Antiparasitaires
Les antiparasitaires sont des composés conçus pour traiter et prévenir les infections parasitaires en inhibant la croissance et la survie des parasites. Cette catégorie comprend une gamme d'agents antiparasitaires destinés exclusivement à un usage en laboratoire et non à la consommation humaine. Ces produits sont essentiels à des fins de recherche, permettant aux scientifiques d'étudier les cycles de vie des parasites, les mécanismes d'action et le développement de la résistance. L'utilisation d'antiparasitaires en laboratoire aide à la découverte et à l'optimisation de nouveaux traitements pour les maladies parasitaires, contribuant aux avancées en parasitologie médicale et vétérinaire. Les chercheurs comptent sur ces produits pour améliorer leur compréhension des infections parasitaires et développer des thérapies plus efficaces.
704 produits trouvés pour "Antiparasitaires"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
GNF179
CAS :<p>GNF179 is an optimized 8,8-dimethyl IP analog.</p>Formule :C22H23ClFN5ODegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :427.9LASSBio-1985
<p>LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.</p>Formule :C18H22N2O7Couleur et forme :SolidMasse moléculaire :378.38CpNMT-IN-1
<p>CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.</p>Formule :C25H25ClN4O4SCouleur et forme :SolidMasse moléculaire :513.008Alkaline tryptase-IN-1
<p>Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.</p>Formule :C29H33BrN2O2SCouleur et forme :SolidMasse moléculaire :553.55TSO-13
<p>TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.</p>Formule :C32H36N4O4S2Couleur et forme :SolidMasse moléculaire :604.78β-Hederin
CAS :<p>β-Hederin has antileishmanial activity. β-Hederin has apoptotic effect on cancer cells, it could be a promising candidate for chemotherapy of breast cancer.</p>Formule :C41H66O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :734.96Mepartricin
CAS :<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Couleur et forme :SolidAAP4
<p>AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.</p>Formule :C21H23BrClN7Couleur et forme :SolidMasse moléculaire :488.811Schizophyllan
CAS :<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Couleur et forme :SolidAntiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Couleur et forme :Odour SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formule :C18H27F3N8O8SCouleur et forme :SolidMasse moléculaire :572.52Antitrypanosomal agent 23
<p>Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.</p>Formule :C14H16N4O7Couleur et forme :SolidMasse moléculaire :352.1019Gypsogenic acid
CAS :<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formule :C30H46O5Couleur et forme :SolidMasse moléculaire :486.68Norselic acid B
CAS :<p>Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.</p>Formule :C29H44O4Couleur et forme :SolidMasse moléculaire :456.657Antiproliferative agent-56
<p>Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.</p>Couleur et forme :Odour SolidNitroxynil
CAS :<p>Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.</p>Formule :C7H3IN2O3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :290.01Azlocillin sodium salt
CAS :<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formule :C20H22N5NaO6SDegré de pureté :97.63% - 98.302%Couleur et forme :SolidMasse moléculaire :483.47ML251
CAS :<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formule :C17H13Cl2N3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :426.27Antimalarial agent 43
<p>Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.</p>Couleur et forme :Odour SolidFebrifugine dihydrochloride
CAS :<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formule :C16H21Cl2N3O3Degré de pureté :98.27% - 99.85%Couleur et forme :SolidMasse moléculaire :374.26
