Antifongiques
Les antifongiques sont des composés spécialement conçus pour arrêter, prévenir et éliminer la croissance des champignons. Dans cette catégorie, vous trouverez une large variété d'agents antifongiques essentiels pour la recherche et les applications thérapeutiques. Ces composés sont cruciaux pour traiter les infections fongiques et prévenir leur récurrence, ce qui en fait des outils vitaux tant dans les domaines médical qu'agricole. Les chercheurs et les professionnels de la santé peuvent explorer de nombreux antifongiques pour comprendre leurs mécanismes, optimiser leur efficacité et développer de nouveaux traitements pour combattre les souches de champignons résistantes. La vaste sélection d'antifongiques soutient les avancées continues dans la recherche sur les champignons et le développement de thérapies antifongiques efficaces.
871 produits trouvés pour "Antifongiques"
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CDA-IN-1
CAS :<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Formule :C15H14N2O6Couleur et forme :SolidMasse moléculaire :318.281Antifungal agent 100
CAS :<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formule :C23H21N3O4SCouleur et forme :SolidMasse moléculaire :435.5HDAC-IN-87
CAS :<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Formule :C13H7F5N4O2SCouleur et forme :SolidMasse moléculaire :378.277(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83Antifungal agent 127
CAS :<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Formule :C13H12ClN3OCouleur et forme :SolidMasse moléculaire :261.707Benzohydroxamic acid
CAS :<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.136Chitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47Antifungal agent 13
CAS :Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Formule :C14H20ClNO2S2Couleur et forme :SolidMasse moléculaire :333.9Antifungal agent 25
<p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>Couleur et forme :SolidAnCDA-IN-1
CAS :<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Formule :C16H13ClN4O2Couleur et forme :SolidMasse moléculaire :328.753HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Couleur et forme :SolidComplex III-IN-2
<p>Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.</p>Formule :C15H21ClN2O2SCouleur et forme :SolidMasse moléculaire :328.86Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formule :C23H22BrN3O5Couleur et forme :SolidMasse moléculaire :500.34Isopyrazam
CAS :Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Formule :C20H23F2N3OCouleur et forme :SolidMasse moléculaire :359.41Antibacterial agent 188
CAS :Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3Wikstrol A
CAS :Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Formule :C30H22O10Couleur et forme :SolidMasse moléculaire :542.49Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormule :C23H23N3O5Couleur et forme :SolidMasse moléculaire :421.45Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47Antifungal agent 12
Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51
