Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
837 produits trouvés pour "Antifongiques"
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Nikkomycin Z
CAS :<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formule :C20H25N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44ATPase-IN-5
CAS :<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Formule :C10H10N4O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :266.28A25822B
CAS :<p>A25822B is an antifungal agent.</p>Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88GW461484A
CAS :<p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>Formule :C19H14FN3Couleur et forme :SolidMasse moléculaire :303.333Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formule :C23H23N3O5Couleur et forme :SolidMasse moléculaire :421.45Succinate dehydrogenase-IN-8
CAS :<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Formule :C22H19Cl2F2N5O2Couleur et forme :SolidMasse moléculaire :494.32Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formule :C24H24N4O8Couleur et forme :SolidMasse moléculaire :496.47Wikstrol A
CAS :<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Formule :C30H22O10Couleur et forme :SolidMasse moléculaire :542.49Antifungal agent 13
CAS :<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formule :C22H20Cl2N4SeCouleur et forme :SolidMasse moléculaire :490.29Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.13CDA-IN-1
CAS :<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281SDH-IN-25
CAS :<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Formule :C19H15BrCl2N2O4Couleur et forme :SolidMasse moléculaire :486.143Furametpyr
CAS :Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formule :C17H20ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.81Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formule :C19H18F4O2Couleur et forme :SolidMasse moléculaire :354.34Tenellin
CAS :<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41CDA-IN-2
CAS :<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formule :C17H16N2O7Couleur et forme :SolidMasse moléculaire :360.318Antifungal agent 125
CAS :<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formule :C13H10BrNO4SCouleur et forme :SolidMasse moléculaire :356.192Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55Antifungal agent 39
CAS :<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Formule :C23H22ClN3O5Couleur et forme :SolidMasse moléculaire :455.89Yck2-IN-1
CAS :<p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>Formule :C19H11FN4Couleur et forme :SolidMasse moléculaire :314.316Griseofulvic Acid
CAS :<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formule :C16H15ClO6Masse moléculaire :338.74Hyalodendrin
CAS :<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formule :C14H16N2O3S2Couleur et forme :SolidMasse moléculaire :324.42Antibacterial agent 188
CAS :<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Formule :C22H20Cl2N4Se2Couleur et forme :SolidMasse moléculaire :569.25Complex III-IN-1
<p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>Formule :C14H20ClNO2S2Couleur et forme :SolidMasse moléculaire :333.9Antifungal agent 100
CAS :<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formule :C23H21N3O4SCouleur et forme :SolidMasse moléculaire :435.5bc1 Complex-IN-1
CAS :<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formule :C16H22N6O5S2Couleur et forme :SolidMasse moléculaire :442.513D75-4590
CAS :<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formule :C21H27N5Degré de pureté :98.56% - 98.85%Couleur et forme :SolidMasse moléculaire :349.474-Hydroxyvoriconazole
CAS :<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Degré de pureté :Min. 95%(S,S)-Valifenalate
CAS :<p>(S,S)-Valifenalate is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes.</p>Formule :C19H27ClN2O5Couleur et forme :SolidMasse moléculaire :398.88Tetraconazole
CAS :<p>Tetraconazole is an agent of pesticides.</p>Formule :C13H11Cl2F4N3OCouleur et forme :Liquid ViscousMasse moléculaire :372.14Rhizocticin A
CAS :<p>Rhizocticin A is a potential inhibitor of threonine synthase.</p>Formule :C11H22N5O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.3
