Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
908 produits trouvés pour "Antifongiques"
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WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47Wikstrol A
CAS :Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Formule :C30H22O10Couleur et forme :SolidMasse moléculaire :542.49Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formule :C23H22BrN3O5Couleur et forme :SolidMasse moléculaire :500.34Complex III-IN-2
Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.Formule :C15H21ClN2O2SCouleur et forme :SolidMasse moléculaire :328.86Antifungal agent 134
CAS :Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Formule :C18H12F4N2O4Couleur et forme :SolidMasse moléculaire :396.29Pyriofenone
CAS :Pyriofenone (IKF-309) is an aryl phenyl ketone fungicide predominantly used to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. It exhibits moderate efficacy against rice blast disease. Pyriofenone functions through prevention, residue activity, treatment, rainfastness, translaminar action, and fumigation.Formule :C18H20ClNO5Couleur et forme :SolidMasse moléculaire :365.81AnCDA-IN-1
CAS :AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.Formule :C16H13ClN4O2Couleur et forme :SolidMasse moléculaire :328.753Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Formule :C14H20ClNO2S2Couleur et forme :SolidMasse moléculaire :333.9Antifungal agent 13
CAS :Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83Benzohydroxamic acid
CAS :Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.136RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formule :C41H78N8O5Couleur et forme :SolidMasse moléculaire :763.11(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83CDA-IN-1
CAS :CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281Antifungal agent 127
CAS :Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.Formule :C13H12ClN3OCouleur et forme :SolidMasse moléculaire :261.707Hyalodendrin
CAS :Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.Formule :C14H16N2O3S2Couleur et forme :SolidMasse moléculaire :324.42HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Couleur et forme :SolidChitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormule :C23H23N3O5Couleur et forme :SolidMasse moléculaire :421.45Antibacterial agent 188
CAS :Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3
