Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
874 produits trouvés pour "Antifongiques"
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Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Formule :C24H25N3O5Couleur et forme :SolidMasse moléculaire :435.47ATPase-IN-5
CAS :<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Formule :C10H10N4O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :266.28Nikkomycin Z
CAS :Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Formule :C20H25N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88bc1 Complex-IN-1
CAS :Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Formule :C16H22N6O5S2Couleur et forme :SolidMasse moléculaire :442.513SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55SDH-IN-25
CAS :<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Formule :C19H15BrCl2N2O4Couleur et forme :SolidMasse moléculaire :486.143Antifungal agent 134
CAS :Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Formule :C18H12F4N2O4Couleur et forme :SolidMasse moléculaire :396.29Pyriofenone
CAS :Pyriofenone (IKF-309) is an aryl phenyl ketone fungicide predominantly used to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. It exhibits moderate efficacy against rice blast disease. Pyriofenone functions through prevention, residue activity, treatment, rainfastness, translaminar action, and fumigation.Formule :C18H20ClNO5Couleur et forme :SolidMasse moléculaire :365.81Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.13CDA-IN-3
CAS :CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Formule :C16H27N3O3S2Couleur et forme :SolidMasse moléculaire :373.534RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formule :C41H78N8O5Couleur et forme :SolidMasse moléculaire :763.11HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Couleur et forme :SolidWQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Formule :C27H21N5O2SCouleur et forme :SolidMasse moléculaire :479.55Succinate dehydrogenase-IN-8
CAS :Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Formule :C22H19Cl2F2N5O2Couleur et forme :SolidMasse moléculaire :494.32Tenellin
CAS :Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41Yck2-IN-1
CAS :<p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>Formule :C19H11FN4Couleur et forme :SolidMasse moléculaire :314.316D75-4590
CAS :<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formule :C21H27N5Degré de pureté :98.56% - 98.85%Couleur et forme :SolidMasse moléculaire :349.474-Hydroxyvoriconazole
CAS :<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Degré de pureté :Min. 95%Rhizocticin A
CAS :Rhizocticin A is a potential inhibitor of threonine synthase.Formule :C11H22N5O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.32,7-Dihydroxynaphthalene
CAS :2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Formule :C10H8O2Couleur et forme :SolidMasse moléculaire :160.17Tetraconazole
CAS :Tetraconazole is an agent of pesticides.Formule :C13H11Cl2F4N3OCouleur et forme :Liquid ViscousMasse moléculaire :372.14Amphotericin A
CAS :<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Formule :C47H75NO17Degré de pureté :Min. 95%Masse moléculaire :926.09 g/mol
