
Antiviraux
Les antiviraux sont des composés spécifiquement conçus pour inhiber la réplication et la propagation des virus, jouant un rôle crucial dans le traitement et la prévention des infections virales. Dans cette catégorie, vous trouverez une sélection complète d'agents antiviraux destinés uniquement à des fins de recherche en laboratoire. Ces produits sont essentiels pour étudier les mécanismes viraux, développer de nouvelles thérapies antivirales et comprendre les schémas de résistance. Les chercheurs peuvent utiliser ces antiviraux pour évaluer l'efficacité et la sécurité des traitements potentiels, contribuant ainsi à l'avancement de la science médicale et au développement de médicaments antiviraux innovants. La disponibilité de divers agents antiviraux soutient la recherche de pointe en virologie et améliore notre capacité à combattre les maladies virales.
765 produits trouvés pour "Antiviraux"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
T-705RMP TEA Salt >80% (contain inorganics)
CAS :<p>Applications T-705RMP TEA Salt is a metabolite of T-705RMP (CAS# 356783-08-9), which is a reagent used for the preparation of pyrazine-ribofuranose derivatives as antiviral agents that are useful in the treatment of viral infections. T-705 (Favipiravir) [F103350] gets converted to T-705RMP by host cells, but T-705RMP has little inhibitory effect on the replication of the host cells based on biological studies.<br>References Zhong, B., et al.: Faming Zhuanli Shenqing, 2014:924257 (2014); Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005)<br></p>Formule :C10H13FN3O9P•xC6H15NCouleur et forme :NeatMasse moléculaire :369.20 + x(101.19)1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-b-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide
CAS :Produit contrôlé<p>Applications 1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide is an intermediate in the synthesis of 2’-Deoxyribavirin-5’-triphosphate (D2149940) Triethylamine Salt, a potential new inhibitor for HIV-1 replication.<br>References Vivet-Boudou, V., et al.: Nucleos. Nucleot. Nucl., 26, 743 (2007);<br></p>Formule :C20H38N4O5Si2Couleur et forme :NeatMasse moléculaire :470.711-[2-O-(Phenoxythioxomethyl)-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide
CAS :Produit contrôlé<p>Applications 1-[2-O-(Phenoxythioxomethyl)-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide is an intermediate in the synthesis of 2’-Deoxyribavirin-5’-triphosphate (D2149940) Triethylamine Salt, a potential new inhibitor for HIV-1 replication.<br>References Vivet-Boudou, V., et al.: Nucleos. Nucleot. Nucl., 26, 743 (2007);<br></p>Formule :C27H42N4O7SSi2Couleur et forme :NeatMasse moléculaire :622.88Tenofovir diphosphate
CAS :<p>Tenofovir diphosphate is an antiviral compound, which is a key active metabolite derived from the prodrugs tenofovir disoproxil fumarate and tenofovir alafenamide, both originating from chemical synthesis. Its mode of action involves inhibiting the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5’-triphosphate, and causing chain termination after incorporation into viral DNA. This mechanism effectively prevents the replication of retroviral DNA, thus halting the progression of the infection.</p>Formule :C9H16N5O10P3Degré de pureté :Min. 95%Masse moléculaire :447.17 g/molAcetyl daclatasvir
CAS :<p>Acetyl daclatasvir is a direct-acting antiviral agent, which is chemically derived from a series of small-molecule inhibitors. The source of this compound lies in rational drug design, focusing on targeting specific viral proteins involved in the replication of hepatitis C virus (HCV). Its mode of action involves inhibiting the NS5A protein, a non-structural protein essential for HCV RNA replication and virion assembly. By binding to NS5A, acetyl daclatasvir disrupts the replication complex, effectively halting the virus's ability to multiply within the host cells.</p>Degré de pureté :Min. 95%HCV-IN-30
CAS :HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Formule :C36H44N6O4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :624.775,6,7,8-Tetrahydro-1-naphthalenol
CAS :Produit contrôlé<p>Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.<br>References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);<br></p>Formule :C10H12OCouleur et forme :NeatMasse moléculaire :148.2Nelfinavir Sulfone
CAS :Produit contrôlé<p>Impurity Nelfinavir Sulphone Impurity<br>Applications Nelfinavir Sulfone is an impurity of Nelfinavir Mesylate (N389750). It is a COVID19-related research product.<br>References Aymard, G., et al.: J. Chromatogr. B, 744, 227 (2000), Jing, Q., et al.: J. Pharm. Biomed. Anal., 41, 1065 (2006),<br></p>Formule :C32H45N3O6SCouleur et forme :NeatMasse moléculaire :599.78(S)-Methyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
CAS :Produit contrôléFormule :C17H21F2NO3Couleur et forme :NeatMasse moléculaire :325.35(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate
CAS :Produit contrôléFormule :C22H28O4SSiCouleur et forme :NeatMasse moléculaire :416.61(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.<br>References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);<br></p>Formule :C28H61FN5O14P3Couleur et forme :Off White SolidMasse moléculaire :803.73α-Bromoacetosyringone
CAS :Produit contrôléFormule :C10H11BrO4Couleur et forme :NeatMasse moléculaire :275.11-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
CAS :Produit contrôlé<p>Impurity Atazanavir Impurity B<br>Applications An intermediate for the preparation of antiviral protease inhibitors. Atazanavir Impurity B<br>References Fassler, A., et al.: J. Med. Chem., 39, 3203 (1996), Bold, G., et al.: J. Med. Chem., 41, 3387 (1998).<br></p>Formule :C17H21N3O2Couleur et forme :NeatMasse moléculaire :299.37Zanamivir Azide Methyl Ester
CAS :Produit contrôlé<p>Applications An intermediate used in the preparation of Zanamivir derivatives.<br>References Andrews, D., et al.: Eur. J. Med. Chem., 34, 563 (1999), Altamore, T., et al.: Bioorg. Med. Chem., 14, 1126 (2006),<br></p>Formule :C12H18N4O7Couleur et forme :NeatMasse moléculaire :330.29Baloxavir-d4
CAS :Produit contrôléFormule :C25D4H16F2N2O4SCouleur et forme :NeatMasse moléculaire :486.524Levovirin
CAS :Produit contrôlé<p>Applications Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.<br>References Ramasamy, K.S. et al.: J. Med. Chem., 43, 1019 (2000); Fang, C. et al.: J. Appl. Toxicol., 23, 453 (2003):<br></p>Formule :C8H12N4O5Couleur et forme :NeatMasse moléculaire :244.20R 77975
CAS :Produit contrôlé<p>Applications R 77975 is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.<br>References Morley, A. et al.: Bioorg. Med. Chem. Lett., 21, 6031 (2011); Tomkinson, N. et al.: Bioorg. Med. Chem. Lett., 22, 7494 (2012);<br></p>Formule :C21H27N3O3Couleur et forme :NeatMasse moléculaire :369.461,2,4-Triazole-3-carboxylic Acid
CAS :<p>Impurity Ribavirin EP Impurity C<br>Applications 1,2,4-Triazole-3-carboxylic Acid (Ribavirin EP Impurity C) is a major metabolite of the antiviral agent Ribavirin (R414475).<br>References Miller, J.P. et al.: Ann. N.Y. Acad. Sci., 284, 211 (1977); Catlin, D. et al.: Ribavirin: Broad Spec. Antivir. Ag., 83 (1980); Lin, C.C. et al.: Antimicrob. Ag. Chemother., 50, 2368 (2006);<br></p>Formule :C3H3N3O2Couleur et forme :White SolidMasse moléculaire :113.075S-2-Amino-5-dibenzylamino-4-oxo-1,6-diphenylhex-2-ene
CAS :Produit contrôlé<p>Applications An intermediate in the synthesis of Ritonavir.<br>References Sham, H., et al.: Bioorg. Med. Chem. Lett., 12, 3101 (2002),<br></p>Formule :C32H32N2OCouleur et forme :NeatMasse moléculaire :460.613,4-Difluoroaniline-2,6-d2
CAS :Produit contrôlé<p>Applications 3,4-Difluoroaniline-2,6-d2 (CAS# 1061566-62-8) can be used in its derivative form as an antiviral agent for Hepatitis B.<br>References Qiu, Y.L., et.al., U.S. Pat. Appl. Publ., 187,(2019);<br></p>Formule :C6H3D2F2NCouleur et forme :NeatMasse moléculaire :131.12


