Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
835 produits trouvés pour "Antifongiques"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
APX001
CAS :<p>APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.</p>Formule :C22H21N4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.4VT-1598
CAS :<p>VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.</p>Formule :C31H20F4N6O2Couleur et forme :SolidMasse moléculaire :584.52Antifungal agent 26
CAS :<p>Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1</p>Formule :C40H45N3O18Couleur et forme :SolidMasse moléculaire :855.79Loflucarban
CAS :<p>Loflucarban (Fluonilid) is an antimycotic compoud.</p>Formule :C13H9Cl2FN2SDegré de pureté :98.08% - 98.15%Couleur et forme :SolidMasse moléculaire :315.19TMV-IN-5
CAS :<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formule :C22H23N3SCouleur et forme :SolidMasse moléculaire :361.5Antifungal agent 66
CAS :<p>Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on</p>Formule :C19H25ClO6Couleur et forme :SolidMasse moléculaire :384.85Antifungal agent 48
CAS :<p>Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].</p>Formule :C13H10O4SCouleur et forme :SolidMasse moléculaire :262.28Eucalyptacid A
CAS :<p>Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)</p>Formule :C17H32O5Couleur et forme :SolidMasse moléculaire :316.43Prochloraz manganese
CAS :<p>Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.</p>Formule :C60H64Cl14MnN12O8Couleur et forme :SolidMasse moléculaire :1632.51MoTPS1-IN-1
CAS :<p>MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.</p>Formule :C23H27F3N2O4Degré de pureté :99.28%Couleur et forme :SoildMasse moléculaire :452.47Verazine
CAS :<p>(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral</p>Formule :C27H43NOCouleur et forme :SolidMasse moléculaire :397.642-Dodecanol
CAS :<p>2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].</p>Formule :C12H26OCouleur et forme :SolidMasse moléculaire :186.33Antifungal agent 49
CAS :<p>Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].</p>Formule :C15H12O4Couleur et forme :SolidMasse moléculaire :256.25APX2039
CAS :<p>APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity</p>Formule :C20H15FN4O2Degré de pureté :98.72% - 99.07%Couleur et forme :SolidMasse moléculaire :362.36Fenpropidin
CAS :<p>Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.</p>Formule :C19H31NDegré de pureté :98.58% - 99.54%Couleur et forme :SolidMasse moléculaire :273.46Y18501
CAS :<p>Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.</p>Formule :C27H26F2N6O2SCouleur et forme :SolidMasse moléculaire :536.6Dihydroaltenuene B
CAS :<p>Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.</p>Formule :C15H18O6Couleur et forme :SolidMasse moléculaire :294.3HDAC/HSP90-IN-3
CAS :<p>HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.</p>Formule :C26H33N5O6Couleur et forme :SolidMasse moléculaire :511.57Antiproliferative agent-18
CAS :<p>Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].</p>Formule :C26H27FN2OSCouleur et forme :SolidMasse moléculaire :434.57Antifungal agent 77
CAS :<p>Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, Helicoverpa</p>Formule :C21H18FN5O2Couleur et forme :SolidMasse moléculaire :391.4Chitin synthase inhibitor 14
CAS :<p>Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant</p>Formule :C25H26ClN5O5Couleur et forme :SolidMasse moléculaire :511.96Orysastrobin
CAS :<p>Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheath</p>Formule :C18H25N5O5Couleur et forme :SolidMasse moléculaire :391.42Zoxamide
CAS :<p>Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [</p>Formule :C14H16Cl3NO2Couleur et forme :SolidMasse moléculaire :336.64Inz-5
CAS :<p>Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.</p>Formule :C18H14F4N6Couleur et forme :SolidMasse moléculaire :390.34Econazole
CAS :<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Formule :C18H15Cl3N2ODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :381.68 g/molFengycin
CAS :<p>Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.</p>Formule :C72H110N12O20Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :1,463.71 g/mol2,4′-Dichloroacetanilide
CAS :<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Formule :C8H7Cl2NODegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :204.05Fosmanogepix
CAS :<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formule :C22H21N4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.40Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.41CDA-IN-4
CAS :<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formule :C10H9BrN4O2SCouleur et forme :SolidMasse moléculaire :329.17HDAC-IN-87
CAS :<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Formule :C13H7F5N4O2SCouleur et forme :SolidMasse moléculaire :378.277Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47Antifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Formule :C22H29N5OSCouleur et forme :SolidMasse moléculaire :411.56AnCDA-IN-1
CAS :<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Formule :C16H13ClN4O2Couleur et forme :SolidMasse moléculaire :328.753Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.13Antifungal agent 100
CAS :<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formule :C23H21N3O4SCouleur et forme :SolidMasse moléculaire :435.5Antibacterial agent 188
CAS :<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3HSP90-IN-9
<p>HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.</p>Couleur et forme :SolidIsopyrazam
CAS :<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Formule :C20H23F2N3OCouleur et forme :SolidMasse moléculaire :359.41Antifungal agent 127
CAS :<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Formule :C13H12ClN3OCouleur et forme :SolidMasse moléculaire :261.707Antifungal agent 125
CAS :<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formule :C13H10BrNO4SCouleur et forme :SolidMasse moléculaire :356.192Hyalodendrin
CAS :<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formule :C14H16N2O3S2Couleur et forme :SolidMasse moléculaire :324.42WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46CDA-IN-3
CAS :<p>CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.</p>Formule :C16H27N3O3S2Couleur et forme :SolidMasse moléculaire :373.534CDA-IN-2
CAS :<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formule :C17H16N2O7Couleur et forme :SolidMasse moléculaire :360.318CDA-IN-1
CAS :<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formule :C23H23N3O5Couleur et forme :SolidMasse moléculaire :421.45Furametpyr
CAS :<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formule :C17H20ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.81Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55
