Antimicrobiens

9-Erythromycin 9-oxime is an activty inpurity, binding to the 50S ribosomal subunit of bacteria.

Flubendazole is a benzimidazole anthelmintic with action on microtubule formation in parasites and is used for treating intestinal worms in humans and animals.

Bedaquiline fumarate is the salt form of bedaquiline, a diarylquinoline molecule with an ATP synthetase inhibitory activity. Bedaquiline fumarate is an FDA-approved drug for the oral treatment of multidrug-resistant tuberculosis. Bedaquiline fumarate acts by inhibiting the activity of the ATP synthetase in the pathogenic bacterium Mycobacterium tuberculosis, even in the case of multiple antibiotic resistant strains.

Inhibitor of protein synthesis; streptogramin

Fluoroquinolone; gyrase inhibitor

Penicillin G potassium is a natural penicillin antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like meningitis, syphilis, and endocarditis.

Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI) with action on viral reverse transcriptase to block replication and is used for treating HIV/AIDS and chronic hepatitis B.

Tenofovir diphosphate is an antiviral compound, which is a key active metabolite derived from the prodrugs tenofovir disoproxil fumarate and tenofovir alafenamide, both originating from chemical synthesis. Its mode of action involves inhibiting the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5’-triphosphate, and causing chain termination after incorporation into viral DNA. This mechanism effectively prevents the replication of retroviral DNA, thus halting the progression of the infection.

Lincomycin is active against gram-positive bacteria such as staphylococci, streptococci, pneumococci, diphtheria bacillus, and clostridia. It is used to treat severe bacterial infections including: sepsis, osteomyelitis, septic endocarditis, pneumonia, pulmonary abscess, infected wounds, purulent meningitis and severe pseudomembranous colitis. Lincomycin is an alternative antibiotic for penicillin-resistant gram-positive bacteria.

Isepamicin sulfate - 70% is a semi-synthetic aminoglycoside antibiotic, which is derived from naturally occurring antibiotic compounds through chemical modifications. Its mode of action involves binding to the bacterial 30S ribosomal subunit, disrupting protein synthesis and consequently causing bacterial cell death. This mechanism of action is typical of aminoglycosides, characterized by their bactericidal properties against a broad spectrum of Gram-negative bacteria, with some efficacy against certain Gram-positive bacterial strains.

Abafungin is an antifungal agent and is used for treating fungal infections.

Sulfadoxine is a long-acting sulfonamide antibiotic with action on bacterial folate synthesis inhibition and is used for treating malaria in combination with pyrimethamine.

Sulopenem is a thiopenem antibiotic with action on bacterial cell wall synthesis and is used for treating uncomplicated urinary tract infections.

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Ionomycin calcium is a potent calcium ionophore, which is derived from natural sources such as certain Streptomyces species. Its primary mode of action involves facilitating the translocation of calcium ions (Ca^2+) across biological membranes, specifically transporting them from external environments or intracellular stores into the cytoplasm. This action significantly elevates intracellular calcium levels.

Tigecycline mesylate is a novel glycylcycline antibiotic, which is a derivative of the tetracycline class of antibiotics. It is a semi-synthetic product derived from minocycline, exhibiting a broad spectrum of antibacterial activity. Tigecycline mesylate functions through the inhibition of bacterial protein synthesis. It achieves this by binding to the 30S ribosomal subunit, thereby preventing the incorporation of amino acid residues into elongating peptide chains, a crucial step in protein production.

Cephalexin hydrochloride is a cephalosporin antibiotic, which is a type of beta-lactam antibiotic. It is derived from the fungus Acremonium, previously known as Cephalosporium, with a bactericidal mode of action. This compound works by inhibiting bacterial cell wall synthesis. Specifically, it binds to one or more of the penicillin-binding proteins (PBPs), which in turn disrupts the final stages of bacterial cell wall formation and results in cell lysis mediated through autolytic enzyme action.

E-Ceftazidime is a third-generation cephalosporin antibiotic, which is derived from the mold Acremonium. It functions by inhibiting bacterial cell wall synthesis, a crucial component for bacterial survival and replication. This inhibition occurs through the binding to specific penicillin-binding proteins (PBPs) within the bacterial cell wall, thus preventing cross-linking of the peptidoglycan chains, which results in the eventual lysis and death of the bacterial cell.