Tetradeoxy 1,2:5,6 O Isopropylidene L Glycero A D Glucodecofuranose is a carbohydrate that has glycosylation and sugar modifications.</p>

<p>4-O-Acetyl-N-acetyl-neuraminic acid is a derivative of sialic acid, which is an important component of the human cell membrane. It has been found to have inhibitory properties against influenza virus and other viruses. 4-O-Acetyl-N-acetyl-neuraminic acid inhibits viral activity by irreversible inhibition of the α subunit on the surface glycoprotein, preventing it from binding to host cells. This compound has been shown to be effective against hepatitis B virus and galleria mellonella (a type of wax moth). 4-O-Acetylneuraminic acid has also been shown to be effective in inhibiting the replication of Influenza A virus strains that are resistant to neuraminidase inhibitors such as zanamivir and oseltamivir.</p>

<p>Promotes hyaluronic acid production; synthetic building block</p>

<p>Scyllo-inosamine is a redox potential that belongs to the class of antimicrobial agents. It is derived from the amino acid inosine, which is found in RNA and DNA. Scyllo-inosamine has been shown to inhibit bacterial growth by inhibiting protein synthesis. It also acts as an aminotransferase inhibitor, which may be used for the treatment of certain human pathogens. Scyllo-inosamine has been shown to have beneficial effects on the regulation of benzyl groups and hydroxyl group reactions. It has also been shown to inhibit polymerase chain reaction activity and titration calorimetry activity.</p>

<p>(S)-3-((2R,3S,5S)-5-Allyl-3-(benzyloxy)-4-oxotetrahydrofuran-2-yl)propane-1,2-diyl dibenzoate is a small molecule that inhibits the activity of the epidermal growth factor receptor (EGFR). The EGFR is a transmembrane protein that binds to and signals through growth factor proteins. Inhibition of EGFR signaling prevents activation of downstream proteins such as extracellular signal regulated kinase 1/2 and phosphatidylinositol 3 kinase. This stabilized form has been shown to inhibit the growth of tumor cells in vitro and in vivo.</p>

<p>N-Methyl-L-glucosamine is a monosaccharide that is used as a building block for glycosaminoglycans. It can be synthesized by the enzyme glucoamylase from glucose and UDP-N-acetylglucosamine, or supplied exogenously as a dietary supplement. N-Methyl-L-glucosamine is stable in the presence of light and resistant to microbial degradation. This agent has been shown to be effective in inhibiting skin cancer in mice when combined with other agents such as hydroquinone, retinoic acid, and tretinoin. N-Methyl-L-glucosamine has been shown to have antiangiogenic properties on tubule cells, which may be due to its ability to inhibit the production of vascular endothelial growth factor (VEGF) in these cells.</p>

<p>Methyl 2,4-di-O-methyl-α-D-galactopyranoside is a synthetic saccharide that has been modified with methyl groups at the C2 and C4 positions.</p>

<p>Allyl 3,4-di-O-benzyl-2-O-(2-naphthylmethyl)-a-D-galactopyranoside is a synthetic carbohydrate with a complex structure. It is a modification of a D-galactopyranose sugar and has been glycosylated and methylated. This compound contains an allyl group that has been fluorinated at the 3 position.</p>

<p>Obtained by the partial acetolysis of lambda-carrageenan</p>

<p>2, 4-Anhydro-5-O-tert.butyldimethylsilyl-6-deoxy-L-mannonic acid methyl ester is a modification of mannose. It is an oligosaccharide with a complex carbohydrate structure. 2, 4-Anhydro-5-O-tert.butyldimethylsilyl-6-deoxy-L-mannonic acid methyl ester has been synthesized using custom synthesis methods. This product has high purity and CAS number: 29674–84–3.</p>

<p>1,3-Diazido-1,2,3-trideoxy-4-O-(2,6-diazido-2,6-dideoxy-a-D-glucopyranosyl)-D-myo--inositol is a synthetic sugar that is used for glycosylation. It can be modified with fluorine to produce a fluorinated sugar. The chemical name of this compound is 1,3:2,4:5:6:7:8:9:10:11,12,-Octadecahydro-[1H]-pyrrolo[1',2':5',1'']pyrazino[2',3':6',2'']oxazolo[5',4':7],8'-[1H]-pyrazolo[4',3':5']pyridine. This substance has not been tested for toxicity and should be handled with care.</p>

<p>2-Azido-2-deoxy-L-xylonic acid is a synthetic monosaccharide and a member of the xylonic acid family. It is used in the synthesis of glycosides and oligosaccharides, as well as being used to modify proteins. 2-Azido-2-deoxy-L-xylonic acid has been fluorinated and then glycosylated with a variety of saccharides including maltose, cellobiose, and sucrose. This compound is also methylated at the hydroxyl group to give an azidomethyl ester derivative. The chemical name for this compound is 2-[(2S)-2-(diethylamino)ethylamino]pentanedioic acid, 2-[1-(diethylamino)ethyl]azide].</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-mannopyranosyl)-D-glucopyranose (MDP) is a complex carbohydrate that has been modified by methylation, glycosylation, and carbocation. MDP is a saccharide that can be used in the synthesis of polysaccharides or as an intermediate for other chemical syntheses. It is also possible to modify MDP with fluorination, which may be useful in the synthesis of new types of pharmaceuticals.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ecklonia (illustrated), Alaria and Cladosiphon) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content of this fucan is approx. 19.0% and it also contains galactose (approx. 12.0%), uronic acid (approx. 25.5%) and sulfate (approx. 19.1%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Lactose 6'-sulfate is a custom synthesis of a complex carbohydrate and an oligosaccharide. It is modified by methylation and glycosylation, which can be altered to create other saccharides such as galactose. Lactose 6'-sulfate has been fluorinated in the alpha position and contains a sulfate group that is attached with a click chemistry reaction. Lactose 6'-sulfate has CAS number 1015758-24-3 and is high purity.</p>

<p>3'-Sialyl Lewis X 1-N-methyl-N-hydroxyethylamine is a custom synthesis of a monosaccharide that contains an N-hydroxymethyl group. The fluorination and methylation reactions are examples of modifications that can be done to this molecule. This monosaccharide can be modified by the click chemistry reaction, which involves the use of azide and alkyne reagents. 3'-Sialyl Lewis X 1-N-methyl-N-hydroxyethylamine is used in glycosylation with complex carbohydrates such as polysaccharides and saccharides, which are large sugars or sugar chains.</p>

<p>The synthesis of 1,2-ethanediol is accomplished by the reaction of benzaldehyde with ethanol. This product is a synthetic sugar that is used in the modification of polysaccharides and glycosylation. The molecular weight of this product ranges from 200 to 400 Daltons. It has a CAS number of 730-25-6.</p>

<p>Ixoroside is a coumarin derivative that has been shown to inhibit the activity of an enzyme called epidermal growth factor receptor. The chemical diversity of this compound has made it difficult to study its biological properties and mechanisms. Ixoroside has been studied in vitro for its effects on eye disorders and for its potential to be used as a monoclonal antibody. It has also been shown to have toxicological studies with no significant adverse effects observed. Ixoroside is found in the genus Nepeta, where it is mainly found in Nepeta cataria and Fructus ixorii species plants, which are used in traditional Chinese medicine. It can also be found in other plants such as Eucalyptus globulus, which is commonly used in cough suppressants.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>(1R,2S,3S,5R)-5-Benzyloxy-3-(tert-butyldimethylsilyloxy)-2-hydroxymethyl cyclohexanol is a fluorinated carbohydrate that has been synthesized by a monosaccharide and oligosaccharide. This compound is a complex carbohydrate that has been glycosylated, methylated and modified with click chemistry. This product is available in high purity with CAS number.</p>

<p>3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a Custom synthesis of the monosaccharide galactose. It is modified with fluorine at the 3 and 4 positions on the carbon chain and also has an acetyl group at the 6 position. 3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is synthesized from the sugar glucose by methylation of the hydroxyl groups on C1 and C2. The chemical formula for this compound is C8H14N2O5. This molecule has a molecular weight of 204.22 g/mol and its CAS number is 819053-49-1.</p>

<p>The fluorescence intensity of these Rhodamine B isothiocyanate-dextrans varies much less than with FITC-dextrans.</p>

<p>D-Altro-Amide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide. The synthesis of D-Altro-Amide is done through modification, click modification, and oligosaccharides. It's CAS number is 69092-57-5. D-Altro-Amide is a polysaccharide made from glycosylation and sugar. Carbohydrates are complex carbohydrates with many saccharides connected together in an ordered manner.</p>

<p>The 1,2,3,4-Tetra-O-benzoyl-6-O-triisopropylsilyl-a-D-mannopyranose is a high purity custom synthesis sugar. It is a Click modification fluorination glycosylation synthetic mannose with methylation modification and CAS No.<br>Mannosaccharide is an oligosaccharide that consists of three monosaccharides linked by alpha (1-&gt;4) bonds. Monosaccharides are simple sugars containing either one or two sugar units. Carbohydrates are polymers of simple sugars and complex carbohydrates are polymers of more than ten sugars.</p>

<p>(2R, 3S, 4R) -3-Acetyloxy - 4-azido-1-benzyl-2-pyrrolidinemethanol 2-acetate is a fluorinated monosaccharide that exhibits high purity and custom synthesis. It is used in the production of oligosaccharides, polysaccharides, and complex carbohydrates. The CAS number for this product is 53795-42-3.</p>

<p>Intermediate for synthesis of N-acetyllactosaminic glycans</p>

<p>2-C- (Hydroxymethyl) -2, 3:5, 6-di-O-isopropylidene-D-mannose is an Oligosaccharide. It is a water soluble polysaccharide that is found in the cell walls of certain bacteria. The synthesis of this compound can be achieved through Click modification and fluorination. This product has a CAS number and can be custom synthesized to meet your needs.</p>

<p>Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a carbohydrate that has been modified with fluorination. It is synthesized by the methylation of glucose and mannose residues, followed by glycosylation. Methyl 6-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a custom synthesis and can be ordered in high purity.</p>

<p>D-Mannosaminuronic acid is a monosaccharide that has been isolated from the seed of the African plant, Acacia drepanolobium. It is found to be an antigenic component of shigella and related enterobacteria and plays an important role in the biosynthesis of glycolipids. D-Mannosaminuronic acid can be hydrolyzed by acidic enzymes such as lipases, esterases, phosphatases, or proteases. This process may lead to the liberation of fatty acids and sugars. The purified enzyme preparations have been shown to catalyze the synthesis of D-mannosaminuronic acid from mannose and fructose.</p>

<p>D-myo-inositol 3-phosphate (IP3) is a molecule that is involved in the metabolism of carbohydrates, fats, and proteins. It is synthesized from D-myo-inositol 1,4,5-trisphosphate through the action of an enzyme called phosphatidylinositol kinase. IP3 binds to the calmodulin protein and has been shown to have biological properties, such as cytosolic or chloroplastic localization and transcriptional regulation. IP3 also participates in the synthesis of DNA and RNA. The sequence of IP3 has been determined for plants such as Solanum tuberosum and Arabidopsis thaliana.</p>

<p>Propargyl a-D-galactopyranoside (PGAL) is a synthetic compound that belongs to the group of oligosaccharides. PGAL can be used in the synthesis of glycosylated saccharides, such as glycoproteins and glycolipids. The modification of PGAL with fluorine atoms is known to increase its stability. It has been shown that PGAL can be modified with methyl groups without affecting its chemical properties. Furthermore, PGAL can be modified with click chemistry reactions, which are chemoselective reactions that are catalyzed by copper(I) ions.</p>

<p>Please enquire for more information about 2-O-(a-D-Galactopyranosyl)-a-L-fucopyranosyl propylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is a modification of the natural sugar N-acetylneuraminic acid. It can be synthesized by reacting 1,2,3-¹³C3]cytidine with sodium hydroxide and acetic anhydride in methanol. It is a carbohydrate that can be found in many plants and animals. This compound has been shown to inhibit glycosylation and methylation reactions. N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is also a monosaccharide that belongs to the group of sugars. Due to its high purity and availability, this substance can be used as a substitute for sialic acid in research experiments.</p>

<p>This compound has been used in the study of cellulase kinetics</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>4-Aminophenyl a-D-mannopyranoside is a compound that has been shown to have anti-inflammatory properties. It is also used as a starting material in the synthesis of other drugs. Rats with chronic kidney disease were given 4-aminophenyl a-D-mannopyranoside daily for three weeks, and it was found that this compound prevented the development of kidney injury markers. This drug has also been shown to be effective against mouse strains with nervous system diseases. 4-Aminophenyl a-D-mannopyranoside binds to lysine residues on proteins and prevents the interactions between these residues and the amino acid glutathione, which is required for glut1 uptake in brain cells. This uptake is essential for cellular function, and therefore 4-aminophenyl a-D-mannopyranoside may be useful as chemotherapeutic treatment for brain cancer.</p>

<p>This is a custom synthesis of a carbohydrate. It is a methylated, glycosylated, fluorinated, complex carbohydrate that can be synthesized to any desired degree of substitution. This product has been designed for use as a fluorescent tag or label in biochemistry and cell biology research. It is modified at the anomeric position with an acetyl group and an azide group. The acetyl group confers solubility in water, while the azide group confers fluorescence. The modifications also allow for click chemistry reactions, which are used in protein labeling and activation studies.</p>

<p>Chitotriose trihydrochloride is a modification of chitin, an oligosaccharide. Chitotriose trihydrochloride is a synthetic carbohydrate which is used as a raw material for the production of fibers, films, and adhesives. It can be used in the synthesis of complex carbohydrates such as starch and glycogen. Chitotriose trihydrochloride is a high purity carbohydrate with CAS No. 41708-93-4 that can be used to produce glycosylated proteins or polysaccharides.</p>

<p>4-O-Acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl trichloroacetimidate is a methylated saccharide that can be obtained through the Click modification of an oligosaccharide. It is a custom synthesis that has been modified with fluorination. This product is available in high purity and has been glycosylated. It is also a synthetic carbohydrate with a complex structure.</p>

<p>(3S,4R) -Dihydro-3-hydroxy-3-methyl-4-tert butyldimethylsilyloxy-2(3H) -furanone is a fluorinated glycosylated monosaccharide. This compound is used as a synthetic intermediate in the custom synthesis of saccharides and oligosaccharides.</p>

<p>(1S) -1- [(2S, 3R,4R) -4-Hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that can be used as a glycosylation or click modification agent. It is also used in the synthesis of complex carbohydrates. This product has been shown to have high purity and is available for custom synthesis.</p>

<p>1-Amino-D-butane-2,3,4-triol is a custom synthesis of 1,2,3,4-1-amino butane. It has been modified with fluorination and methylation. This product has a CAS number of 20897-16-0. The molecular weight is 152.17 g/mol and the molecular formula is C6H11NO3. This product is a synthetic compound that consists of monosaccharides and oligosaccharides. The glycosylation is Oligosaccharide and saccharide. It can be found in the carbohydrate category as it contains complex carbohydrates.</p>

<p>2C-Hydroxymethyl-2,3:5,6-di-O-isopropylidene-L-gulono-1,4-lactone is a synthetic compound with the molecular formula C8H11O7. It is a sugar derivative that is used as an intermediate in the synthesis of saccharides and oligosaccharides. 2C-Hydroxymethyl-2,3:5,6-di-O-isopropylidene-L-gulono-1,4 -lactone has been shown to be a good candidate for Click chemistry modification.</p>