Antiparasitaires
Les antiparasitaires sont des composés conçus pour traiter et prévenir les infections parasitaires en inhibant la croissance et la survie des parasites. Cette catégorie comprend une gamme d'agents antiparasitaires destinés exclusivement à un usage en laboratoire et non à la consommation humaine. Ces produits sont essentiels à des fins de recherche, permettant aux scientifiques d'étudier les cycles de vie des parasites, les mécanismes d'action et le développement de la résistance. L'utilisation d'antiparasitaires en laboratoire aide à la découverte et à l'optimisation de nouveaux traitements pour les maladies parasitaires, contribuant aux avancées en parasitologie médicale et vétérinaire. Les chercheurs comptent sur ces produits pour améliorer leur compréhension des infections parasitaires et développer des thérapies plus efficaces.
704 produits trouvés pour "Antiparasitaires"
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Diethyl Isobutylmalonate
CAS :Produit contrôlé<p>Applications Diethyl Isobutylmalonate is used as a reagent in the synthesis of quinoline-based zinc metallo-aminopeptidase inhibitors which have antimalarial activity.<br>References Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003)<br></p>Formule :C11H20O4Couleur et forme :NeatMasse moléculaire :216.275-Nitro-1H-quinolin-2-one
CAS :Produit contrôlé<p>Applications 5-Nitro-1H-quinolin-2-one is used in the synthetic preparation of novel antileishmanial agents for Leishmania donovani promastigotes.<br>References Paloque, L., et al.: Europ. J. Med. Chem., 54, 75 (2012);<br></p>Formule :C9H6N2O3Couleur et forme :NeatMasse moléculaire :190.163-Chloro-N-(3-methoxyphenyl)propanamide
CAS :Produit contrôlé<p>Applications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs.<br>References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);<br></p>Formule :C10H12ClNO2Couleur et forme :NeatMasse moléculaire :213.6623-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS
CAS :Produit contrôléFormule :C42H66O8SiCouleur et forme :NeatMasse moléculaire :727.054-(Aminomethyl)-cyclohexanone Hydrochloride
CAS :Produit contrôlé<p>Applications 4-(Aminomethyl)-cyclohexanone Hydrochloride is used to prepare dispiro-1,2,4-trioxolanes with antimalarial activities. It is also used to synthesize aminopyrimidines as SYK inhibitors useful in the treatment of SYK-mediated diseases.<br>References Tang, Y., et al.: Bioorg. Med. Chem. Lett., 17, 1260 (2007); Altman, M., et al.: PCT Int. Appl. (2011), WO 2011075515 A1 20110623<br></p>Formule :C7H13NO·HClCouleur et forme :NeatMasse moléculaire :127.18 + 36.463-Aminopropionitrile (Stabilized with K2CO3)
CAS :Produit contrôléFormule :C3H6N2Couleur et forme :NeatMasse moléculaire :70.09Pseurotin A
CAS :Produit contrôlé<p>Applications Pseurotin A shows antiparasitic and anticancer activity. It exhibits inhibition towards IgE (immunoglobin E) production.<br>References Martinez-Luis, S. et al.: Nat. Prod. Comm., 7, 165 (2012); Bioorg. Med. Chem. Lett., 19, 1457 (2009);<br></p>Formule :C22H25NO8Couleur et forme :NeatMasse moléculaire :431.444-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one
CAS :Produit contrôlé<p>Applications 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one is a Kawain (K145490) derivative that is known to exhibit antimalarial and antituberculosis activities. 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one has been identified as a lead compound for the dual treatment of malaria and leishmaniasis.<br>References McCracken, S.T., et al.: Bioorg. Med. Chem., 20, 1482 (2012); Elzaawely, A.A.. et al.: Food. Chem., 103, 486 (2007); Xuan, T.D., et al.: J. Natural. Med., 62, 188 (2008);<br></p>Formule :C14H14O3Couleur et forme :NeatMasse moléculaire :230.262'-O-(2-Methoxyethyl)-5-methylcytidine (~90%)
CAS :Produit contrôléFormule :C13H21N3O6Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :315.324,4'-Dimethyldiphenylamine
CAS :Produit contrôlé<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>Formule :C14H15NCouleur et forme :NeatMasse moléculaire :197.282-Hydroxy-1-methyl-9,10-anthracenedione
CAS :Produit contrôléFormule :C15H10O3Couleur et forme :NeatMasse moléculaire :238.242,5-Diacetoxy-2,5-dihydrofuran (Mixture of Isomers) (>90%)
CAS :Produit contrôlé<p>Applications 2,5-Diacetoxy-2,5-dihydrofuran is used as a reagent to synthesize Mexicanin H, a biologically active sesquiterpene lactone that exhibits antiparasitic activity against Trypanosoma cruzi (a parasite that causes Chagas disease)<br>References Jimenez-Ortiz, V., et al.: Parasitology, 91, 170 (2005); Romo, J., et al.: Tetrahedron Lett., No vol. given, 1029 (1966)<br></p>Formule :C8H10O5Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :186.16PBD-5,11-dione
CAS :Produit contrôlé<p>Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.<br></p>Formule :C12H12N2O2Couleur et forme :NeatMasse moléculaire :216.243-[(Dimethylamino)methyl]-2-hexanone
CAS :Produit contrôléFormule :C9H19NOCouleur et forme :ColourlessMasse moléculaire :157.25Benzenebutanoic Acid Ethyl Ester
CAS :Produit contrôlé<p>Applications Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.<br>References Hamze, A. et al.: J. Med. Chem., 48, 3639 (2005); Ward, R. et al.: J. Med. Chem., 55, 3285 (2012);<br></p>Formule :C12H16O2Couleur et forme :NeatMasse moléculaire :192.25Tizoxanide - 98%
CAS :<p>Anti-parasitic; pyruvate ferredoxin oxidoreductase inhibitor</p>Formule :C10H7N3O4SDegré de pureté :Min. 95%Masse moléculaire :265.01573Oxfendazole
CAS :<p>Oxfendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating gastrointestinal parasites in livestock.</p>Formule :C15H13N3O3SDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :315.35 g/molAmoscanate
CAS :<p>Amoscanate is an antischistosomal agent, which is a synthetic compound with a broad spectrum of activity against parasitic infections. Its mode of action involves the disruption of parasite metabolism and structure, ultimately leading to the elimination of schistosomes. Schistosomes are trematode worms responsible for schistosomiasis, a significant parasitic disease affecting millions of people worldwide.</p>Formule :C13H9N3O2SDegré de pureté :Min. 95%Masse moléculaire :271.3 g/molIvermectin
CAS :<p>Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.</p>Formule :C48H74O14Degré de pureté :85%MinMasse moléculaire :875.1 g/mol4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS :<p>4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.</p>Formule :C41H60O11Degré de pureté :Min. 95%Masse moléculaire :728.91 g/molPF 1022A
CAS :<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>Formule :C52H76N4O12Degré de pureté :Min. 95%Masse moléculaire :949.18 g/molHalofuginone
CAS :<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formule :C16H17BrClN3O3Degré de pureté :99.53%Couleur et forme :Off-White SolidMasse moléculaire :414.68Satranidazole
CAS :<p>Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.</p>Formule :C8H11N5O5SDegré de pureté :Min. 95%Masse moléculaire :289.27 g/molICA
CAS :<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Formule :C13H10N4SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :254.31Piperaquine
CAS :<p>Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.</p>Formule :C29H32Cl2N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.51BPH-715
CAS :<p>BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.</p>Formule :C17H31NO7P2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :423.38Quinfamide
CAS :<p>Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.</p>Formule :C16H13Cl2NO4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :354.18Halofuginone hydrobromide
CAS :<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formule :C16H17BrClN3O3·HBrDegré de pureté :97.01% - 99.73%Couleur et forme :SolidMasse moléculaire :495.59Antimalarial agent 26
CAS :<p>Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.</p>Formule :C20H22N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41Antiparasitic agent-18
CAS :<p>Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.</p>Formule :C25H21N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.48Antimalarial agent 19
CAS :<p>Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.</p>Formule :C22H33Cl2N5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.5Antimalarial agent 24
CAS :<p>Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM</p>Formule :C20H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.37Antimalarial agent 29
CAS :<p>Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.</p>Formule :C18H10ClF3N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.73Antileishmanial agent-14
CAS :<p>Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by</p>Formule :C23H26ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.91Insecticidal agent 2
CAS :<p>Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].</p>Formule :C16H8ClF7N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.69Antileishmanial agent-15
CAS :<p>Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.</p>Formule :C28H39N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.64Epsiprantel
CAS :<p>Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.</p>Formule :C20H26N2O2Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :326.43CRK12-IN-2
CAS :<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Formule :C23H33F2N5O3S2Degré de pureté :99.26% - 99.70%Couleur et forme :SolidMasse moléculaire :529.67Symetine
CAS :<p>Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.</p>Formule :C30H48N2O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :468.71(Rac)-ACT-451840
CAS :<p>(Rac)-ACT-451840 is an isomer of ACT-451840 exhibiting antimalarial activity against Plasmodium falciparum NF54.</p>Formule :C47H54N6O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :750.97Chalcone 4 hydrate
CAS :<p>Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.</p>Formule :C16H15ClO4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :306.74Phosphodiesterase-IN-1
CAS :<p>Phosphodiesterase-IN-1 (Compound 7), a phosphodiesterase (PDE) inhibitor, exhibits anti-Plasmodium and antiproliferative activities. It effectively inhibits P. falciparum (strain 3D7) with an IC 50 value of 0.64 μM [1].</p>Formule :C15H15FN4OCouleur et forme :SolidMasse moléculaire :286.3MMV006833
CAS :<p>MMV006833 is an inhibitor of Plasmodium falciparum. It targets the lipid transfer protein PfSTART1, inhibiting the ring-stage development of Plasmodium falciparum.</p>Formule :C19H27ClN2O4SCouleur et forme :SolidMasse moléculaire :414.95Topoisomerase II inhibitor 16
CAS :<p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>Formule :C19H12F4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.33SQ109
CAS :<p>SQ109 (NSC-722041) is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.</p>Formule :C22H38N2Degré de pureté :99.70% - 99.91%Couleur et forme :SolidMasse moléculaire :330.55Antitrypanosomal agent 2
CAS :<p>Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.</p>Formule :C17H13N5O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :335.32Artelinic acid
CAS :<p>Artelinic acid is an artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.</p>Formule :C23H30O7Degré de pureté :97.49% - 97.69%Couleur et forme :SolidMasse moléculaire :418.48Bithionol sulfoxide
CAS :<p>Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects against parasites, inhibiting Fasciola hepatica and Schistosoma mansoni.</p>Formule :C12H6Cl4O3SDegré de pureté :98.76%Couleur et forme :Off White To Tinch Pink Crystalline PowderMasse moléculaire :372.05Rufigallol
CAS :<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Formule :C14H8O8Degré de pureté :98.92% - 99.27%Couleur et forme :SolidMasse moléculaire :304.21
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