Antiparasitaires
Les antiparasitaires sont des composés conçus pour traiter et prévenir les infections parasitaires en inhibant la croissance et la survie des parasites. Cette catégorie comprend une gamme d'agents antiparasitaires destinés exclusivement à un usage en laboratoire et non à la consommation humaine. Ces produits sont essentiels à des fins de recherche, permettant aux scientifiques d'étudier les cycles de vie des parasites, les mécanismes d'action et le développement de la résistance. L'utilisation d'antiparasitaires en laboratoire aide à la découverte et à l'optimisation de nouveaux traitements pour les maladies parasitaires, contribuant aux avancées en parasitologie médicale et vétérinaire. Les chercheurs comptent sur ces produits pour améliorer leur compréhension des infections parasitaires et développer des thérapies plus efficaces.
704 produits trouvés pour "Antiparasitaires"
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4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS :<p>4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.</p>Formule :C41H60O11Degré de pureté :Min. 95%Masse moléculaire :728.91 g/molPF 1022A
CAS :<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>Formule :C52H76N4O12Degré de pureté :Min. 95%Masse moléculaire :949.18 g/molHalofuginone
CAS :<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formule :C16H17BrClN3O3Degré de pureté :99.53%Couleur et forme :Off-White SolidMasse moléculaire :414.68Satranidazole
CAS :<p>Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.</p>Formule :C8H11N5O5SDegré de pureté :Min. 95%Masse moléculaire :289.27 g/molICA
CAS :<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Formule :C13H10N4SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :254.31Piperaquine
CAS :<p>Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.</p>Formule :C29H32Cl2N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.51BPH-715
CAS :<p>BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.</p>Formule :C17H31NO7P2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :423.38Quinfamide
CAS :<p>Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.</p>Formule :C16H13Cl2NO4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :354.18Halofuginone hydrobromide
CAS :<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formule :C16H17BrClN3O3·HBrDegré de pureté :97.01% - 99.73%Couleur et forme :SolidMasse moléculaire :495.59Antimalarial agent 26
CAS :<p>Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.</p>Formule :C20H22N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41Antiparasitic agent-18
CAS :<p>Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.</p>Formule :C25H21N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.48Antimalarial agent 19
CAS :<p>Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.</p>Formule :C22H33Cl2N5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.5Antimalarial agent 24
CAS :<p>Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM</p>Formule :C20H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.37Antimalarial agent 29
CAS :<p>Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.</p>Formule :C18H10ClF3N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.73Antileishmanial agent-14
CAS :<p>Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by</p>Formule :C23H26ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.91Insecticidal agent 2
CAS :<p>Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].</p>Formule :C16H8ClF7N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.69Antileishmanial agent-15
CAS :<p>Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.</p>Formule :C28H39N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.64Epsiprantel
CAS :<p>Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.</p>Formule :C20H26N2O2Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :326.43CRK12-IN-2
CAS :<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Formule :C23H33F2N5O3S2Degré de pureté :99.26% - 99.70%Couleur et forme :SolidMasse moléculaire :529.67Symetine
CAS :<p>Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.</p>Formule :C30H48N2O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :468.71
